دورية أكاديمية
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When cleaning facilitates cluttering - genome editing in ciliates.

التفاصيل البيبلوغرافية
العنوان: When cleaning facilitates cluttering - genome editing in ciliates.
المؤلفون: Seah BKB; Max Planck Institute for Biology, 72076 Tübingen, Germany., Swart EC; Max Planck Institute for Biology, 72076 Tübingen, Germany. Electronic address: estienne.swart@tuebingen.mpg.de.
المصدر: Trends in genetics : TIG [Trends Genet] 2023 May; Vol. 39 (5), pp. 344-346. Date of Electronic Publication: 2023 Mar 21.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Trends Journals Country of Publication: England NLM ID: 8507085 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0168-9525 (Print) Linking ISSN: 01689525 NLM ISO Abbreviation: Trends Genet Subsets: MEDLINE
أسماء مطبوعة: Publication: Cambridge : Elsevier Trends Journals
Original Publication: [Amsterdam, The Netherlands : Elsevier Science Publishers B.V., c1985-
مواضيع طبية MeSH: Gene Editing* , Ciliophora*/genetics, Genome/genetics ; DNA Transposable Elements
مستخلص: Many organisms remove DNA from their genomes during development. This has foremost been characterized as a means of defending genomes against mobile elements. However, genome editing actually hides such elements from purifying selection, with the survivors evolving approximately neutrally, 'cluttering' the germline genome, enabling it to enlarge over time.
Competing Interests: Declaration of interests No interests are declared.
(Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
فهرسة مساهمة: Keywords: epigenetics; genome defense; genome editing; genome reorganization; germline–soma differentiation; transposable elements
المشرفين على المادة: 0 (DNA Transposable Elements)
تواريخ الأحداث: Date Created: 20230322 Date Completed: 20230420 Latest Revision: 20230521
رمز التحديث: 20230522
DOI: 10.1016/j.tig.2023.02.016
PMID: 36949004
قاعدة البيانات: MEDLINE
الوصف
تدمد:0168-9525
DOI:10.1016/j.tig.2023.02.016