دورية أكاديمية
Prevalence and grade of diabetic peripheral neuropathy among known diabetic patients in rural Uganda.
| العنوان: | Prevalence and grade of diabetic peripheral neuropathy among known diabetic patients in rural Uganda. |
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| المؤلفون: | Munyambalu DK; Department of Internal Medicine, Kampala International University-Teaching Hospital, Bushenyi, Uganda., Hildago I; Department of Clinical Chemistry Laboratory, Kampala International University-Teaching Hospital, Bushenyi, Uganda., Bafwa YT; Department of Internal Medicine, Kampala International University-Teaching Hospital, Bushenyi, Uganda., Lagoro CA; Department of Internal Medicine, Kampala International University-Teaching Hospital, Bushenyi, Uganda., Sikakulya FK; Department of General Surgery, Kampala International University-Teaching Hospital, Bushenyi, Uganda.; Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of Congo., Vahwere BM; Department of General Surgery, Kampala International University-Teaching Hospital, Bushenyi, Uganda., Dafiewhare E; Department of Internal Medicine, Kampala International University-Teaching Hospital, Bushenyi, Uganda., Martinez L; Department of Internal Medicine, Kampala International University-Teaching Hospital, Bushenyi, Uganda., Charles FA; Department of Internal Medicine, Kampala International University-Teaching Hospital, Bushenyi, Uganda.; Department of Internal Medicine, Mbarara University of Science and Technology, Mbarara, Uganda. |
| المصدر: | Frontiers in clinical diabetes and healthcare [Front Clin Diabetes Healthc] 2023 Jan 11; Vol. 3, pp. 1001872. Date of Electronic Publication: 2023 Jan 11 (Print Publication: 2022). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 9918266295306676 Publication Model: eCollection Cited Medium: Internet ISSN: 2673-6616 (Electronic) Linking ISSN: 26736616 NLM ISO Abbreviation: Front Clin Diabetes Healthc Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Lausanne : Frontiers Media SA, [2020]- |
| مستخلص: | Background: Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes mellitus (DM). Approximately 50% of diabetic patients are estimated to develop DPN, depending on disease duration and diabetic control. Early diagnosis of DPN will avoid complications, including non-traumatic lower limb amputation, which is considered the most debilitating complication, as well as significant psychological, social, and economical problems. There is a paucity of literature on DPN from rural Uganda. This study aimed to deliver the prevalence and grade of DPN among DM patients in rural Uganda. Methods: A cross-sectional study that recruited 319 known DM patients was conducted in an outpatient clinic and a diabetic clinic at Kampala International University-Teaching Hospital (KIU-TH), Bushenyi, Uganda, between December 2019 and March 2020. Questionnaires were used to obtain clinical and sociodemographic data, a neurological examination was carried out to assess the DPN, and a blood sample was collected from each participant (for random/fasting blood glucose and glycosylated hemoglobin analyses). Data were analyzed using Stata version 15.0. Results: The sample size was 319 participants. The mean age of study participants was 59.4 ± 14.6 years and there were 197 (61.8%) females. The prevalence of DPN was 65.8% (210/319) (95% CI 60.4% to 70.9%), and 44.8% of participants had mild DPN, 42.4% had moderate DPN, and 12.8% had severe DPN. Conclusion: The prevalence of DPN at KIU-TH was higher among DM patients and its stage might have a negative impact on the progression of Diabetes Mellitus. Therefore, clinicians should consider neurological examination as a routine during assessment of all DM patients especially in rural areas where resources and facilities are often limited so that complications related to Diabetic mellitus will be prevented. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Munyambalu, Hildago, Bafwa, Lagoro, Sikakulya, Vahwere, Dafiewhare, Martinez and Charles.) |
| References: | S Afr Med J. 2016 Dec 01;106(12):1190-1191. (PMID: 27917764) Pan Afr Med J. 2018 Nov 01;31:158. (PMID: 31086614) J Diabetes Investig. 2013 Jan;4(1):4-18. (PMID: 23550085) Diabetes Care. 1987 Jul-Aug;10(4):432-40. (PMID: 3622200) J Neurol Sci. 2015 Aug 15;355(1-2):108-12. (PMID: 26048049) Diabetes Care. 2013 Sep;36(9):2456-65. (PMID: 23970715) Pharmacol Res. 2014 Feb;80:21-35. (PMID: 24373831) J Clin Transl Endocrinol. 2017 Sep 20;10:9-14. (PMID: 29204366) Epidemiol Health. 2016 Mar 24;38:e2016011. (PMID: 27032459) Int J Low Extrem Wounds. 2006 Dec;5(4):244-9. (PMID: 17088600) Afr Health Sci. 2017 Jun;17(2):463-473. (PMID: 29062342) |
| فهرسة مساهمة: | Keywords: Kampala; Uganda; diabetes mellitus; diabetic peripheral neuropathy; prevalence and grade |
| تواريخ الأحداث: | Date Created: 20230330 Latest Revision: 20230331 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC10012102 |
| DOI: | 10.3389/fcdhc.2022.1001872 |
| PMID: | 36992747 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2673-6616 |
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| DOI: | 10.3389/fcdhc.2022.1001872 |