دورية أكاديمية

Immunopathogenesis of corneal graft rejection.

التفاصيل البيبلوغرافية
العنوان: Immunopathogenesis of corneal graft rejection.
المؤلفون: Maharana PK; Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India., Mandal S; Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India., Kaweri L; Consultant, Department of Ophthalmology, Narayan Nethralaya, Bengaluru, Karnataka, India., Sahay P; Department of Ophthalmology, Centre for Sight Eye Hospital, New Delhi, India., Lata S; Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India., Asif MI; Department of Ophthalmology, Eye7 Chaudhary Eye Centre, New Delhi, India., Nagpal R; Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India., Sharma N; Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
المصدر: Indian journal of ophthalmology [Indian J Ophthalmol] 2023 May; Vol. 71 (5), pp. 1733-1738.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Medknow Publications Country of Publication: India NLM ID: 0405376 Publication Model: Print Cited Medium: Internet ISSN: 1998-3689 (Electronic) Linking ISSN: 03014738 NLM ISO Abbreviation: Indian J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: Mumbai : Medknow Publications
Original Publication: Bombay : All-India Ophthalmological Society
مواضيع طبية MeSH: Corneal Transplantation*/adverse effects , Corneal Diseases*/surgery, Humans ; Graft Rejection ; Cornea/pathology ; Anterior Chamber ; Postoperative Complications/pathology ; Keratoplasty, Penetrating/adverse effects
مستخلص: The most common cause of corneal graft failure is corneal graft rejection (CGR). Although cornea is one of the immune-privileged sites, it can still get a rejection episode due to a breach in its natural protective mechanism. Both anatomical and structural properties of cornea and anterior chamber contribute toward its immune tolerance. Clinically, every layer of the transplanted cornea can get a rejection episode. A proper understanding of immunopathogenesis will help in understanding the various mechanism of CGR and the development of newer strategies for the prevention and management of such cases.
Competing Interests: None
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فهرسة مساهمة: Keywords: Corneal graft rejection; endothelial rejection; graft failure; immune privilege; keratoplasty
تواريخ الأحداث: Date Created: 20230519 Date Completed: 20230522 Latest Revision: 20230803
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10391393
DOI: 10.4103/IJO.IJO_2866_22
PMID: 37203024
قاعدة البيانات: MEDLINE
الوصف
تدمد:1998-3689
DOI:10.4103/IJO.IJO_2866_22