تقرير
McKittrick-Wheelock Syndrome: A Case Report.
| العنوان: | McKittrick-Wheelock Syndrome: A Case Report. |
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| المؤلفون: | Marcinkevičiūtė K; Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania., Kryžauskas M; Clinic of Gastroenterology, Nephrourology, and Surgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania., Poškus T; Clinic of Gastroenterology, Nephrourology, and Surgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania. |
| المصدر: | Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2023 Mar 22; Vol. 59 (3). Date of Electronic Publication: 2023 Mar 22. |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2018- : Basel, Switzerland : MDPI Original Publication: Kaunas : Lietuvos gydytojų sąjunga |
| مواضيع طبية MeSH: | Adenoma, Villous*/complications , Adenoma, Villous*/diagnosis , Adenoma, Villous*/surgery , Rectal Neoplasms*/surgery , Water-Electrolyte Imbalance*/complications , Acute Kidney Injury*/etiology , Adenoma*/complications, Humans ; Middle Aged ; Syndrome ; Diarrhea/etiology ; Electrolytes |
| مستخلص: | An adenoma is the most typical large bowel tumor found in 30% of all screening colonoscopies. However, it is often asymptomatic but sometimes might lead to abdominal pain or bleeding of the rectum. Critical electrolyte disbalance and acute kidney injury caused by secretory diarrhea is an untypical clinical manifestation of adenoma. It has rarely been reported in the literature and is defined as McKittrick-Wheelock syndrome. A 61-year-old patient was hospitalized for heavy dyselectrolytemia, diarrhea, acute kidney injury, sepsis, and fever. After the renal function was corrected and electrolyte imbalance persisted, visual instrumental diagnostics tests revealed a large tumor in the sigmoid colon. Subsequently, the patient underwent surgical resection, which exhibited evidence of tubulovillous adenoma on pathology. The atypical signs of McKittrick-Wheelock syndrome and comorbidities can make the diagnostics challenging. When severe hyponatremia and hypokalemia are followed by persistent mucous diarrhea, the clinicians should suspect MWS as a possible reason for it. |
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| فهرسة مساهمة: | Keywords: McKittrick–Wheelock syndrome; electrolyte imbalance; tubulovillous adenoma; villous adenoma |
| المشرفين على المادة: | 0 (Electrolytes) |
| تواريخ الأحداث: | Date Created: 20230329 Date Completed: 20230330 Latest Revision: 20230331 |
| رمز التحديث: | 20230331 |
| مُعرف محوري في PubMed: | PMC10056017 |
| DOI: | 10.3390/medicina59030633 |
| PMID: | 36984634 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1648-9144 |
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| DOI: | 10.3390/medicina59030633 |