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Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence.

التفاصيل البيبلوغرافية
العنوان: Task state representations in vmPFC mediate relevant and irrelevant value signals and their behavioral influence.
المؤلفون: Moneta N; Max Planck Research Group NeuroCode, Max Planck Institute for Human Development, 14195, Berlin, Germany. moneta@mpib-berlin.mpg.de.; Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Berlin, 14195, Berlin, Germany. moneta@mpib-berlin.mpg.de.; Einstein Center for Neurosciences Berlin, Charité Universitätsmedizin Berlin, 10117, Berlin, Germany. moneta@mpib-berlin.mpg.de., Garvert MM; Max Planck Research Group NeuroCode, Max Planck Institute for Human Development, 14195, Berlin, Germany.; Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Berlin, 14195, Berlin, Germany.; Department of Psychology, Max Planck Institute for Human Cognitive and Brain Sciences, 04103, Leipzig, Germany., Heekeren HR; Einstein Center for Neurosciences Berlin, Charité Universitätsmedizin Berlin, 10117, Berlin, Germany.; Department of Education and Psychology, Freie Universität Berlin, 14195, Berlin, Germany.; Institute of Psychology, Universität Hamburg, 20146, Hamburg, Germany., Schuck NW; Max Planck Research Group NeuroCode, Max Planck Institute for Human Development, 14195, Berlin, Germany. schuck@mpib-berlin.mpg.de.; Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Berlin, 14195, Berlin, Germany. schuck@mpib-berlin.mpg.de.; Institute of Psychology, Universität Hamburg, 20146, Hamburg, Germany. schuck@mpib-berlin.mpg.de.
المصدر: Nature communications [Nat Commun] 2023 May 31; Vol. 14 (1), pp. 3156. Date of Electronic Publication: 2023 May 31.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : Nature Pub. Group
مواضيع طبية MeSH: Magnetic Resonance Imaging*/methods , Prefrontal Cortex*/diagnostic imaging, Humans ; Choice Behavior ; Reward ; Brain Mapping/methods
مستخلص: The ventromedial prefrontal-cortex (vmPFC) is known to contain expected value signals that inform our choices. But expected values even for the same stimulus can differ by task. In this study, we asked how the brain flexibly switches between such value representations in a task-dependent manner. Thirty-five participants alternated between tasks in which either stimulus color or motion predicted rewards. We show that multivariate vmPFC signals contain a rich representation that includes the current task state or context (motion/color), the associated expected value, and crucially, the irrelevant value of the alternative context. We also find that irrelevant value representations in vmPFC compete with relevant value signals, interact with task-state representations and relate to behavioral signs of value competition. Our results shed light on vmPFC's role in decision making, bridging between its role in mapping observations onto the task states of a mental map, and computing expected values for multiple states.
(© 2023. The Author(s).)
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تواريخ الأحداث: Date Created: 20230531 Date Completed: 20230602 Latest Revision: 20231101
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10232498
DOI: 10.1038/s41467-023-38709-w
PMID: 37258534
قاعدة البيانات: MEDLINE
الوصف
تدمد:2041-1723
DOI:10.1038/s41467-023-38709-w