دورية أكاديمية
أعرض في EDS

Gut-Faecal Microbial and Health-Marker Response to Dietary Fumonisins in Weaned Pigs.

التفاصيل البيبلوغرافية
العنوان: Gut-Faecal Microbial and Health-Marker Response to Dietary Fumonisins in Weaned Pigs.
المؤلفون: Zeebone YY; Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Physiology and Nutrition, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary.; ELKH-MATE Mycotoxins in the Food Chain Research Group, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary., Bóta B; ELKH-MATE Mycotoxins in the Food Chain Research Group, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary., Halas V; Department of Farm Animal Nutrition, Institute of Animal Physiology and Nutrition, Kaposvár Campus, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary., Libisch B; Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi. Str., H-2100 Gödöllő, Hungary., Olasz F; Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi. Str., H-2100 Gödöllő, Hungary., Papp P; Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi. Str., H-2100 Gödöllő, Hungary., Keresztény T; Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi. Str., H-2100 Gödöllő, Hungary.; Doctoral School of Biology, Hungarian University of Agriculture and Life Sciences, H-2100 Gödöllő, Hungary., Gerőcs A; Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, Szent-Györgyi. Str., H-2100 Gödöllő, Hungary.; Doctoral School of Biology, ELTE Eötvös Loránd University, H-1117 Budapest, Hungary., Ali O; Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Physiology and Nutrition, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary.; ELKH-MATE Mycotoxins in the Food Chain Research Group, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary., Kovács M; Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Physiology and Nutrition, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary.; ELKH-MATE Mycotoxins in the Food Chain Research Group, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary., Szabó A; Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Physiology and Nutrition, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary.; ELKH-MATE Mycotoxins in the Food Chain Research Group, Hungarian University of Agriculture and Life Sciences, Guba S. Str., H-7400 Kaposvár, Hungary.
المصدر: Toxins [Toxins (Basel)] 2023 May 11; Vol. 15 (5). Date of Electronic Publication: 2023 May 11.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651 (Electronic) Linking ISSN: 20726651 NLM ISO Abbreviation: Toxins (Basel) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel : MDPI
مواضيع طبية MeSH: Fumonisins*/analysis , Microbiota*, Swine ; Animals ; Male ; RNA, Ribosomal, 16S/genetics ; Diet/veterinary ; Feces/microbiology ; Animal Feed/analysis
مستخلص: This study investigated effects of dietary fumonisins (FBs) on gut and faecal microbiota of weaned pigs. In total, 18 7-week-old male pigs were fed either 0, 15 or 30 mg FBs (FB 1 + FB 2 + FB 3 )/kg diet for 21 days. The microbiota was analysed with amplicon sequencing of the 16S rRNA gene V3-V4 regions (Illumina MiSeq). Results showed no treatment effect ( p > 0.05) on growth performance, serum reduced glutathione, glutathione peroxidase and malondialdehyde. FBs increased serum aspartate transaminase, gamma glutamyl-transferase and alkaline phosphatase activities. A 30 mg/kg FBs treatment shifted microbial population in the duodenum and ileum to lower levels (compared to control ( p < 0.05)) of the families Campylobacteraceae and Clostridiaceae , respectively, as well as the genera Alloprevotella , Campylobacter and Lachnospiraceae Incertae Sedis (duodenum), Turicibacter (jejunum), and Clostridium sensu stricto 1 (ileum). Faecal microbiota had higher levels of the Erysipelotrichaceae and Ruminococcaceae families and Solobacterium , Faecalibacterium , Anaerofilum , Ruminococcus , Subdoligranulum , Pseudobutyrivibrio , Coprococcus and Roseburia genera in the 30 mg/kg FBs compared to control and/or to the 15 mg/kg FBs diets. Lactobacillus was more abundant in the duodenum compared to faeces in all treatment groups ( p < 0.01). Overall, the 30 mg/kg FBs diet altered the pig gut microbiota without suppressing animal growth performance.
References: Appl Microbiol Biotechnol. 2019 Sep;103(17):7129-7140. (PMID: 31230101)
Animals (Basel). 2021 Apr 29;11(5):. (PMID: 33946901)
EFSA J. 2018 May 25;16(5):e05242. (PMID: 32625894)
Microbiologyopen. 2019 May;8(5):e00712. (PMID: 30117299)
Chem Biol Interact. 2010 May 14;185(3):157-62. (PMID: 20338158)
Appl Microbiol Biotechnol. 2015 May;99(10):4119-29. (PMID: 25808518)
Plant Pathol J. 2015 Sep;31(3):203-11. (PMID: 26361468)
Toxins (Basel). 2022 Feb 23;14(3):. (PMID: 35324660)
Nucleic Acids Res. 2013 Jan 7;41(1):e1. (PMID: 22933715)
Vet Microbiol. 2011 Nov 21;153(1-2):124-33. (PMID: 21658864)
Food Chem Toxicol. 2016 Nov;97:40-46. (PMID: 27575882)
Mol Nutr Food Res. 2007 Aug;51(8):925-31. (PMID: 17642075)
Animals (Basel). 2021 Aug 17;11(8):. (PMID: 34438875)
J Anim Physiol Anim Nutr (Berl). 2023 Mar;107(2):504-517. (PMID: 35534935)
PLoS One. 2017 Oct 26;12(10):e0185056. (PMID: 29073143)
Mol Nutr Food Res. 2017 Apr;61(4):. (PMID: 27921366)
J Nutr. 1978 Feb;108(2):211-5. (PMID: 621577)
Appl Environ Microbiol. 2009 Dec;75(23):7537-41. (PMID: 19801464)
Nat Toxins. 1993;1(4):222-8. (PMID: 8167938)
Microbiome. 2017 Mar 3;5(1):27. (PMID: 28253908)
Pol J Microbiol. 2017 Jul 06;66(2):245-250. (PMID: 28735320)
Microbiome. 2019 Jun 13;7(1):91. (PMID: 31196177)
Int J Food Microbiol. 2015 Aug 17;207:87-102. (PMID: 26001523)
Mediators Inflamm. 2016;2016:2839232. (PMID: 27610003)
Food Addit Contam. 2006 May;23(5):492-501. (PMID: 16644597)
Nature. 2010 Mar 4;464(7285):59-65. (PMID: 20203603)
Toxins (Basel). 2013 Apr 23;5(4):841-64. (PMID: 23612754)
J Vet Diagn Invest. 1993 Apr;5(2):232-41. (PMID: 8507702)
PLoS One. 2017 Jan 10;12(1):e0169851. (PMID: 28072880)
Toxicol Sci. 2016 Mar;150(1):54-63. (PMID: 26612839)
Toxins (Basel). 2019 Oct 31;11(11):. (PMID: 31683617)
Biomed Res Int. 2018 Oct 8;2018:3623274. (PMID: 30402473)
Acta Vet Hung. 2018 Sep;66(3):394-407. (PMID: 30264617)
Int J Mol Sci. 2019 Jun 06;20(11):. (PMID: 31174254)
J Anim Sci. 2020 Jan 1;98(1):. (PMID: 31758795)
Front Microbiol. 2017 Sep 04;8:1688. (PMID: 28928724)
Toxins (Basel). 2015 Apr 13;7(4):1253-72. (PMID: 25871822)
Appl Environ Microbiol. 1988 Jul;54(7):1806-11. (PMID: 2901247)
Appl Environ Microbiol. 2003 Oct;69(10):5870-4. (PMID: 14532038)
J Anim Sci. 2003 Nov;81(11):2792-803. (PMID: 14601883)
Microorganisms. 2019 Sep 12;7(9):. (PMID: 31547478)
Res Microbiol. 2006 Oct;157(8):792-801. (PMID: 16844349)
Genes Dis. 2017 Sep;4(3):138-148. (PMID: 30197908)
Mycotoxin Res. 2006 Dec;22(4):211-6. (PMID: 23605711)
Environ Health Perspect. 2001 May;109 Suppl 2:251-7. (PMID: 11359693)
Anal Biochem. 1968 Oct 24;25(1):192-205. (PMID: 4973948)
Toxins (Basel). 2019 Sep 19;11(9):. (PMID: 31546931)
Toxins (Basel). 2017 Jan 05;9(1):. (PMID: 28067768)
J Nutr. 2009 Jul;139(7):1303-7. (PMID: 19474154)
Front Microbiol. 2019 Jan 18;9:3335. (PMID: 30713531)
Toxins (Basel). 2021 Aug 31;13(9):. (PMID: 34564616)
Indian J Dermatol. 2016 May-Jun;61(3):251-60. (PMID: 27293244)
Microorganisms. 2020 Apr 15;8(4):. (PMID: 32326636)
Toxins (Basel). 2018 Jul 17;10(7):. (PMID: 30018261)
PLoS One. 2018 Aug 7;13(8):e0201901. (PMID: 30086169)
Toxins (Basel). 2018 Jun 05;10(6):. (PMID: 29874877)
ISME J. 2016 Dec;10(12):2973-2977. (PMID: 27177190)
J Vet Diagn Invest. 1990 Jul;2(3):217-21. (PMID: 2094448)
Toxins (Basel). 2022 Nov 18;14(11):. (PMID: 36422977)
Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1691-6. (PMID: 22307632)
Int J Syst Evol Microbiol. 2013 Apr;63(Pt 4):1214-1218. (PMID: 22753527)
Carcinogenesis. 1991 Jul;12(7):1247-51. (PMID: 1649015)
Nat Methods. 2010 May;7(5):335-6. (PMID: 20383131)
Proteomics. 2016 Mar;16(6):946-62. (PMID: 27001126)
فهرسة مساهمة: Keywords: Fusarium; faecal microbiota; fumonisin B; gut microbiota; health-markers; mycotoxin; weaned pigs
المشرفين على المادة: 0 (Fumonisins)
0 (RNA, Ribosomal, 16S)
تواريخ الأحداث: Date Created: 20230526 Date Completed: 20230529 Latest Revision: 20230530
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10222793
DOI: 10.3390/toxins15050328
PMID: 37235363
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6651
DOI:10.3390/toxins15050328