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A delve into the pharmacological targets and biological mechanisms of Paederia foetida Linn.: a rather invaluable traditional medicinal plant.

التفاصيل البيبلوغرافية
العنوان: A delve into the pharmacological targets and biological mechanisms of Paederia foetida Linn.: a rather invaluable traditional medicinal plant.
المؤلفون: Sarma MK; Department of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Assam Science and Technology University, Guwahati, 781 017, Assam, India., Saha D; Department of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Assam Science and Technology University, Guwahati, 781 017, Assam, India. drdsaha@gips-guwahati.ac.in., Das BK; Department of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Assam Science and Technology University, Guwahati, 781 017, Assam, India., Das T; Department of Pharmacology, Girijananda Chowdhury Institute of Pharmaceutical Science, Assam Science and Technology University, Guwahati, 781 017, Assam, India., Azizov S; Laboratory of Biological Active Macromolecular Systems, Institute of Bioorganic Chemistry, Uzbekistan Academy of Sciences, 100125, Tashkent, Uzbekistan.; Faculty of Life Sciences, Pharmaceutical Technical University, 100084, Tashkent, Uzbekistan., Kumar D; Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, 173229, India. guptadeepak002@gmail.com.
المصدر: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2023 Oct; Vol. 396 (10), pp. 2217-2240. Date of Electronic Publication: 2023 Apr 26.
نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Berlin, New York, Springer Verlag.
مواضيع طبية MeSH: Plants, Medicinal* , Rubiaceae*, Plant Extracts/pharmacology ; Anti-Inflammatory Agents ; Antioxidants/pharmacology ; Phytochemicals ; Phytotherapy
مستخلص: Drug development from herbal medicines or botanical sources is believed to have a prominent role in the exploration of novel counteractive drugs that has sparked much interest in recent times. Paederia foetida is one such medicinal plant used in both traditional and folkloric medicine. Several parts of the herb are locally utilised as a natural curative agent for several ailments since time immemorial. Paederia foetida indeed possesses anti-diabetic, anti-hyperlipidaemic, antioxidant, nephro-protective, anti-inflammatory, antinociceptive, antitussive, thrombolytic, anti-diarrhoeal, sedative-anxiolytic, anti-ulcer, hepatoprotective activity, anthelmintic and anti-diarrhoeal activity. Furthermore, growing evidence shows many of its active constituents to be effective in cancer, inflammatory diseases, wound healing and spermatogenesis as well. These investigations shed light on possible pharmacological targets and attempts to establish a mechanism of action for these pharmacological effects. These findings contrast the significance of this medicinal plant for further research and for the exploration of novel counteractive drugs to establish a mechanism of action before being employed to healthcare. Pharmacological activities of Paederia foetida and their mechanism of action.
(© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
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فهرسة مساهمة: Keywords: Biological mechanism; Medicinal plant; Paederia foetida; Pharmacological targets
المشرفين على المادة: 0 (Plant Extracts)
0 (Anti-Inflammatory Agents)
0 (Antioxidants)
0 (Phytochemicals)
تواريخ الأحداث: Date Created: 20230426 Date Completed: 20230913 Latest Revision: 20230922
رمز التحديث: 20230922
DOI: 10.1007/s00210-023-02496-4
PMID: 37099165
قاعدة البيانات: MEDLINE
الوصف
تدمد:1432-1912
DOI:10.1007/s00210-023-02496-4