دورية أكاديمية
Benefit and risk evaluation of quinapril hydrochloride.
| العنوان: | Benefit and risk evaluation of quinapril hydrochloride. |
|---|---|
| المؤلفون: | Barkhordarian M; Department of Internal Medicine, Hackensack Meridian Health - Palisades Medical Center, North Bergen, NJ, USA., Lawrence JA; Department of Internal Medicine, Ross University School of Medicine, Largo, MD, USA., Ulusan S; Department of Internal Medicine, Suleyman Demirel University School of Medicine, Isparta, Turkey., Erbay MI; Cerrahpasa School of Medicine Istanbul, Istanbul University Cerrahpasa, Istanbul, Turkey., Aronow WS; Department of Cardiology, Westchester Medical Center, New York, NY, USA., Gupta R; Lehigh Valley Heart Institute, Lehigh Valley Health Network, Allentown, PA, USA. |
| المصدر: | Expert opinion on drug safety [Expert Opin Drug Saf] 2023 Apr; Vol. 22 (4), pp. 271-277. Date of Electronic Publication: 2023 Apr 17. |
| نوع المنشور: | Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 101163027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-764X (Electronic) Linking ISSN: 14740338 NLM ISO Abbreviation: Expert Opin Drug Saf Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2015- : Abingdon, Oxford : Taylor & Francis Original Publication: London : Ashley Publications, c2002- |
| مواضيع طبية MeSH: | Tetrahydroisoquinolines*/adverse effects , Hypertension* , Heart Failure*, Humans ; Aged ; Quinapril ; Isoquinolines/adverse effects ; Antihypertensive Agents/adverse effects ; Angiotensin-Converting Enzyme Inhibitors/adverse effects |
| مستخلص: | Introduction: Angiotensin-converting enzyme (ACE) inhibitors are a mainstay of antihypertensive therapy. Quinapril hydrochloride, a less commonly used, and less-studied ACE inhibitor has been approved for its primary use in hypertension. Studies also indicate its off-label use for congestive heart failure and diabetic nephropathy. The ANDI and TREND trials have been pivotal in demonstrating the effectiveness of quinapril. Areas Covered: The authors conducted a review of the literature analyzing the clinical efficacy and safety profile of quinapril. This review discusses the development of quinapril, provides an updated summary of the indications and contraindications, and presents a comparison with other ACE inhibitors. Expert Opinion: Quinapril is a safe and well-tolerated antihypertensive medication with a favorable safety profile compared to other ACE inhibitors. However, a lack of ample recent clinical trials and post-marketing data investigating the efficacy of quinapril in large cohorts has resulted in limited use in clinical practice. Quinapril may be an effective antihypertensive option for elderly populations as well as those who cannot tolerate the side effects profiles of other ACE inhibitors and as an additional treatment option for patients with heart failure with preserved ejection fraction. |
| فهرسة مساهمة: | Keywords: ACE inhibitors; Hypertension; Quinapril hydrochloride; efficacy; safety |
| المشرفين على المادة: | RJ84Y44811 (Quinapril) 0 (Tetrahydroisoquinolines) 0 (Isoquinolines) 0 (Antihypertensive Agents) 0 (Angiotensin-Converting Enzyme Inhibitors) |
| تواريخ الأحداث: | Date Created: 20230415 Date Completed: 20230522 Latest Revision: 20230522 |
| رمز التحديث: | 20230522 |
| DOI: | 10.1080/14740338.2023.2203481 |
| PMID: | 37060355 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1744-764X |
|---|---|
| DOI: | 10.1080/14740338.2023.2203481 |