دورية أكاديمية
أعرض في EDS

A Scoping Review of Kidney Transplantation in Africa: How Far have We Come?

التفاصيل البيبلوغرافية
العنوان: A Scoping Review of Kidney Transplantation in Africa: How Far have We Come?
المؤلفون: Davis SO; Urology, Surgery Interest Group of Africa, Lagos, Nigeria. davissamuelola@gmail.com., Zubair A; Urology, Surgery Interest Group of Africa, Lagos, Nigeria., Igbokwe M; Urology, Surgery Interest Group of Africa, Lagos, Nigeria., Abu M; Urology, Surgery Interest Group of Africa, Lagos, Nigeria., Chiedozie CA; Urology, Surgery Interest Group of Africa, Lagos, Nigeria., Sanni Q; Urology, Surgery Interest Group of Africa, Lagos, Nigeria., Jesuyajolu D; Urology, Surgery Interest Group of Africa, Lagos, Nigeria.
المصدر: World journal of surgery [World J Surg] 2023 Sep; Vol. 47 (9), pp. 2113-2123. Date of Electronic Publication: 2023 May 09.
نوع المنشور: Systematic Review; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 7704052 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2323 (Electronic) Linking ISSN: 03642313 NLM ISO Abbreviation: World J Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: 2024- : [Hoboken, NJ] : Wiley
Original Publication: New York, Springer International.
مواضيع طبية MeSH: Kidney Transplantation*/adverse effects , Kidney Failure, Chronic*/surgery, Humans ; Living Donors ; Nephrectomy ; Graft Rejection ; Africa ; Graft Survival
مستخلص: Introduction: Kidney transplantation is a life-saving treatment for end-stage kidney disease (ESKD) patients. However, access to this treatment in Africa lags behind other regions, leading to significant disparities in care. We aimed to analyse the indications, demographics, and outcomes of kidney transplantation in Africa.
Method: We conducted a systematic review of studies from PubMed, Google Scholar, and African Journal Online using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We pooled and analysed data on procedure type, graft outcomes, donor type, prophylaxis, post-operative complications, and survival from 33 eligible studies.
Result: The most common causes of ESKD requiring transplantation were glomerulonephritis and nephroangiosclerosis. Open nephrectomy was the predominant surgical approach (95%). Living donors accounted for 56.3% (4221) of all donors, with 68.5% being related to the recipient. Cadaveric donors accounted for 43.7% (3280) of transplants. Graft rejection was the most common surgical complication (39.44%), and 60.49% of patients developed hypertension in the follow-up period.
Conclusion: Our study highlights the potential of kidney transplantation to improve the lives of ESKD patients in Africa. However, further research and infrastructure development are necessary to make this treatment more widespread and successful.
(© 2023. Crown.)
التعليقات: Comment in: World J Surg. 2023 Sep;47(9):2124. (PMID: 37365322)
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تواريخ الأحداث: Date Created: 20230509 Date Completed: 20230801 Latest Revision: 20230809
رمز التحديث: 20230810
DOI: 10.1007/s00268-023-07042-0
PMID: 37160654
قاعدة البيانات: MEDLINE
الوصف
تدمد:1432-2323
DOI:10.1007/s00268-023-07042-0