دورية أكاديمية
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Epidemiologic and Clinical Characteristics of Human Bocavirus Infection in Children with or without Acute Gastroenteritis in Acre, Northern Brazil.

التفاصيل البيبلوغرافية
العنوان: Epidemiologic and Clinical Characteristics of Human Bocavirus Infection in Children with or without Acute Gastroenteritis in Acre, Northern Brazil.
المؤلفون: Trindade FTB; Postgraduate Program in Epidemiology and Health Surveillance, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Ramos ESF; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Lobo PS; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Cardoso JF; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Penha Júnior ET; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Bezerra DAM; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Neves MAO; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Andrade JAA; Secretaria de Estado da Saúde do Pará-SESPA, Belém 66093-677, PA, Brazil., Moraes Silva MC; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Mascarenhas JDP; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Guerra SFS; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil., Soares LS; Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde e Ambiente-IEC/SVSA/MS, Ananindeua 67030-000, PA, Brazil.
المصدر: Viruses [Viruses] 2023 Apr 21; Vol. 15 (4). Date of Electronic Publication: 2023 Apr 21.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI
مواضيع طبية MeSH: Human bocavirus*/genetics , Parvoviridae Infections*/epidemiology , Gastroenteritis*/epidemiology , Bocavirus* , Respiratory Tract Infections*, Humans ; Child ; Infant ; Child, Preschool ; Brazil/epidemiology ; Diarrhea/epidemiology ; Feces ; Acute Disease
مستخلص: Human bocavirus (HBoV) is an emerging virus detected around the world that may be associated with cases of acute gastroenteritis (AGE). However, its contribution to AGE has not been elucidated. This study aimed to describe the frequency, clinical features, and HBoV species circulation in children up to 5 years with or without AGE symptoms in Acre, Northern Brazil. A total of 480 stool samples were collected between January and December 2012. Fecal samples were used for extraction, nested PCR amplification, and sequencing for genotyping. Statistical analysis was applied to verify the association between epidemiological and clinical characteristics. Overall, HBoV-positivity was 10% (48/480), with HBoV-positive rates of 8.4% (19/226) and 11.4% (29/254) recorded in diarrheic and non-diarrheic children, respectively. The most affected children were in the age group ranging between 7 and 24 months (50%). HBoV infection was more frequent in children who live in urban areas (85.4%), use water from public networks (56.2%), and live with adequate sewage facilities (50%). Co-detection with other enteric viruses was 16.7% (8/48) and the most prevalent coinfection was RVA+ HBoV (50%, 4/8). HBoV-1 was the most frequent species detected in diarrheic and non-diarrheic children, responsible for 43.8% (21/48) of cases, followed by HBoV-3 (29.2%, 14/48) and HBoV-2 (25%, 12/48). In this study, HBoV infection was not always associated with AGE, as most HBoV cases belonged to the non-diarrheal group. Future studies are warranted in order to determine the role of HBoV in causing acute diarrhea disease.
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فهرسة مساهمة: Keywords: acute gastroenteritis; children; human bocaparvovirus
تواريخ الأحداث: Date Created: 20230428 Date Completed: 20230501 Latest Revision: 20230501
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10143463
DOI: 10.3390/v15041024
PMID: 37113004
قاعدة البيانات: MEDLINE
الوصف
تدمد:1999-4915
DOI:10.3390/v15041024