دورية أكاديمية
أعرض في EDS

Comparative Venom Multiomics Reveal the Molecular Mechanisms Driving Adaptation to Diverse Predator-Prey Ecosystems in Closely Related Sea Snakes.

التفاصيل البيبلوغرافية
العنوان: Comparative Venom Multiomics Reveal the Molecular Mechanisms Driving Adaptation to Diverse Predator-Prey Ecosystems in Closely Related Sea Snakes.
المؤلفون: Zheng H; Department of Critical Care Medicine, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.; School of Medicine, Shanghai University, Shanghai, China., Wang J; Department of Critical Care Medicine, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Fan H; Department of Critical Care Medicine, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Wang S; School of Medicine, Shanghai University, Shanghai, China., Ye R; School of Medicine, Shanghai University, Shanghai, China., Li L; School of Medicine, Shanghai University, Shanghai, China., Wang S; Department of Critical Care Medicine, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China., Li A; Department of Critical Care Medicine, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.; Department of Health Toxicology, Faculty of Naval Medicine, Naval Medical University, Shanghai, China., Lu Y; Department of Critical Care Medicine, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.; School of Medicine, Shanghai University, Shanghai, China.; Department of Biochemical Pharmacy, School of Pharmacy, Naval Medical University, Shanghai, China.
المصدر: Molecular biology and evolution [Mol Biol Evol] 2023 Jun 01; Vol. 40 (6).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 8501455 Publication Model: Print Cited Medium: Internet ISSN: 1537-1719 (Electronic) Linking ISSN: 07374038 NLM ISO Abbreviation: Mol Biol Evol Subsets: MEDLINE
أسماء مطبوعة: Publication: 2003- : New York, NY : Oxford University Press
Original Publication: [Chicago, Ill.] : University of Chicago Press, [c1983-
مواضيع طبية MeSH: Hydrophiidae*, Animals ; Phylogeny ; Ecosystem ; Proteomics ; Multiomics ; Elapid Venoms/chemistry ; Elapid Venoms/genetics
مستخلص: Predator-prey arms races are ideal models for studying the natural selection and adaptive evolution that drive the formation of biological diversity. For venomous snakes, venom is a key bridge linking snakes with their prey, but whether and how venom evolves under the selection of diet remains unclear. Here, we focused on two closely related sea snakes, Hydrophis cyanocinctus and Hydrophis curtus, which show significant differences in prey preferences. Data-independent acquisition (DIA)-based proteomic analysis revealed different degrees of homogeneity in the venom composition of the two snakes, which was consistent with the differential phylogenetic diversity of their prey. By investigating the sequences and structures of three-finger toxins (3FTx), a predominant toxin family in elapid venom, we identified significant differences between the two sea snakes in the binding activity of 3FTx to receptors from different prey populations, which could explain the trophic specialization of H. cyanocinctus. Furthermore, we performed integrated multiomic profiling of the transcriptomes, microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and proteomes of the venom glands; constructed venom-related mRNA-miRNA-lncRNA networks; and identified a series of noncoding RNAs involved in the regulation of toxin gene expression in the two species. These findings are highly informative for elucidating the molecular basis and regulatory mechanisms that account for discrepant venom evolution in response to divergent diets in closely related snakes, providing valuable evidence for the study of coselection and coevolution in predator-prey ecosystems.
(© The Author(s) 2023. Published by Oxford University Press on behalf of Society for Molecular Biology and Evolution.)
References: Bioinformatics. 2012 Aug 15;28(16):2184-5. (PMID: 22743226)
Science. 2017 Sep 22;357(6357):1261-1266. (PMID: 28935799)
Toxicon. 1999 Feb;37(2):249-52; author reply 253-60. (PMID: 10078860)
Toxicon. 2001 Jan;39(1):87-96. (PMID: 10936625)
Nucleic Acids Res. 2008 Jan;36(Database issue):D154-8. (PMID: 17991681)
Nature. 2021 Aug;596(7873):583-589. (PMID: 34265844)
Nat Biotechnol. 2019 Apr;37(4):420-423. (PMID: 30778233)
Toxins (Basel). 2021 Feb 09;13(2):. (PMID: 33572266)
Toxicon. 2020 Nov;187:35-46. (PMID: 32871160)
Nucleic Acids Res. 2013 Sep;41(17):e166. (PMID: 23892401)
Nat Commun. 2021 Nov 12;12(1):6566. (PMID: 34772935)
Mol Biol Evol. 2021 Oct 27;38(11):4867-4883. (PMID: 34320652)
Proc Natl Acad Sci U S A. 2021 Apr 27;118(17):. (PMID: 33875585)
Genome Biol. 2003;5(1):R1. (PMID: 14709173)
Nature. 2015 Feb 19;518(7539):371-5. (PMID: 25686609)
BMC Genomics. 2013 Apr 10;14:234. (PMID: 23575160)
Neuron. 2020 Jun 17;106(6):952-962.e5. (PMID: 32275860)
Proteomics. 2020 Sep;20(17-18):e1900276. (PMID: 32275110)
Gene. 2000 Dec 30;261(1):43-52. (PMID: 11164036)
Nat Commun. 2022 Aug 4;13(1):4543. (PMID: 35927270)
Nature. 2022 Sep;609(7928):747-753. (PMID: 36002568)
Nat Protoc. 2020 May;15(5):1829-1852. (PMID: 32269383)
Bioinformatics. 2012 Dec 15;28(24):3211-7. (PMID: 23071270)
Bioinformatics. 2001 Jul;17(7):646-53. (PMID: 11448883)
BMC Bioinformatics. 2014 Sep 19;15:311. (PMID: 25239089)
Nat Methods. 2022 Jun;19(6):679-682. (PMID: 35637307)
Bioinformatics. 2014 Aug 1;30(15):2114-20. (PMID: 24695404)
Nature. 1996 Feb 8;379(6565):537-40. (PMID: 8596631)
Biochimie. 2004 Feb;86(2):137-49. (PMID: 15016453)
Proc Biol Sci. 2009 Jul 7;276(1666):2443-9. (PMID: 19364745)
Nat Biotechnol. 2019 Aug;37(8):907-915. (PMID: 31375807)
Science. 2019 Jun 21;364(6446):. (PMID: 31221828)
Mol Biol Evol. 2022 Aug 06;:. (PMID: 35932227)
Cell. 2011 Oct 14;147(2):358-69. (PMID: 22000014)
Nature. 2020 Aug;584(7821):403-409. (PMID: 32760000)
R Soc Open Sci. 2018 Mar 28;5(3):172141. (PMID: 29657807)
Nat Biotechnol. 2015 Mar;33(3):290-5. (PMID: 25690850)
Nature. 2006 Aug 3;442(7102):515-6. (PMID: 16885968)
Physiol Rev. 2016 Oct;96(4):1297-325. (PMID: 27535639)
Nat Rev Genet. 2012 Mar 13;13(4):227-32. (PMID: 22411467)
Cell. 2018 Mar 22;173(1):20-51. (PMID: 29570994)
J Proteome Res. 2017 Sep 1;16(9):3370-3390. (PMID: 28731347)
Int J Mol Sci. 2016 Nov 22;17(11):. (PMID: 27879679)
F1000Res. 2019 Nov 7;8:1874. (PMID: 33552473)
Zool Res. 2018 Nov 18;39(6):431-436. (PMID: 30084433)
Mol Phylogenet Evol. 2013 Mar;66(3):575-91. (PMID: 23026811)
Nucleic Acids Res. 1998 Jan 1;26(1):320-2. (PMID: 9399864)
Cell. 2018 Jan 25;172(3):393-407. (PMID: 29373828)
Genome Biol. 2011;12(3):R22. (PMID: 21410973)
Genome Biol. 2016 Feb 02;17:19. (PMID: 26838501)
Nucleic Acids Res. 2017 Jul 3;45(W1):W12-W16. (PMID: 28521017)
Mol Ecol. 2013 May;22(10):2742-59. (PMID: 23506038)
BMC Biol. 2022 Jan 7;20(1):4. (PMID: 34996434)
Sci Rep. 2016 May 09;6:25672. (PMID: 27158082)
Toxicon. 2022 Sep;216:92-106. (PMID: 35820472)
Parasit Vectors. 2014 Apr 10;7:177. (PMID: 24721600)
Comp Biochem Physiol B Biochem Mol Biol. 2020 Oct - Nov;248-249:110482. (PMID: 32712271)
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4. (PMID: 16381832)
Toxins (Basel). 2018 Dec 23;11(1):. (PMID: 30583590)
Nat Methods. 2013 Jan;10(1):71-3. (PMID: 23160280)
Nat Rev Genet. 2015 Jul;16(7):421-33. (PMID: 26077373)
Toxicon. 2018 Oct;153:96-105. (PMID: 30189242)
Toxins (Basel). 2021 Aug 06;13(8):. (PMID: 34437419)
فهرسة مساهمة: Keywords: biodiversity; diet divergence; multiomics; ncRNAs; predator–prey
المشرفين على المادة: 0 (Elapid Venoms)
تواريخ الأحداث: Date Created: 20230606 Date Completed: 20230616 Latest Revision: 20230619
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10265070
DOI: 10.1093/molbev/msad125
PMID: 37279580
قاعدة البيانات: MEDLINE
الوصف
تدمد:1537-1719
DOI:10.1093/molbev/msad125