دورية أكاديمية

Cascade Synthesis of 5-Aminotetrazoles from Isonitriles and N,N -Dibromoarylsulfonamides via Carbodiimide Coupling with Azide.

التفاصيل البيبلوغرافية
العنوان: Cascade Synthesis of 5-Aminotetrazoles from Isonitriles and N,N -Dibromoarylsulfonamides via Carbodiimide Coupling with Azide.
المؤلفون: Mishra D; Department of Chemistry, Gauhati University, Guwahati, Assam 781014, India., Kashyap S; Department of Chemistry, Gauhati University, Guwahati, Assam 781014, India., Phukan P; Department of Chemistry, Gauhati University, Guwahati, Assam 781014, India.
المصدر: The Journal of organic chemistry [J Org Chem] 2023 Jul 07; Vol. 88 (13), pp. 9401-9408. Date of Electronic Publication: 2023 Jun 05.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: PubMed not MEDLINE; MEDLINE
أسماء مطبوعة: Publication: Columbus Oh : American Chemical Society
Original Publication: Easton, Pa. [etc.]
مواضيع طبية MeSH: Azides* , Carbodiimides*, Tetrazoles
مستخلص: A cascade protocol for the synthesis of aminotetrazoles have been developed by treating isonitriles, N,N- dibromoarylsulfonamides, and sodium azides in the presence of K 2 CO 3 . This metal-free process proceeds via an isolable carbodiimide intermediate at room temperature, which could further react with sodium azide and subsequently cyclizes intermolecularly to provide 5-aminotetrazoles within a short reaction time. The present protocol's remarkable achievements are the wide substrate scope, good to excellent yields, and good functional group tolerance.
المشرفين على المادة: 0 (Azides)
4418-61-5 (5-amino-1H-tetrazole)
0 (Carbodiimides)
0 (Tetrazoles)
تواريخ الأحداث: Date Created: 20230605 Date Completed: 20230710 Latest Revision: 20230718
رمز التحديث: 20231215
DOI: 10.1021/acs.joc.3c00041
PMID: 37272415
قاعدة البيانات: MEDLINE
الوصف
تدمد:1520-6904
DOI:10.1021/acs.joc.3c00041