دورية أكاديمية
Establishing a balloon pulmonary angioplasty program for chronic thromboembolic pulmonary hypertension: A United States single-center experience.
| العنوان: | Establishing a balloon pulmonary angioplasty program for chronic thromboembolic pulmonary hypertension: A United States single-center experience. |
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| المؤلفون: | Carlozzi LN; Seattle Children's Hospital, Division of Cardiology, USA., Lee J; Critical Care, Pulmonary and Sleep Associates, Denver, CO, USA., Barros LM; University of Washington, Division of Pulmonary, Critical Care, and Sleep Medicine, USA., Buber Y; University of Washington, Division of Cardiology, USA., Chen DL; University of Washington, Division of Nuclear Medicine, USA., Mulligan M; University of Washington, Division of Cardiothoracic Surgery, USA., Ordovas K; University of Washington, Department of Radiology, USA., Ralph DD; University of Washington, Division of Pulmonary, Critical Care, and Sleep Medicine, USA., Rayner SG; University of Washington, Division of Pulmonary, Critical Care, and Sleep Medicine, USA., Leary PJ; University of Washington, Division of Pulmonary, Critical Care, and Sleep Medicine, USA; University of Washington, Department of Epidemiology, USA., Steinberg ZL; University of Washington, Division of Cardiology, USA. Electronic address: ZSteinberg@cardiology.washington.edu. |
| المصدر: | Respiratory medicine [Respir Med] 2023 May; Vol. 211, pp. 107215. Date of Electronic Publication: 2023 Mar 17. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 8908438 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-3064 (Electronic) Linking ISSN: 09546111 NLM ISO Abbreviation: Respir Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2003- : Oxford : Elsevier Original Publication: London : Baillière Tindall, in association with the British Thoracic Society, [c1989- |
| مواضيع طبية MeSH: | Hypertension, Pulmonary*/etiology , Hypertension, Pulmonary*/surgery , Pulmonary Embolism*/complications , Pulmonary Embolism*/surgery , Angioplasty, Balloon*/adverse effects , Angioplasty, Balloon*/methods, Humans ; Retrospective Studies ; Chronic Disease ; Pulmonary Artery/surgery ; Treatment Outcome |
| مستخلص: | Introduction: Balloon pulmonary angioplasty (BPA) is a less invasive treatment alternative for patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are unable to move forward with pulmonary thromboendarterectomy. This report describes a single-center experience with a nascent BPA program in the United States (US). Methods: All patients who underwent BPA between August 2018-2021 were included in this retrospective, single-center observational cohort. Pre- and post-procedure clinical information was collected, along with procedural characteristics. Results: Thirty patients began their BPA series during the study period. The majority of patients had segmental disease (n = 25, 83.3%). A total of 135 BPA procedures were performed on 417 segments. On average, patients completed 4.5 sessions and the majority of patients (n = 23, 76.7%) underwent more than 2. There were 24 episodes of hemoptysis and 20 procedural events that required treatment, typically with either heparin reversal or balloon tamponade. Of 26 participants with completed series, mean PA pressure (-6 mmHg, 95% CI -9 to -4 mmHg, p = 0.0001), PVR (-1.9 Wood units, 95% CI -2.9 to -1.0, p = 0.0002), and pulmonary compliance (-1.0 mL/mmHg, 95% CI -1.5 to -0.5, p = 0.0002) improved. Improvement was also seen in NYHA functional classification and walk distance (p = 0.01). Two deaths occurred, with one death peri-procedurally. Conclusion: This paper describes an early experience with BPA at a single US center. Improvement in non-invasive and invasive metrics were seen without adding a significant morbidity to an already high-risk patient population. (Copyright © 2023 Elsevier Ltd. All rights reserved.) |
| تواريخ الأحداث: | Date Created: 20230319 Date Completed: 20230425 Latest Revision: 20230425 |
| رمز التحديث: | 20230425 |
| DOI: | 10.1016/j.rmed.2023.107215 |
| PMID: | 36934856 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1532-3064 |
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| DOI: | 10.1016/j.rmed.2023.107215 |