دورية أكاديمية
Radiotherapy-associated sensorineural hearing loss in pediatric oncology patients.
| العنوان: | Radiotherapy-associated sensorineural hearing loss in pediatric oncology patients. |
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| المؤلفون: | Aslam MA; Department of Emergency Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan., Ahmad H; Department of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan., Malik HS; Department of Medicine, Rawalpindi Medical University, Rawalpindi, Pakistan., Uinarni H; Department of Anatomy, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia.; Radiologist at Pantai Indah Kapuk Hospital, Jakarta, Indonesia.; Radiologist at Pantai Indah Kapuk Hospital, Jakarta, Indonesia., Karim YS; Al-Manara College for Medical Sciences, Maysan, Iraq.; Al-Nisour University College, Baghdad, Iraq., Akhmedov YM; Department of Pediatric Surgery, Samarkand State Medical Institute, Samarkand, Uzbekistan.; Department of Scientific Affairs, Tashkent State Dental Institute, Makhtumkuli Street 103, Tashkent, 100047, Uzbekistan., Abdelbasset WK; Department of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia.; Department of Physical Therapy, Kasr Al-Aini Hospital, Cairo University, Giza, Egypt., Awadh SA; Department of Anesthesia, Al-Mustaqbal University, Babylon, Iraq., Abid MK; Department of Anesthesia, College of Health & medical Technology, Al-Ayen University, Thi-Qar, Iraq., Mustafa YF; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Mosul, Mosul-41001, Iraq., Farhood B; Department of Medical Physics and Radiology, Faculty of Paramedical Sciences, Kashan University of Medical Sciences, Kashan, Iran., Sahebkar A; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. |
| المصدر: | Current medicinal chemistry [Curr Med Chem] 2023 May 15. Date of Electronic Publication: 2023 May 15. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9440157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-533X (Electronic) Linking ISSN: 09298673 NLM ISO Abbreviation: Curr Med Chem Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Saif Zone, Sharjah, U.A.E. : Bentham Science Publishers Original Publication: Schiphol, The Netherlands : Bentham Science Publishers, |
| مستخلص: | During the radiotherapeutic treatment of pediatric oncology patients, they would be at a latent risk of developing ionizing radiation-induced ototoxicity when the cochlea or auditory nerve is located within the radiation field. Sensorineural hearing loss (SNHL) is an irreversible late complication of radiotherapy, and its incidence depends on various factors such as the patient's hearing sensitivity, total radiation dose to the cochlea, radiotherapy fractionation regimen, age and chemoradiation. Importantly, this complication exhibits serious challenges to adult survivors of childhood cancer, as it has been linked to impairments in academic achievement, psychosocial development, independent living skills, and employment in the survivor population. Therefore, early detection and proper management can alleviate academic, speech, language, social, and psychological morbidity arising from hearing deficits. In the present review, we have addressed issues such as underlying mechanisms of radiation-induced SNHL, audiometric findings of pediatric cancer patients treated with radiotherapy, and management and protection measures against radiation-induced ototoxicity. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.) |
| فهرسة مساهمة: | Keywords: Ototoxicity; Pediatric cancer; Radiotherapy; Sensorineural hearing loss; chemoradiation; childhood cancer |
| تواريخ الأحداث: | Date Created: 20230516 Latest Revision: 20230516 |
| رمز التحديث: | 20231215 |
| DOI: | 10.2174/0929867330666230515112245 |
| PMID: | 37190814 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1875-533X |
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| DOI: | 10.2174/0929867330666230515112245 |