دورية أكاديمية

Chemical Composition and Biological Activities of Essential Oils of Four Asarum Species Growing in Vietnam.

التفاصيل البيبلوغرافية
العنوان: Chemical Composition and Biological Activities of Essential Oils of Four Asarum Species Growing in Vietnam.
المؤلفون: Minh PTH; Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi 10072, Vietnam.; Faculty of Chemistry, Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi 10072, Vietnam., Tuan NT; Faculty of Chemistry, Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi 10072, Vietnam.; Institute of Life Sciences, Thai Nguyen University of Agriculture and Forestry, Quyet Thang, Thai Nguyen 24119, Vietnam., Van NTH; Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi 10072, Vietnam., Bich HT; Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi 10072, Vietnam., Lam DT; Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi 10072, Vietnam.; Faculty of Chemistry, Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi 10072, Vietnam.
المصدر: Molecules (Basel, Switzerland) [Molecules] 2023 Mar 12; Vol. 28 (6). Date of Electronic Publication: 2023 Mar 12.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, c1995-
مواضيع طبية MeSH: Oils, Volatile*/pharmacology , Oils, Volatile*/chemistry , Asarum*, Vietnam ; Microbial Sensitivity Tests ; Antioxidants/pharmacology
مستخلص: The essential oils (EOs) of the aerial parts of four Asarum species ( A. geophilum , A. yentunensis , A. splendens and A. cordifolium) were isolated by steam distillation and analyzed by the GC/MS method. The A. cordifolium EO contains 33 constituents with the main component being elemicine (77.20%). The A. geophilum EO was contains 49 constituents with the main components being determined as 9- epi -( E )-caryophyllene (18.43%), eudesm-7(11)-en-4-ol (13.41%), β -caryophyllene (8.05%) and phytol (7.23%). The A. yentunensis EO contains 26 constituents with the main components being safrole (64.74%) and sesquicineole (15.34%). The EO of A. splendens contains 41 constituents with the main components being 9- epi -(E)-caryophyllene (15.76%), eudesm-7(11)-en-4-ol (14.21%), β -caryophyllene (9.52%) and trans -bicyclogermacrene (7.50%). For antimicrobial activity, the A. yentunensis EO exhibited the highest inhibition activity against Staphylococcus aureus and the A. cordifolium EO against Bacillus subtillis (MIC values of 100 μg/mL). For antioxidant activity, the A. geophilum EO showed the highest potential with an SC (%) value of 63.34 ± 1.0%, corresponding to an SC 50 value of 28.57 µg/mL. For anti-inflammatory activity, the A. splendens EO exhibited the highest potential with an IC 50 value of 21.68 µg/mL, corresponding to an inhibition rate of NO production of 69.58 ± 1.3% and the percentage of cell life was 81.85 ± 0.9%.
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معلومات مُعتمدة: 104.01-2019.317 Vietnam National Foundation for Science and Technology Development
فهرسة مساهمة: Keywords: Asarum; Asarum cordifolium; Asarum geophilum; Asarum splendens; Asarum yentunensis; antimicrobial; antioxidant; essential oil
المشرفين على المادة: 0 (Oils, Volatile)
BHW853AU9H (caryophyllene)
0 (Antioxidants)
تواريخ الأحداث: Date Created: 20230329 Date Completed: 20230330 Latest Revision: 20230331
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10053891
DOI: 10.3390/molecules28062580
PMID: 36985550
قاعدة البيانات: MEDLINE
الوصف
تدمد:1420-3049
DOI:10.3390/molecules28062580