دورية أكاديمية
Diagnostic value of cerebrospinal fluid analysis in epileptic cats with unremarkable brain MRI or hippocampal signal changes only.
| العنوان: | Diagnostic value of cerebrospinal fluid analysis in epileptic cats with unremarkable brain MRI or hippocampal signal changes only. |
|---|---|
| المؤلفون: | Majercikova R; Clinical Unit of Internal Medicine Small Animals, Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria., Rütgen BC; Clinical Pathology, Department of Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria., Luckschander-Zeller N; Clinical Unit of Internal Medicine Small Animals, Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria., Lörincz BA; Clinical Unit of Diagnostic Imaging, Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria., Pakozdy A; Clinical Unit of Internal Medicine Small Animals, Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria. |
| المصدر: | Journal of feline medicine and surgery [J Feline Med Surg] 2023 Mar; Vol. 25 (3), pp. 1098612X231158573. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Country of Publication: England NLM ID: 100897329 Publication Model: Print Cited Medium: Internet ISSN: 1532-2750 (Electronic) Linking ISSN: 1098612X NLM ISO Abbreviation: J Feline Med Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2012- : London : Sage Original Publication: London ; Philadelphia : WB Saunders Co., |
| مواضيع طبية MeSH: | Epilepsy*/diagnostic imaging , Epilepsy*/veterinary , Cat Diseases*/diagnostic imaging, Cats ; Animals ; Retrospective Studies ; Seizures/veterinary ; Hippocampus/diagnostic imaging ; Magnetic Resonance Imaging/veterinary |
| مستخلص: | Objectives: Cerebrospinal fluid (CSF) analysis is used in the diagnostic investigation of cats with epileptic seizures. The aim of this retrospective study was to evaluate the diagnostic value of CSF analysis in cats with epileptic seizures that have unremarkable brain MRI or only hippocampal signal changes. Methods: Unremarkable brain MRI or MRI studies with signal alterations in the hippocampus only in cats with suspected epilepsy and CFS analysis performed at the Small Animal Internal Department or Diagnostic Imaging Department at Vetmeduni Vienna, Austria, between 2011 and 2017 were reviewed. Total nucleated cell count, total protein, blood contamination and cytology data from CSF analysis were evaluated. Results: In total, 87 cats were included. Seventy cats (80.5%) had unremarkable MRI, five (5.7%) had hippocampal signal changes with contrast enhancement and 12 (13.8%) had hippocampal signal changes without contrast enhancement. Overall, four cats (4.6%) had abnormalities on CSF analysis; all (100%) had an increased total nucleated cell count (22 cells/μl, 7 cells/μl, 6 cells/μl and 6 cells/μl, respectively), and no cat had increased total protein (100%), although in one cat total protein was not evaluated. Three of these cats had unremarkable MRI and one had hippocampal signal changes without contrast enhancement. The median duration of epileptic signs prior to the MRI study was 2 days. Conclusions and Relevance: Our results show that, in our cohort of epileptic cats with unremarkable brain MRI or with hippocampal signal changes, CSF analysis was usually normal. This should be considered before performing a CSF tap. |
| References: | Vet Radiol Ultrasound. 2007 Jul-Aug;48(4):323-7. (PMID: 17691630) Epileptic Disord. 2015 Dec;17(4):453-9. (PMID: 26575850) Vet Clin Pathol. 2009 Sep;38(3):392-6. (PMID: 19392761) Tierarztl Prax Ausg K Kleintiere Heimtiere. 2022 Mar;50(1):13-22. (PMID: 35235959) Vet Clin Pathol. 2006 Sep;35(3):315-20. (PMID: 16967416) Vet Clin Pathol. 2018 Sep;47(3):464-470. (PMID: 30011069) J Feline Med Surg. 2004 Dec;6(6):377-81. (PMID: 15546770) Vet Radiol Ultrasound. 2005 Nov-Dec;46(6):467-71. (PMID: 16396261) BMC Vet Res. 2015 Aug 28;11:182. (PMID: 26316133) Vet Rec. 2019 Nov 2;185(17):539. (PMID: 31409750) J Feline Med Surg. 2010 Dec;12(12):910-6. (PMID: 20822944) Epilepsia. 2004 Jun;45(6):695-714. (PMID: 15144438) J Vet Intern Med. 2022 Mar;36(2):679-693. (PMID: 35048412) J Am Vet Med Assoc. 2000 Jul 1;217(1):54-7. (PMID: 10909447) Aust Vet J. 2021 Jan;99(1-2):1-5. (PMID: 32893907) J Vet Intern Med. 2020 Nov;34(6):2582-2594. (PMID: 32974979) Vet J. 2010 Jun;184(3):290-7. (PMID: 19410487) Vet J. 2023 Jan;291:105941. (PMID: 36549606) Eur J Neurol. 2019 Jul;26(7):1006-1012. (PMID: 30719804) J Vet Intern Med. 2014 Mar-Apr;28(2):255-63. (PMID: 24438024) Vet Rec. 2010 Apr 17;166(16):497-8. (PMID: 20400742) Vet Clin Pathol. 2008 Sep;37(3):344-52. (PMID: 18761531) J Vet Intern Med. 2021 Mar;35(2):1008-1017. (PMID: 33559928) Epilepsia. 2006;47 Suppl 5:2-8. (PMID: 17239098) Vet Rec. 2017 Nov;181(18):479. (PMID: 29097567) Ann Neurol. 1981 Jan;9(1):81-4. (PMID: 7212671) Vet Radiol Ultrasound. 2008 Jul-Aug;49(4):343-9. (PMID: 18720764) Acta Vet Scand. 2015 Jul 28;57:41. (PMID: 26215252) Vet Radiol Ultrasound. 1999 Nov-Dec;40(6):588-95. (PMID: 10608685) Vet Radiol Ultrasound. 2008 Sep-Oct;49(5):467-71. (PMID: 18833957) J Feline Med Surg. 2011 Oct;13(10):687-93. (PMID: 21795088) Epilepsy Res. 2015 Aug;114:23-31. (PMID: 26088882) Funct Neurol. 2016 Apr-Jun;31(2):101-7. (PMID: 27358223) J Feline Med Surg. 2007 Apr;9(2):109-16. (PMID: 17052935) BMC Vet Res. 2016 Aug 11;12(1):165. (PMID: 27515840) |
| فهرسة مساهمة: | Keywords: Cerebrospinal fluid; epilepsy; hippocampus; seizure |
| تواريخ الأحداث: | Date Created: 20230330 Date Completed: 20230403 Latest Revision: 20240515 |
| رمز التحديث: | 20240515 |
| مُعرف محوري في PubMed: | PMC10812015 |
| DOI: | 10.1177/1098612X231158573 |
| PMID: | 36995228 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1532-2750 |
|---|---|
| DOI: | 10.1177/1098612X231158573 |