تقرير
McKittrick-Wheelock Syndrome: A Case Report.
العنوان: | McKittrick-Wheelock Syndrome: A Case Report. |
---|---|
المؤلفون: | Marcinkevičiūtė K; Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania., Kryžauskas M; Clinic of Gastroenterology, Nephrourology, and Surgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania., Poškus T; Clinic of Gastroenterology, Nephrourology, and Surgery, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, LT-03101 Vilnius, Lithuania. |
المصدر: | Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2023 Mar 22; Vol. 59 (3). Date of Electronic Publication: 2023 Mar 22. |
نوع المنشور: | Case Reports |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2018- : Basel, Switzerland : MDPI Original Publication: Kaunas : Lietuvos gydytojų sąjunga |
مواضيع طبية MeSH: | Adenoma, Villous*/complications , Adenoma, Villous*/diagnosis , Adenoma, Villous*/surgery , Rectal Neoplasms*/surgery , Water-Electrolyte Imbalance*/complications , Acute Kidney Injury*/etiology , Adenoma*/complications, Humans ; Middle Aged ; Syndrome ; Diarrhea/etiology ; Electrolytes |
مستخلص: | An adenoma is the most typical large bowel tumor found in 30% of all screening colonoscopies. However, it is often asymptomatic but sometimes might lead to abdominal pain or bleeding of the rectum. Critical electrolyte disbalance and acute kidney injury caused by secretory diarrhea is an untypical clinical manifestation of adenoma. It has rarely been reported in the literature and is defined as McKittrick-Wheelock syndrome. A 61-year-old patient was hospitalized for heavy dyselectrolytemia, diarrhea, acute kidney injury, sepsis, and fever. After the renal function was corrected and electrolyte imbalance persisted, visual instrumental diagnostics tests revealed a large tumor in the sigmoid colon. Subsequently, the patient underwent surgical resection, which exhibited evidence of tubulovillous adenoma on pathology. The atypical signs of McKittrick-Wheelock syndrome and comorbidities can make the diagnostics challenging. When severe hyponatremia and hypokalemia are followed by persistent mucous diarrhea, the clinicians should suspect MWS as a possible reason for it. |
References: | Int J Colorectal Dis. 2010 Jul;25(7):909-10. (PMID: 20165855) Intractable Rare Dis Res. 2016 Aug;5(3):218-21. (PMID: 27672546) Dis Colon Rectum. 1979 Sep;22(6):406-7. (PMID: 498898) Rom J Gastroenterol. 2005 Mar;14(1):63-6. (PMID: 15800695) Clin Exp Gastroenterol. 2013 Jun 20;6:85-9. (PMID: 23825927) Medicina (Kaunas). 2022 Apr 02;58(4):. (PMID: 35454349) Dis Colon Rectum. 1997 Dec;40(12):1494-5; discussion 1495-6. (PMID: 9407991) Case Rep Gastrointest Med. 2019 Jan 31;2019:3104187. (PMID: 30838142) Med J Aust. 2010 Feb 15;192(4):225-7. (PMID: 20170462) Ann Coloproctol. 2022 Jun;38(3):266-270. (PMID: 34256428) Case Rep Oncol Med. 2015;2015:242760. (PMID: 26682079) Med Klin (Munich). 2002 Oct 15;97(10):619-23. (PMID: 12386796) Ren Fail. 2014 Jun;36(5):811-3. (PMID: 24564376) BMJ Case Rep. 2013 Apr 15;2013:. (PMID: 23592821) J Korean Surg Soc. 2012 May;82(5):325-9. (PMID: 22563542) Clujul Med. 2016;89(2):301-3. (PMID: 27152085) Endocrinol Diabetes Metab Case Rep. 2016;2016:160013. (PMID: 27252863) CMAJ. 2015 Jun 16;187(9):676-678. (PMID: 25754711) Surg Endosc. 2014 Jul;28(7):2247. (PMID: 24671351) Cureus. 2021 Feb 12;13(2):e13308. (PMID: 33732563) Ann R Coll Surg Engl. 2018 Oct 16;:1-7. (PMID: 30322287) Surg Laparosc Endosc Percutan Tech. 2008 Oct;18(5):536-8. (PMID: 18936686) |
فهرسة مساهمة: | Keywords: McKittrick–Wheelock syndrome; electrolyte imbalance; tubulovillous adenoma; villous adenoma |
المشرفين على المادة: | 0 (Electrolytes) |
تواريخ الأحداث: | Date Created: 20230329 Date Completed: 20230330 Latest Revision: 20230331 |
رمز التحديث: | 20230331 |
مُعرف محوري في PubMed: | PMC10056017 |
DOI: | 10.3390/medicina59030633 |
PMID: | 36984634 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1648-9144 |
---|---|
DOI: | 10.3390/medicina59030633 |