دورية أكاديمية
A Comparison of ICU Mortality Scoring Systems Applied to COVID-19.
| العنوان: | A Comparison of ICU Mortality Scoring Systems Applied to COVID-19. |
|---|---|
| المؤلفون: | Monk M; Internal Medicine, HCA Houston Kingwood/University of Houston College of Medicine, Kingwood, USA., Torres J; Internal Medicine, Univeristy of Houston/HCA Healthcare Kingwood, Houston, USA., Vickery K; Medical Education and Simulation, HCA Healthcare, Brentwood, USA., Jayaraman G; Pulmonary and Critical Care Medicine, HCA Houston Kingwood, Kingwood, USA., Sarva ST; Pulmonary and Critical Care Medicine, HCA Houston Kingwood, Kingwood, USA., Kesavan R; Pulmonary and Critical Care Medicine, HCA Houston Kingwood/University of Houston College of Medicine, Houston, USA. |
| المصدر: | Cureus [Cureus] 2023 Feb 24; Vol. 15 (2), pp. e35423. Date of Electronic Publication: 2023 Feb 24 (Print Publication: 2023). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Palo Alto, CA : Cureus, Inc. |
| مستخلص: | Background Over the past three years, COVID-19 has been a major source of mortality in intensive care units around the world. Many scoring systems have been developed to estimate mortality in critically ill patients. Our intent with this study was to compare the efficacy of these systems when applied to COVID-19. Methods The was a multicenter, retrospective cohort study of critically ill patients with COVID-19 admitted to 16 hospitals in Texas from February 2020 to March 2022. The Simplified Acute Physiology Score (SAPS) II, Acute Physiology and Chronic Health Evaluation (APACHE) II, Sequential Organ Failure Assessment (SOFA) score, and 4C Mortality scores were calculated on the initial day of ICU admission. Primary endpoints were all-cause mortality, ICU length of stay, and hospital length of stay. Results Initially, 62,881 patient encounters were assessed, and the cohort of 292 was selected based on the inclusion of the requisite values for each of the scoring systems. The median age was 56 +/- 14.93 years and 61% of patients were male. Mortality was defined as patients who expired or were discharged to hospice and was 78%. The different scoring systems were compared using logistic regression, receiver operating characteristic (ROC) curve, and area under the ROC curve (AUC) analysis to compare the accuracy of prediction of the mortality and length of stay. The multivariate analysis showed that SOFA, APACHE II, SAPS II, and 4C scores were all significant predictors of mortality. The SOFA score had the highest AUC, though the confidence intervals for all of the models overlap therefore one model could not be considered superior to any of the others. Linear regression was performed to evaluate the models' ability to predict ICU and hospital length of stay, and none of the tested systems were found to be significant predictors of length of stay. Conclusion The SOFA, APACHE II, ISARIC 4-C, and SAPS II scores all accurately predicted mortality in critically ill patients with COVID-19. The SOFA score trended to perform the best. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Monk et al.) |
| References: | PLoS One. 2016 Dec 22;11(12):e0168948. (PMID: 28006826) Diagnostics (Basel). 2022 May 03;12(5):. (PMID: 35626285) JAMA. 2016 Feb 23;315(8):801-10. (PMID: 26903338) Acta Med Acad. 2016 Nov;45(2):97-103. (PMID: 28000485) BMC Anesthesiol. 2020 Dec 2;20(1):296. (PMID: 33267777) Can Respir J. 2022 Mar 28;2022:5129314. (PMID: 35356088) J Emerg Crit Care Med. 2021 Jan;5:. (PMID: 34179689) Crit Care Res Pract. 2021 Jun 19;2021:5443083. (PMID: 34258059) BMC Infect Dis. 2021 Nov 22;21(1):1173. (PMID: 34809594) J Infect Public Health. 2020 Dec;13(12):1833-1839. (PMID: 32788073) Intensive Care Med. 1996 Jul;22(7):707-10. (PMID: 8844239) JAMA. 1993 Dec 22-29;270(24):2957-63. (PMID: 8254858) BMJ. 2020 Sep 9;370:m3339. (PMID: 32907855) Crit Care Med. 2006 May;34(5):1297-310. (PMID: 16540951) Thorax. 2022 Jun;77(6):606-615. (PMID: 34810237) Crit Care Med. 1985 Oct;13(10):818-29. (PMID: 3928249) |
| فهرسة مساهمة: | Keywords: acute physiology and chronic health evaluation (apache) ii; corona virus mortality scores; covid-19; intensive care unit; isaric 4c score; risk stratification; sequential organ failure assessment (sofa); simplified acute physiology score (saps) ii |
| تواريخ الأحداث: | Date Created: 20230329 Latest Revision: 20230330 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC10040236 |
| DOI: | 10.7759/cureus.35423 |
| PMID: | 36987484 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2168-8184 |
|---|---|
| DOI: | 10.7759/cureus.35423 |