دورية أكاديمية
Endovascular therapy outcome in isolated posterior cerebral artery occlusion strokes: A multicenter analysis of the Swiss Stroke Registry.
| العنوان: | Endovascular therapy outcome in isolated posterior cerebral artery occlusion strokes: A multicenter analysis of the Swiss Stroke Registry. |
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| المؤلفون: | Maulucci F; Stroke Centre, Neurology Department, Neurocentre of Southern Switzerland, EOC, Lugano, Switzerland., Disanto G; Stroke Centre, Neurology Department, Neurocentre of Southern Switzerland, EOC, Lugano, Switzerland., Bianco G; Stroke Centre, Neurology Department, Neurocentre of Southern Switzerland, EOC, Lugano, Switzerland., Pileggi M; Stroke Centre, Interventional and Diagnostic Neuroradiology, Neurocentre of Southern Switzerland, EOC, Lugano, Switzerland., Fischer U; Department of Neurology, University Hospital Bern, Bern, Switzerland.; Department of Neurology and Stroke Centre, University Hospital Basel, Basel, Switzerland., Padlina G; Department of Neurology, University Hospital Bern, Bern, Switzerland., Strambo D; Lausanne University Hospital, Stroke Centre, Neurology Service, Lausanne, Switzerland., Michel P; Lausanne University Hospital, Stroke Centre, Neurology Service, Lausanne, Switzerland., Kahles T; Department of Neurology, Kantonsspital Aarau, Aarau, Switzerland., Nedeltchev K; Department of Neurology, Kantonsspital Aarau, Aarau, Switzerland., Fisch U; Department of Neurology and Stroke Centre, University Hospital Basel, Basel, Switzerland., Bonati L; Department of Neurology and Stroke Centre, University Hospital Basel, Basel, Switzerland., Kägi G; Department of Neurology, Kantonsspital St. Gallen, St. Gallen, Switzerland., Escribano Paredes JB; Department of Neurology, Hôpitaux Universitaires de Genève, Geneva, Switzerland., Carrera E; Department of Neurology, Hôpitaux Universitaires de Genève, Geneva, Switzerland., Nyffeler T; Luzerner Kantonsspital, Centre of Neurology and Neurorehabilitation, Luzern, Switzerland., Bolognese M; Luzerner Kantonsspital, Centre of Neurology and Neurorehabilitation, Luzern, Switzerland., Wegener S; Universitätsspital Zürich, Neurology, Zürich, Switzerland., Luft A; Universitätsspital Zürich, Neurology, Zürich, Switzerland., Schelosky L; Kantonsspital Münsterlingen, Division of Neurology, Münsterlingen, Switzerland., Medlin F; Stroke Unit, Division of Neurology, HFR Fribourg, Fribourg, Switzerland., von Reding A; Neurology, Kantonsspital Winterthur, Winterthur, Switzerland., Peters N; Stroke Centre, Klinik Hirslanden, Zurich, Switzerland., Renaud S; Division of Neurology, Pourtalès Hospital, Neuchatel, Switzerland., Mono ML; Stadtspital Waid und Triemli, Stroke Unit, Zürich, Switzerland., Remonda L; Department of Interventional Neuroradiology, Kantonsspital Aarau, Aarau, Switzerland., Machi P; Department of Interventional Neuroradiology, Hôpitaux Universitaires de Genève, Geneva, Switzerland., Psychogios MN; Department of Interventional Neuroradiology, University Hospital Basel, Basel, Switzerland., Kaesmacher J; University Hospital Bern, Inselspital, Interventional Neuroradiology, Bern, Switzerland., Mordasini P; University Hospital Bern, Inselspital, Interventional Neuroradiology, Bern, Switzerland., Cereda CW; Stroke Centre, Neurology Department, Neurocentre of Southern Switzerland, EOC, Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland. |
| المصدر: | European stroke journal [Eur Stroke J] 2023 Jun; Vol. 8 (2), pp. 575-580. Date of Electronic Publication: 2023 Jan 13. |
| نوع المنشور: | Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publications Ltd Country of Publication: England NLM ID: 101688446 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2396-9881 (Electronic) Linking ISSN: 23969873 NLM ISO Abbreviation: Eur Stroke J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : SAGE Publications Ltd, [2016]- |
| مواضيع طبية MeSH: | Brain Ischemia* , Ischemic Stroke*/etiology , Stroke*/therapy , Endovascular Procedures*/adverse effects, Humans ; Thrombolytic Therapy/adverse effects ; Retrospective Studies ; Posterior Cerebral Artery ; Switzerland/epidemiology ; Treatment Outcome ; Intracranial Hemorrhages/etiology ; Registries |
| مستخلص: | Purpose: There is little data on the safety and efficacy of endovascular treatment (EVT) in comparison with intravenous thrombolysis (IVT) in acute ischemic stroke due to isolated posterior cerebral artery occlusion (IPCAO). We aimed to investigate the functional and safety outcomes of stroke patients with acute IPCAO treated with EVT (with or without prior bridging IVT) compared to IVT alone. Methods: We did a multicenter retrospective analysis of data from the Swiss Stroke Registry. The primary endpoint was overall functional outcome at 3 months in patients undergoing EVT alone or as part of bridging, compared with IVT alone (shift analysis). Safety endpoints were mortality and symptomatic intracranial hemorrhage. EVT and IVT patients were matched 1:1 using propensity scores. Differences in outcomes were examined using ordinal and logistic regression models. Findings: Out of 17,968 patients, 268 met the inclusion criteria and 136 were matched by propensity scores. The overall functional outcome at 3 months was comparable between the two groups (EVT vs IVT as reference category: OR = 1.42 for higher mRS, 95% CI = 0.78-2.57, p = 0.254). The proportion of patients independent at 3 months was 63.2% in EVT and 72.1% in IVT (OR = 0.67, 95% CI = 0.32-1.37, p = 0.272). Symptomatic intracranial hemorrhages were overall rare and present only in the IVT group (IVT = 5.9% vs EVT = 0%). Mortality at 3 months was also similar between the two groups (IVT = 0% vs EVT = 1.5%). Conclusion: In this multicenter nested analysis, EVT and IVT in patients with acute ischemic stroke due to IPCAO were associated with similar overall good functional outcome and safety. Randomized studies are warranted. |
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| فهرسة مساهمة: | Keywords: Acute ischemic stroke; posterior cerebral artery; thrombectomy |
| تواريخ الأحداث: | Date Created: 20230526 Date Completed: 20230529 Latest Revision: 20230713 |
| رمز التحديث: | 20230713 |
| مُعرف محوري في PubMed: | PMC10334166 |
| DOI: | 10.1177/23969873221150125 |
| PMID: | 37231695 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2396-9881 |
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| DOI: | 10.1177/23969873221150125 |