دورية أكاديمية
Endoscopic radiofrequency Stretta therapy reduces proton pump inhibitor dependency and the need for anti-reflux surgery for refractory gastroesophageal reflux disease.
العنوان: | Endoscopic radiofrequency Stretta therapy reduces proton pump inhibitor dependency and the need for anti-reflux surgery for refractory gastroesophageal reflux disease. |
---|---|
المؤلفون: | Joel A; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Konjengbam A; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Viswanath Y; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Kourounis G; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Hammond E; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Frank H; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Kuttuva S; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Mbarushimana S; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Hidayat H; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK., Thulasiraman S; Department of General and Upper Gastrointestinal Surgery, James Cook University Hospital, Cleveland, UK. |
المصدر: | Clinical endoscopy [Clin Endosc] 2024 Jan; Vol. 57 (1), pp. 58-64. Date of Electronic Publication: 2023 May 02. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Korean Society of Gastrointestinal Endoscopy Country of Publication: Korea (South) NLM ID: 101576886 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2234-2400 (Print) Linking ISSN: 22342400 NLM ISO Abbreviation: Clin Endosc Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Seoul : Korean Society of Gastrointestinal Endoscopy |
مستخلص: | Background/aims: Radiofrequency treatment of the gastroesophageal junction using the Stretta procedure for treating gastroesophageal reflux disease (GERD) is observed to improve the symptoms and proton pump inhibitor (PPI) dependence and reduce the need for anti-reflux operations. As one of the largest studies in Europe, we evaluated the clinical outcomes of Stretta in patients with medically refractory GERD. Methods: A tertiary UK center evaluated all patients with refractory GERD who underwent Stretta between 2014 and 2022. Patients and primary care professionals were contacted to obtain information regarding the initiation of PPI and reintervention after Stretta. Results: Of the 195 patients (median age, 55 years; 116 women [59.5%]) who underwent Stretta, PPI-free period (PFP) data were available for 144 (73.8%) patients. Overall, 66 patients (45.8%) did not receive PPI after a median follow-up of 55 months. Six patients (3.1%) underwent further interventions. The median PFP after Stretta was 41 months. There was a significant negative correlation between PFP and age (p=0.007), with no differences between sexes (p=0.96). Patients younger than 55 years of age had a longer PFP than their older counterparts (p=0.005). Younger males had a significantly longer PFP than older males (p=0.021). However, this was not observed in the female cohort (p=0.09) or between the younger men and women (p=0.66). Conclusion: Our findings suggest that Stretta is a safe and feasible option for treating refractory GERD, especially in younger patients. It prevents further anti-reflux interventions in most patients and increases the lead-time to surgery in patients with refractory GERD. |
التعليقات: | Comment in: Clin Endosc. 2024 Jan;57(1):48-50. (PMID: 38204168) |
References: | Dermatol Clin. 1993 Oct;11(4):749-57. (PMID: 8222358) Surg Endosc. 2017 Dec;31(12):4865-4882. (PMID: 28233093) Dig Dis Sci. 2022 May;67(5):1455-1468. (PMID: 35258754) Medicine (Baltimore). 2020 Jan;99(3):e18610. (PMID: 32011441) Gastrointest Endosc. 2007 Mar;65(3):367-72. (PMID: 17321232) Clin Endosc. 2021 Jul;54(4):451-452. (PMID: 34261209) Gastrointest Endosc. 2003 Jan;57(1):17-22. (PMID: 12518124) Trends Pharmacol Sci. 2011 Apr;32(4):258-64. (PMID: 21429600) Br J Surg. 2009 Feb;96(2):128-36. (PMID: 19160349) J Neurogastroenterol Motil. 2021 Oct 30;27(4):453-481. (PMID: 34642267) Gastroenterol Hepatol (N Y). 2020 Apr;16(4):196-205. (PMID: 34035721) Surg Laparosc Endosc Percutan Tech. 2012 Aug;22(4):283-8. (PMID: 22874675) Gastrointest Endosc Clin N Am. 2003 Jan;13(1):135-45. (PMID: 12797433) Surgery. 2015 Jan;157(1):126-36. (PMID: 25262216) Gastroenterology. 2003 Sep;125(3):668-76. (PMID: 12949712) World J Gastroenterol. 2014 Jun 28;20(24):7730-8. (PMID: 24976710) Gastroenterol Res Pract. 2014;2014:531907. (PMID: 24959175) BMC Gastroenterol. 2014 Oct 10;14:178. (PMID: 25304252) Gut. 2014 Jun;63(6):871-80. (PMID: 23853213) Endosc Int Open. 2021 Nov 12;9(11):E1740-E1751. (PMID: 34790538) Am J Gastroenterol. 2006 Sep;101(9):2128-38. (PMID: 16848807) Aliment Pharmacol Ther. 2011 Feb;33(4):442-54. (PMID: 21138458) BMC Gastroenterol. 2020 May 27;20(1):162. (PMID: 32460696) Surg Endosc. 2014 Aug;28(8):2323-33. (PMID: 24562599) Am J Gastroenterol. 2012 Feb;107(2):222-30. (PMID: 22108449) World J Gastroenterol. 2011 Oct 21;17(39):4429-33. (PMID: 22110270) Surg Endosc. 2010 Apr;24(4):818-25. (PMID: 19730952) Gastroenterology. 2019 Jan;156(1):254-272.e11. (PMID: 30315778) Gastrointest Endosc. 2000 Jul;52(1):81-6. (PMID: 10882969) Front Med (Lausanne). 2021 Nov 01;8:765061. (PMID: 34790683) Clin Endosc. 2021 Jul;54(4):542-547. (PMID: 33761229) Frontline Gastroenterol. 2019 Apr;10(2):113-119. (PMID: 31205650) Acta Otorhinolaryngol Ital. 2006 Oct;26(5):241-6. (PMID: 17345925) Aliment Pharmacol Ther. 2008 Nov 1;28(9):1147-58. (PMID: 18616516) JAMA Surg. 2016 Jan;151(1):73-8. (PMID: 26629969) Gastrointest Endosc. 2002 Feb;55(2):149-56. (PMID: 11818914) |
فهرسة مساهمة: | Keywords: Fundoplicatio; Gastrooesophageal reflux; Proton pump inhibitors; Radiofrequency therapy |
تواريخ الأحداث: | Date Created: 20230509 Latest Revision: 20240204 |
رمز التحديث: | 20240205 |
مُعرف محوري في PubMed: | PMC10834287 |
DOI: | 10.5946/ce.2023.026 |
PMID: | 37157958 |
قاعدة البيانات: | MEDLINE |
كن أول من يترك تعليقا!