دورية أكاديمية
Prognostic Factors and Intensive Care Outcome in Post-Transplant Phase of Hematopoietic Stem Cell Transplantation: Intensive Care Outcome in Hematopoietic Stem Cell Transplantation.
| العنوان: | Prognostic Factors and Intensive Care Outcome in Post-Transplant Phase of Hematopoietic Stem Cell Transplantation: Intensive Care Outcome in Hematopoietic Stem Cell Transplantation. |
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| المؤلفون: | Mutlu YG; Department of Hematology, Istanbul Medipol University, Istanbul, Turkey., Aydin BB; Department of Hematology, Istanbul Medipol University, Istanbul, Turkey., Erdogan C; Department of Anesthesiology, Istanbul Medipol University, Istanbul, Turkey., Kizilaslan D; Department of Anesthesiology, Istanbul Medipol University, Istanbul, Turkey., Beköz HS; Department of Hematology, Istanbul Medipol University, Istanbul, Turkey., Gemici A; Department of Hematology, Istanbul Medipol University, Istanbul, Turkey., Kaynar L; Department of Hematology, Istanbul Medipol University, Istanbul, Turkey., Sevindik ÖG; Department of Hematology, Istanbul Medipol University, Istanbul, Turkey. |
| المصدر: | Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion [Indian J Hematol Blood Transfus] 2023 Apr; Vol. 39 (2), pp. 167-172. Date of Electronic Publication: 2022 Oct 11. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Indian Society of Hematology and Blood Transfusion Country of Publication: India NLM ID: 9425818 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0971-4502 (Print) Linking ISSN: 09714502 NLM ISO Abbreviation: Indian J Hematol Blood Transfus Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: [Mumbai] : Springer India : Indian Society of Hematology and Blood Transfusion Original Publication: Bombay : Indian Society of Hematology and Blood Transfusion |
| مستخلص: | Introduction: To identify new clinical and biologic parameters associated with short-term survival in allogeneic or autologous hematopoietic stem cell transplantation (HSCT) patients who were admitted to the intensive care unit (ICU) during their post-transplant period. Materials and Methods: 40 patients who were admitted to the ICU in our center during their post-transplant period were evaluated retrospectively between Jan 2014 - Jun 2021. Baseline patient characteristics before the transplant, reasons for ICU admissions, laboratory and clinical findings, supportive treatment in ICU and short-term survival were analyzed. Results: We found 8.8% ICU admission rate in all patient group (n = 450). Mortality rate of the patients who were admitted to ICU was 75%. Invasive mechanic ventilation, need for vasopressor, heart rate was significantly different between survivor and non-survivor group (p = 0.001, p = 0.001, p = 0.004). Elevated INR was associated with poor survival on ICU (p = 0.033). APACHE II score was an independent predictor of ICU mortality (p = 0.045). Conclusion: Despite the recent advances in transplant conditioning protocols, prophylaxis strategies and improvements of management in ICU, overall survival for HSCT patients in ICU is still poor. In this study INR level was described as a new prognostic factor in ICU for first time in the literature. Competing Interests: Conflict of interestAll authors declare no conflict of interest that may have influences either the conduct or the presentation of the research. (© The Author(s), under exclusive licence to Indian Society of Hematology and Blood Transfusion 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.) |
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| فهرسة مساهمة: | Keywords: critically ill; mortality; transplantation |
| تواريخ الأحداث: | Date Created: 20230403 Latest Revision: 20240402 |
| رمز التحديث: | 20240402 |
| مُعرف محوري في PubMed: | PMC10064358 |
| DOI: | 10.1007/s12288-022-01575-5 |
| PMID: | 37006979 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 0971-4502 |
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| DOI: | 10.1007/s12288-022-01575-5 |