دورية أكاديمية

Pruritus in cutaneous graft-versus-host disease: A systematic review.

التفاصيل البيبلوغرافية
العنوان: Pruritus in cutaneous graft-versus-host disease: A systematic review.
المؤلفون: Zhu J; Department of Dermatology, University Hospital Basel, Basel, Switzerland., Navarini AA; Department of Dermatology, University Hospital Basel, Basel, Switzerland., Halter JP; Department of Haematology, University Hospital Basel, Basel, Switzerland., Mueller SM; Department of Dermatology, University Hospital Basel, Basel, Switzerland.
المصدر: Journal of the European Academy of Dermatology and Venereology : JEADV [J Eur Acad Dermatol Venereol] 2023 Jul; Vol. 37 (7), pp. 1276-1283. Date of Electronic Publication: 2023 Apr 05.
نوع المنشور: Systematic Review; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9216037 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3083 (Electronic) Linking ISSN: 09269959 NLM ISO Abbreviation: J Eur Acad Dermatol Venereol Subsets: MEDLINE
أسماء مطبوعة: Publication: Oxford : Wiley-Blackwell
Original Publication: Amsterdam ; New York : Elsevier Science Publishers, c1992-
مواضيع طبية MeSH: Skin Diseases*/drug therapy , Graft vs Host Disease* , Hematopoietic Stem Cell Transplantation*, Humans ; Antipruritics/therapeutic use ; Quality of Life ; Pruritus/drug therapy
مستخلص: Pruritus is a common symptom of cutaneous graft-versus-host disease (GVHD) following haematopoietic stem cell transplantation (HSCT). However, little is known about its prevalence, pathophysiology, perceptual characteristics, impact on quality of life and response to antipruritic therapies. The aim of this review was to determine the current knowledge on pruritus in cutaneous GVHD. The review was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analyses statement. Of the 338 studies screened, 13 were included. The prevalence of pruritus in cutaneous GVHD was reported in three studies, ranging from 37.0% to 63.8%. Only four trials used pruritus assessment tools. There was little or no information on the intensity of pruritus, its qualitative perception, the location of pruritus and the impact of pruritus on quality of life. Antipruritic treatments for GVHD-associated pruritus were mentioned in five studies (38.5%), including topical ointments (steroids, tacrolimus and calcipotriene), broadband UVB, systemic antihistamines and oral ursodeoxycholic acid. In conclusion, pruritus in cutaneous GVHD appears to be common, but very little is known about the pathophysiology, impact on quality of life and effective treatment options. Basic research and controlled clinical trials are warranted to improve knowledge and management of this important issue.
(© 2023 European Academy of Dermatology and Venereology.)
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معلومات مُعتمدة: Gottfried und Julia Bangerter-Rhyner-Stiftung
المشرفين على المادة: 0 (Antipruritics)
تواريخ الأحداث: Date Created: 20230323 Date Completed: 20230614 Latest Revision: 20230614
رمز التحديث: 20240628
DOI: 10.1111/jdv.19057
PMID: 36950958
قاعدة البيانات: MEDLINE
الوصف
تدمد:1468-3083
DOI:10.1111/jdv.19057