دورية أكاديمية
Evaluation of the Hematological Patterns from Up to 985 Days of Long COVID: A Cross-Sectional Study.
العنوان: | Evaluation of the Hematological Patterns from Up to 985 Days of Long COVID: A Cross-Sectional Study. |
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المؤلفون: | Galúcio VCA; Center for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil., Menezes DC; Center for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil., Lima PDL; Center for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil., Palácios VRDCM; Center for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil., Vasconcelos PFDC; Center for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil., Quaresma JAS; Center for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil.; School of Medicine, São Paulo University (USP), São Paulo 01246903, Brazil.; Tropical Medicine Center, Federal University of Pará (UFPA), Belém 66055-240, Brazil., Falcão LFM; Center for Biological Health Sciences, State University of Pará (UEPA), Belém 66087-670, Brazil.; School of Medicine, São Paulo University (USP), São Paulo 01246903, Brazil. |
المصدر: | Viruses [Viruses] 2023 Mar 29; Vol. 15 (4). Date of Electronic Publication: 2023 Mar 29. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI |
مواضيع طبية MeSH: | COVID-19*, Humans ; Cross-Sectional Studies ; Erythrocyte Indices ; Hematologic Tests ; Erythrocytes ; Post-Acute COVID-19 Syndrome |
مستخلص: | Long COVID affects many individuals following acute coronavirus disease 2019 (COVID-19), and hematological changes can persist after the acute COVID-19 phase. This study aimed to evaluate these hematological laboratory markers, linking them to clinical findings and long-term outcomes in patients with long COVID. This cross-sectional study selected participants from a 'long COVID' clinical care program in the Amazon region. Clinical data and baseline demographics were obtained, and blood samples were collected to quantify erythrogram-, leukogram-, and plateletgram-related markers. Long COVID was reported for up to 985 days. Patients hospitalized in the acute phase had higher mean red/white blood cell, platelet, and plateletcrit levels and red blood cell distribution width. Furthermore, hematimetric parameters were higher in shorter periods of long COVID than in longer periods. Patients with more than six concomitant long COVID symptoms had a higher white blood cell count, a shorter prothrombin time (PT), and increased PT activity. Our results indicate there may be a compensatory mechanism for erythrogram-related markers within 985 days of long COVID. Increased levels of leukogram-related markers and coagulation activity were observed in the worst long COVID groups, indicating an exacerbated response after the acute disturbance, which is uncertain and requires further investigation. |
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فهرسة مساهمة: | Keywords: blood cell count; erythrocyte indices; hematological tests; laboratory markers; long COVID |
تواريخ الأحداث: | Date Created: 20230428 Date Completed: 20230501 Latest Revision: 20230501 |
رمز التحديث: | 20230501 |
مُعرف محوري في PubMed: | PMC10142608 |
DOI: | 10.3390/v15040879 |
PMID: | 37112859 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1999-4915 |
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DOI: | 10.3390/v15040879 |