دورية أكاديمية
Adaptive living skills, sleep problems, and mental health disorders in adults with 22q11.21 deletion syndrome.
| العنوان: | Adaptive living skills, sleep problems, and mental health disorders in adults with 22q11.21 deletion syndrome. |
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| المؤلفون: | Leader G; Irish Centre for Autism and Neurodevelopmental Research, School of Psychology, National, University of Ireland, Galway, Ireland. Electronic address: geraldine.leader@nuigalway.ie., Curtin A; Irish Centre for Autism and Neurodevelopmental Research, School of Psychology, National, University of Ireland, Galway, Ireland., Shprintzen RJ; The Virtual Center for Velo-Cardio-Facial Syndrome, Inc, United States., Whelan S; Irish Centre for Autism and Neurodevelopmental Research, School of Psychology, National, University of Ireland, Galway, Ireland., Coyne R; Irish Centre for Autism and Neurodevelopmental Research, School of Psychology, National, University of Ireland, Galway, Ireland., Mannion A; Irish Centre for Autism and Neurodevelopmental Research, School of Psychology, National, University of Ireland, Galway, Ireland. |
| المصدر: | Research in developmental disabilities [Res Dev Disabil] 2023 May; Vol. 136, pp. 104491. Date of Electronic Publication: 2023 Mar 23. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Pergamon Press Country of Publication: United States NLM ID: 8709782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3379 (Electronic) Linking ISSN: 08914222 NLM ISO Abbreviation: Res Dev Disabil Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York : Pergamon Press, c1987- |
| مواضيع طبية MeSH: | DiGeorge Syndrome*/complications , DiGeorge Syndrome*/epidemiology , DiGeorge Syndrome*/genetics , Mental Disorders*/epidemiology , Mental Disorders*/genetics , Sleep Wake Disorders*/epidemiology , Sleep Wake Disorders*/genetics , 22q11 Deletion Syndrome*, Humans ; Adult ; Mental Health ; Activities of Daily Living |
| مستخلص: | Background: 22q11.21 deletion syndrome (22q11DS) is a neurodevelopmental syndrome caused by a microdeletion of genes at the 22q11.21 locus. It has a prevalence of 1:2000. This study investigated the prevalence of adaptive living skills, sleep problems, and mental health disorders in adults with 22q11DS and examined the relationship between these factors. Methods: Parents with an adult son or daughter with 22q11DS completed the following: A bespoke Demographic Information Questionnaire, Sleep Questionnaire (SQ-SP), Psychopathology in Autism Checklist (PAC), and Activities of Daily Living (ADL) scale. Descriptive statistics, correlations, and one-way between groups analysis of variance (ANOVA) were conducted. Results: Mental health difficulties, sleep problems, and low levels of adaptive living skills are prevalent in adults with 22q11DS. Strong positive correlations were identified between sleep problems, depression, and anxiety subscale scores and moderate negative correlations between depression, psychosis, and activities of daily living skills. Conclusion: Adults with 22q11DS need screening and treatment for mental health and sleep problems. Competing Interests: Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Conotruncal anomaly face syndrome; DiGeorge syndrome; Sedlačková syndrome; Velo-cardio-facial syndrome |
| تواريخ الأحداث: | Date Created: 20230325 Date Completed: 20230411 Latest Revision: 20230411 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.ridd.2023.104491 |
| PMID: | 36965410 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-3379 |
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| DOI: | 10.1016/j.ridd.2023.104491 |