دورية أكاديمية
Physicochemical characterization and cancer cell antiproliferative effect of silver-doped magnesia nanoparticles.
العنوان: | Physicochemical characterization and cancer cell antiproliferative effect of silver-doped magnesia nanoparticles. |
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المؤلفون: | Al-Fahdawi MQ; Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia., Aldoghachi AF; Faculty of Medicine and Health Sciences, University Putra Malaysia, UPM, Serdang, 43300, Malaysia.; Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Cheras, 43000, Malaysia., Alhassan FH; Department of Applied Chemistry and Technology, College of Science and Arts, Alkamel University of Jeddah, Jeddah, 21589, Saudi Arabia.; Department of Nanoscience and Nanotechnology, Africa City of Technology, Khartoum Bahari, Khartoum, Sudan., Al-Doghachi FAJ; Department of Chemistry, Faculty of Science, University of Basra, Basra, Iraq., Alshwyeh HA; Department of Biology, College of Science, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia.; Basic & Applied Scientific Research Center, College of Science, Imam Abdulrahman Bin Faisal University, Dammam, 31441, Saudi Arabia., Rasedee A; Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.; Department of Veterinary Laboratory Diagnosis, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia., Alnasser SM; Department of Pharmacology and Toxicology, Unaizah College of Pharmacy, Qassim University, Saudi Arabia., Al-Qubaisi MS; Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia., Ibrahim WN; Department of Biomedical Science, College of Health Sciences, QU Health, Qatar University, Doha, Qatar. |
المصدر: | Heliyon [Heliyon] 2023 Apr 17; Vol. 9 (5), pp. e15560. Date of Electronic Publication: 2023 Apr 17 (Print Publication: 2023). |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101672560 Publication Model: eCollection Cited Medium: Print ISSN: 2405-8440 (Print) Linking ISSN: 24058440 NLM ISO Abbreviation: Heliyon Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: London : Elsevier Ltd, [2015]- |
مستخلص: | Silver-doped magnesia nanoparticles (Ag/MgO) were synthesized using the precipitation method and characterized by various techniques such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), thermal gravimetric analysis (TGA), Brunner-Emmett-Teller (BET) surface area measurements, and dispersive X-ray spectroscopy (EDX). The morphology of Ag/MgO nanoparticles was determined by transmission and scanning electron microscopy, which revealed cuboidal shaped nanoparticles with sizes ranging from 31 to 68 nm and an average size of 43.5 ± 10.6 nm. The anticancer effects of Ag/MgO nanoparticles were evaluated on human colorectal (HT29) and lung adenocarcinoma (A549) cell lines, and their caspase-3, -8, and -9 activities, as well as Bcl-2, Bax, p53, cytochrome C protein expressions were estimated. Ag/MgO nanoparticles showed selective toxicity towards HT29 and A549 cells while remaining relatively innocuous towards the normal human colorectal, CCD-18Co, and lung, MRC-5 cells. The IC Competing Interests: The authors declare no conflict of interest.The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2023 The Authors.) |
References: | Int J Mol Sci. 2018 Aug 02;19(8):. (PMID: 30072642) J Drug Deliv. 2012;2012:751075. (PMID: 22007307) Toxicol In Vitro. 2014 Oct;28(7):1280-9. (PMID: 24997297) Int J Mol Sci. 2021 Jul 04;22(13):. (PMID: 34281254) Angew Chem Int Ed Engl. 2004 Feb 1;43(5):597-601. (PMID: 14743414) J Am Chem Soc. 2006 Feb 15;128(6):2115-20. (PMID: 16464114) Arch Toxicol. 2011 Jul;85(7):743-50. (PMID: 20428844) Drug Discov Today. 2015 May;20(5):595-601. (PMID: 25543008) Mater Sci Eng C Mater Biol Appl. 2019 Oct;103:109739. (PMID: 31349426) Int J Mol Sci. 2016 Sep 13;17(9):. (PMID: 27649147) J Proteomics. 2012 Jun 6;75(10):2811-23. (PMID: 22119545) Trends Cell Biol. 2023 Jan;33(1):18-29. (PMID: 35778326) Nat Prod Res. 2019 Dec;33(23):3454-3458. (PMID: 29842791) Int J Nanomedicine. 2013;8:2497-508. (PMID: 23885175) J Am Chem Soc. 2011 Nov 9;133(44):17594-7. (PMID: 21981727) J Nanobiotechnology. 2015 Oct 22;13:72. (PMID: 26493216) Water Res. 2008 Jun;42(12):3066-74. (PMID: 18359055) J Colloid Interface Sci. 2004 Jul 15;275(2):496-502. (PMID: 15178278) Toxicol Lett. 2011 Feb 25;201(1):92-100. (PMID: 21182908) J Appl Toxicol. 2021 May;41(5):683-700. (PMID: 33244813) Nanomedicine (Lond). 2007 Oct;2(5):681-93. (PMID: 17976030) Mater Sci Eng C Mater Biol Appl. 2020 May;110:110709. (PMID: 32204021) 3 Biotech. 2018 Mar;8(3):177. (PMID: 29556431) Int J Nanomedicine. 2010 Oct 05;5:753-62. (PMID: 21042421) Nat Prod Res. 2013;27(23):2216-8. (PMID: 23767409) Cells. 2018 Jan 10;7(1):. (PMID: 29320405) Chemosphere. 2019 Aug;229:169-180. (PMID: 31078031) Int J Nanomedicine. 2020 Oct 30;15:8479-8493. (PMID: 33154638) Nano Lett. 2013 Mar 13;13(3):1226-9. (PMID: 23387414) Nano Lett. 2005 May;5(5):829-34. (PMID: 15884879) Asian Pac J Cancer Prev. 2021 Mar 01;22(3):879-885. (PMID: 33773553) Signal Transduct Target Ther. 2022 Nov 19;7(1):379. (PMID: 36402753) Nanomedicine (Lond). 2020 Mar;15(6):547-561. (PMID: 32063101) Nanomaterials (Basel). 2022 Sep 09;12(18):. (PMID: 36144915) Nanomedicine (Lond). 2013 Aug;8(8):1307-22. (PMID: 23514434) J Nanosci Nanotechnol. 2005 Oct;5(10):1665-71. (PMID: 16245525) Int J Nanomedicine. 2020 Mar 09;15:1537-1548. (PMID: 32210550) Science. 2002 Dec 13;298(5601):2176-9. (PMID: 12481134) Biomed Pharmacother. 2021 Jun;138:111483. (PMID: 33744756) Molecules. 2011 Apr 06;16(4):2944-59. (PMID: 21471934) Int J Mol Sci. 2020 Mar 30;21(7):. (PMID: 32235542) Int J Nanomedicine. 2013;8:4115-29. (PMID: 24204141) J Colloid Interface Sci. 2005 Sep 15;289(2):402-9. (PMID: 16112224) Biotechnol Prog. 2006 Mar-Apr;22(2):577-83. (PMID: 16599579) Nanotechnol Sci Appl. 2008 Sep 19;1:17-32. (PMID: 24198458) Cancer Lett. 2011 Dec 8;311(2):131-40. (PMID: 21840122) ACS Appl Mater Interfaces. 2019 Feb 13;11(6):6589-6604. (PMID: 30653288) Nat Biotechnol. 2005 Jun;23(6):741-5. (PMID: 15908940) J Colloid Interface Sci. 2004 Jun 1;274(1):89-94. (PMID: 15120281) Oxid Med Cell Longev. 2018 Dec 12;2018:6121328. (PMID: 30647812) Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13549-54. (PMID: 14597719) |
فهرسة مساهمة: | Keywords: A549 cell; Ag/MgO nanoparticles; Antiproliferative; Apoptosis; HT29 cell |
تواريخ الأحداث: | Date Created: 20230509 Latest Revision: 20230511 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC10163622 |
DOI: | 10.1016/j.heliyon.2023.e15560 |
PMID: | 37159701 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2405-8440 |
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DOI: | 10.1016/j.heliyon.2023.e15560 |