دورية أكاديمية
Post-ictal changes presenting as late pseudoprogression on MRI and PET in a patient with diffuse glioma: Case report and brief literature review.
| العنوان: | Post-ictal changes presenting as late pseudoprogression on MRI and PET in a patient with diffuse glioma: Case report and brief literature review. |
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| المؤلفون: | Nair SM; Department of Radiodiagnosis, Tata Memorial Centre, Homi Bhabha National Institute (HBNI), Mumbai, India., Sahu A; Department of Radiodiagnosis, Tata Memorial Centre, Homi Bhabha National Institute (HBNI), Mumbai, India., Dasgupta A; Department of Radiation Oncology, Tata Memorial Centre, Homi Bhabha National Institute (HBNI), Mumbai, India., Puranik A; Department of Nuclear Medicine, Homi Bhabha National Institute (HBNI), Mumbai, India., Gupta T; Department of Radiation Oncology, Tata Memorial Centre, Homi Bhabha National Institute (HBNI), Mumbai, India. |
| المصدر: | The neuroradiology journal [Neuroradiol J] 2024 Apr; Vol. 37 (2), pp. 229-233. Date of Electronic Publication: 2023 Mar 31. |
| نوع المنشور: | Case Reports; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Publications Country of Publication: United States NLM ID: 101295103 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2385-1996 (Electronic) Linking ISSN: 19714009 NLM ISO Abbreviation: Neuroradiol J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2015- : Thousand Oaks, CA : Sage Publications Original Publication: Bologna : Centauro |
| مواضيع طبية MeSH: | Brain Neoplasms*/diagnostic imaging , Brain Neoplasms*/therapy , Brain Neoplasms*/pathology , Glioma*/diagnostic imaging , Glioma*/therapy , Glioma*/pathology , Oligodendroglioma*/diagnostic imaging , Oligodendroglioma*/therapy, Humans ; Magnetic Resonance Imaging/methods ; Positron-Emission Tomography/methods ; Tumor Microenvironment |
| مستخلص: | Following completion of adjuvant radiation and chemotherapy imaging surveillance forms a major role in the management of diffuse gliomas. The primary role of imaging is to detect recurrences earlier than clinical symptomatology. Magnetic resonance imaging (MRI) is considered the gold standard in follow-up protocols owing to better soft tissue delineation and multiparametric nature. True recurrence can often mimic treatment-related changes, it is of paramount importance to differentiate between the two entities as the clinical course is divergent. Addition of functional sequences like perfusion, spectroscopy and metabolic imaging can provide further details into the microenvironment. In equivocal cases, a follow-up short interval imaging might be obtained to settle the diagnostic dilemma. Here, we present a patient with diagnosis of recurrent oligodendroglioma treated with adjuvant chemoradiation, presenting with seizures five years post-completion of chemotherapy for recurrence. On MRI, subtle new onset gyral thickening of the left frontal region with mild increase in perfusion and patchy areas of raised choline. FET-PET (fluoro-ethyltyrosine) showed an increased tumour-to-white matter (T/Wm) ratio favouring tumour recurrence. Based on discussion in a multi-disciplinary joint clinic, short interval follow-up MRI was undertaken at two months showing decrease in gyral thickening and resolution of enhancing areas in left frontal lobe. Repeat imaging one year later demonstrated stable disease status without further new imaging findings. Given the changes resolving completely without any anti-tumoral intervention, we conclude this to be peri-ictal pseudoprogression, being the second such case described in India. Competing Interests: Declaration of conflicting interestThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
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| فهرسة مساهمة: | Keywords: MRI; glioma; post-ictal |
| تواريخ الأحداث: | Date Created: 20230331 Date Completed: 20240320 Latest Revision: 20240330 |
| رمز التحديث: | 20240330 |
| مُعرف محوري في PubMed: | PMC10973818 |
| DOI: | 10.1177/19714009231166105 |
| PMID: | 37002537 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2385-1996 |
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| DOI: | 10.1177/19714009231166105 |