تقرير
ANTI-NMDA-R encephalitis: case report.
العنوان: | ANTI-NMDA-R encephalitis: case report. |
---|---|
المؤلفون: | Tosunoğlu B; Department of Neurology, Ankara Training and Research Hospital, Turkey Abstract., Güneş HN; Department of Neurology, Ankara Training and Research Hospital, Turkey Abstract., Kına HM; Department of Neurology, Ankara Training and Research Hospital, Turkey Abstract., Çokal BG; Department of Neurology, Ankara Training and Research Hospital, Turkey Abstract. |
المصدر: | Postepy psychiatrii neurologii [Postep Psychiatr Neurol] 2022 Sep; Vol. 31 (3), pp. 138-140. Date of Electronic Publication: 2022 Oct 22. |
نوع المنشور: | Case Reports |
اللغة: | English |
بيانات الدورية: | Publisher: Instytut Psychiatrii I Neurologii Country of Publication: Poland NLM ID: 9434378 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2720-5371 (Electronic) Linking ISSN: 12302813 NLM ISO Abbreviation: Postep Psychiatr Neurol Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Publication: Warszawa : Instytut Psychiatrii I Neurologii Original Publication: Warszawa : Instytut, |
مستخلص: | Purpose: Anti-N-methyl-D-aspartate receptor encephalitis (NMDA-R) is the most common among autoimmune encephalitis caused by antibodies developed against surface antigens. It was first identified in 2007 as presenting with seizures, autonomic dysfunction and movement disorders, in addition to acute or subacute onset of neuropsychiatric symptoms. Multifocal, nonspecific white matter lesions can be seen on cranial magnetic resonance imaging (MRI). Since paraneoplasia is usually found in the etiology, malignancy should be screened in patients with NMDA-R encephalitis. Case Description: In our case, a 48-year-old patient is presented who has been diagnosed with anti-NMDA-R encephalitis during the examinations, complaining of numbness on the left side of his face, seizures, imbalance, excessive talkativeness and insomnia. Comment: Autoimmune encephalitis should be considered in patients with suspected autoimmune encephalitis, which takes severe clinical course and fails to respond to treatment adequately; NMDA receptor antibodies and other autoantibody tests should be requested, malignancy screening should be performed and treatment should be started in the early period. Competing Interests: Absent. (Copyright © 2022 Institute of Psychiatry and Neurology.) |
References: | Lancet Neurol. 2013 Feb;12(2):157-65. (PMID: 23290630) Exp Ther Med. 2015 Oct;10(4):1283-1292. (PMID: 26622479) Front Neurol. 2018 Sep 05;9:706. (PMID: 30233481) BJPsych Bull. 2015 Feb;39(1):19-23. (PMID: 26191419) Front Neurol. 2019 Nov 05;10:1086. (PMID: 31749755) Crit Care Med. 2018 Sep;46(9):1514-1521. (PMID: 29927776) J Neurosci. 2010 Apr 28;30(17):5866-75. (PMID: 20427647) Neurologia. 2007 Oct;22(8):526-37. (PMID: 18000762) Lancet Neurol. 2019 Nov;18(11):1045-1057. (PMID: 31326280) |
فهرسة مساهمة: | Keywords: encephalitis; paraneoplasia; seizure |
تواريخ الأحداث: | Date Created: 20230421 Latest Revision: 20230422 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC9946364 |
DOI: | 10.5114/ppn.2022.120492 |
PMID: | 37082226 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2720-5371 |
---|---|
DOI: | 10.5114/ppn.2022.120492 |