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Ancient human DNA recovered from a Palaeolithic pendant.

التفاصيل البيبلوغرافية
العنوان: Ancient human DNA recovered from a Palaeolithic pendant.
المؤلفون: Essel E; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. elena_essel@eva.mpg.de., Zavala EI; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.; Department of Biology, San Francisco State University, San Francisco, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Schulz-Kornas E; Department of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany., Kozlikin MB; Institute of Archaeology and Ethnography, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia., Fewlass H; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany., Vernot B; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany., Shunkov MV; Institute of Archaeology and Ethnography, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia., Derevianko AP; Institute of Archaeology and Ethnography, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia., Douka K; Department of Evolutionary Anthropology, Faculty of Life Sciences, University of Vienna, Vienna, Austria.; Human Evolution and Archaeological Sciences (HEAS) Research Network, University of Vienna, Vienna, Austria., Barnes I; Earth Sciences Department, Natural History Museum, London, UK., Soulier MC; Maison de la Recherche, Université de Toulouse-Jean Jaurès, CNRS UMR 5608 TRACES, Toulouse, France., Schmidt A; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany., Szymanski M; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany., Tsanova T; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.; Department of Chemistry 'Giacomo Ciamician', Alma Mater Studiorum, University of Bologna, Bologna, Italy., Sirakov N; National Institute of Archaeology with Museum, Bulgarian Academy of Sciences, Sofia, Bulgaria., Endarova E; National Museum of History, Sofia, Bulgaria., McPherron SP; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany., Hublin JJ; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.; Chaire de Paléoanthropologie, Collège de France, Paris, France., Kelso J; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany., Pääbo S; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany., Hajdinjak M; Ancient Genomics Laboratory, The Francis Crick Institute, London, UK.; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany., Soressi M; Faculty of Archaeology, Leiden University, Leiden, The Netherlands. m.a.soressi@arch.leidenuniv.nl., Meyer M; Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. mmeyer@eva.mpg.de.
المصدر: Nature [Nature] 2023 Jun; Vol. 618 (7964), pp. 328-332. Date of Electronic Publication: 2023 May 03.
نوع المنشور: Historical Article; Journal Article
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
أسماء مطبوعة: Publication: Basingstoke : Nature Publishing Group
Original Publication: London, Macmillan Journals ltd.
مواضيع طبية MeSH: Bone and Bones*/chemistry , DNA, Ancient*/analysis , DNA, Ancient*/isolation & purification , Tooth*/chemistry, Animals ; Female ; Humans ; Archaeology/methods ; Deer/genetics ; DNA, Mitochondrial/analysis ; DNA, Mitochondrial/isolation & purification ; History, Ancient ; Siberia ; Caves ; Russia
مستخلص: Artefacts made from stones, bones and teeth are fundamental to our understanding of human subsistence strategies, behaviour and culture in the Pleistocene. Although these resources are plentiful, it is impossible to associate artefacts to specific human individuals 1 who can be morphologically or genetically characterized, unless they are found within burials, which are rare in this time period. Thus, our ability to discern the societal roles of Pleistocene individuals based on their biological sex or genetic ancestry is limited 2-5 . Here we report the development of a non-destructive method for the gradual release of DNA trapped in ancient bone and tooth artefacts. Application of the method to an Upper Palaeolithic deer tooth pendant from Denisova Cave, Russia, resulted in the recovery of ancient human and deer mitochondrial genomes, which allowed us to estimate the age of the pendant at approximately 19,000-25,000 years. Nuclear DNA analysis identifies the presumed maker or wearer of the pendant as a female individual with strong genetic affinities to a group of Ancient North Eurasian individuals who lived around the same time but were previously found only further east in Siberia. Our work redefines how cultural and genetic records can be linked in prehistoric archaeology.
(© 2023. The Author(s).)
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المشرفين على المادة: 0 (DNA, Ancient)
0 (DNA, Mitochondrial)
تواريخ الأحداث: Date Created: 20230503 Date Completed: 20230613 Latest Revision: 20230613
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10247382
DOI: 10.1038/s41586-023-06035-2
PMID: 37138083
قاعدة البيانات: MEDLINE
الوصف
تدمد:1476-4687
DOI:10.1038/s41586-023-06035-2