دورية أكاديمية
أعرض في EDS

Endoscopic radiofrequency Stretta therapy reduces proton pump inhibitor dependency and the need for anti-reflux surgery for refractory gastroesophageal reflux disease.

التفاصيل البيبلوغرافية
العنوان: Endoscopic radiofrequency Stretta therapy reduces proton pump inhibitor dependency and the need for anti-reflux surgery for refractory gastroesophageal reflux disease.
المؤلفون: Joel A; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Konjengbam A; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Viswanath Y; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Kourounis G; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Hammond E; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Frank H; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Kuttuva S; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Mbarushimana S; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Hidayat H; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Thulasiraman S; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK.
المصدر: Clinical endoscopy [Clin Endosc] 2024 Jan; Vol. 57 (1), pp. 58-64. Date of Electronic Publication: 2023 May 02.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Korean Society of Gastrointestinal Endoscopy Country of Publication: Korea (South) NLM ID: 101576886 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2234-2400 (Print) Linking ISSN: 22342400 NLM ISO Abbreviation: Clin Endosc Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Seoul : Korean Society of Gastrointestinal Endoscopy
مستخلص: Background/aims: Radiofrequency treatment of the gastroesophageal junction using the Stretta procedure for treating gastroesophageal reflux disease (GERD) is observed to improve the symptoms and proton pump inhibitor (PPI) dependence and reduce the need for anti-reflux operations. As one of the largest studies in Europe, we evaluated the clinical outcomes of Stretta in patients with medically refractory GERD.
Methods: A tertiary UK center evaluated all patients with refractory GERD who underwent Stretta between 2014 and 2022. Patients and primary care professionals were contacted to obtain information regarding the initiation of PPI and reintervention after Stretta.
Results: Of the 195 patients (median age, 55 years; 116 women [59.5%]) who underwent Stretta, PPI-free period (PFP) data were available for 144 (73.8%) patients. Overall, 66 patients (45.8%) did not receive PPI after a median follow-up of 55 months. Six patients (3.1%) underwent further interventions. The median PFP after Stretta was 41 months. There was a significant negative correlation between PFP and age (p=0.007), with no differences between sexes (p=0.96). Patients younger than 55 years of age had a longer PFP than their older counterparts (p=0.005). Younger males had a significantly longer PFP than older males (p=0.021). However, this was not observed in the female cohort (p=0.09) or between the younger men and women (p=0.66).
Conclusion: Our findings suggest that Stretta is a safe and feasible option for treating refractory GERD, especially in younger patients. It prevents further anti-reflux interventions in most patients and increases the lead-time to surgery in patients with refractory GERD.
التعليقات: Comment in: Clin Endosc. 2024 Jan;57(1):48-50. (PMID: 38204168)
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فهرسة مساهمة: Keywords: Fundoplicatio; Gastrooesophageal reflux; Proton pump inhibitors; Radiofrequency therapy
تواريخ الأحداث: Date Created: 20230509 Latest Revision: 20240204
رمز التحديث: 20240205
مُعرف محوري في PubMed: PMC10834287
DOI: 10.5946/ce.2023.026
PMID: 37157958
قاعدة البيانات: MEDLINE
الوصف
تدمد:2234-2400
DOI:10.5946/ce.2023.026