دورية أكاديمية
Mechanisms and treatment outcomes of ostial right coronary artery in-stent restenosis.
العنوان: | Mechanisms and treatment outcomes of ostial right coronary artery in-stent restenosis. |
---|---|
المؤلفون: | Yamamoto K; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Sato T; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Salem H; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA.; Cardiovascular Medicine Department, Faculty of Medicine - Tanta University, Tanta, Egypt., Matsumura M; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Fall KN; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA., Prasad M; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA., Ng VG; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA., Sethi SS; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA., Nazif TM; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Parikh SA; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Vahl TP; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Ali ZA; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA.; St. Francis Hospital, Roslyn, NY, USA., Karmpaliotis D; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA.; Gagnon Cardiovascular Institute, Morristown Medical Center, Morristown, NJ, USA., Rabbani LE; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Collins MB; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA., Leon MB; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., McEntegart MB; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Moses JW; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Kirtane AJ; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Mintz GS; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA., Maehara A; Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, NY, USA.; Clinical Trials Center, Cardiovascular Research Foundation, New York, NY, USA. |
المصدر: | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology [EuroIntervention] 2023 Aug 07; Vol. 19 (5), pp. e383-e393. Date of Electronic Publication: 2023 Aug 07. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Société Europa édition Country of Publication: France NLM ID: 101251040 Publication Model: Electronic Cited Medium: Internet ISSN: 1969-6213 (Electronic) Linking ISSN: 1774024X NLM ISO Abbreviation: EuroIntervention Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Toulouse : Société Europa édition, c2005- |
مواضيع طبية MeSH: | Coronary Restenosis*/diagnostic imaging , Coronary Restenosis*/etiology , Coronary Restenosis*/therapy, Humans ; Coronary Vessels/diagnostic imaging ; Coronary Vessels/surgery ; Coronary Angiography/adverse effects ; Treatment Outcome ; Stents/adverse effects |
مستخلص: | Background: Despite a high rate of in-stent restenosis (ISR) after stenting the right coronary artery (RCA) ostium, the mechanism of ostial RCA ISR is not well understood. Aims: We aimed to clarify the cause of ostial RCA ISR using intravascular ultrasound (IVUS). Methods: Overall, 139 ostial RCA ISR lesions were identified with IVUS, pre-revascularisation. Primary ISR mechanisms were classified as follows: 1) neointimal hyperplasia (NIH); 2) neoatherosclerosis; 3) ostium not covered by the stent; 4) stent fracture or deformation; 5) stent underexpansion (old minimum stent area <4.0 mm 2 or stent expansion <50%); or 6) a protruding calcified nodule. Results: The median duration from prior stenting was 1.2 (first quartile 0.6, third quartile 3.1) years. The primary mechanisms of ISR were NIH in 25% (n=35) of lesions, neoatherosclerosis in 22% (n=30), uncovered ostium in 6% (n=9) (biological cause 53%, n=74), stent fracture or deformation in 25% (n=35), underexpansion in 11% (n=15), and protruding calcified nodules in 11% (n=15) (mechanical cause 47%, n=65). Including secondary mechanisms, 51% (n=71) of ostial RCA ISRs had stent fractures that were associated with greater hinge motion of the ostial-aorta angle during the cardiac cycle. The Kaplan-Meier rate of target lesion failure at 1 year was 11.5%. When the mechanically caused ISRs were treated without new stents, they suffered a higher subsequent event rate (41.4%) compared with non-mechanical causes or mechanical causes treated without restenting (7.8%, unadjusted hazard ratio 6.44, 95% confidence interval: 2.33-17.78; p<0.0001). Conclusions: Half of the ostial RCA ISRs were due to mechanical causes. Subsequent event rates were high, especially in mechanically caused ISRs treated without the implantation of a new stent. |
References: | Cardiovasc Ther. 2017 Apr;35(2):. (PMID: 28039928) J Am Heart Assoc. 2020 Oct 20;9(19):e016595. (PMID: 32964759) EuroIntervention. 2017 Jun 20;13(3):294-302. (PMID: 28320686) Am J Cardiol. 2013 May 15;111(10):1408-14. (PMID: 23433757) J Am Coll Cardiol. 2021 Apr 6;77(13):1599-1611. (PMID: 33795033) JACC Cardiovasc Interv. 2016 Jun 13;9(11):1115-23. (PMID: 27009464) Catheter Cardiovasc Interv. 2015 Mar;85(4):524-31. (PMID: 24753036) J Am Coll Cardiol. 2013 Jun 18;61(24):2406-2416. (PMID: 23602769) JACC Cardiovasc Interv. 2021 Aug 9;14(15):1639-1650. (PMID: 34353595) Cardiovasc Interv Ther. 2018 Oct;33(4):321-327. (PMID: 28929334) Am J Cardiol. 1997 May 15;79(10):1334-8. (PMID: 9165153) J Am Heart Assoc. 2016 Mar 15;5(3):e003255. (PMID: 26979080) Am J Cardiol. 1991 Feb 15;67(5):431-3. (PMID: 1994670) EuroIntervention. 2015 Jul;11(3):301-7. (PMID: 24694540) Atherosclerosis. 2021 Feb;318:70-75. (PMID: 33243488) J Interv Cardiol. 2015 Aug;28(4):365-73. (PMID: 26138831) Catheter Cardiovasc Interv. 2016 Feb 1;87(2):232-40. (PMID: 23728924) Anat Rec. 1965 Nov;153(3):233-41. (PMID: 5880315) JACC Cardiovasc Imaging. 2012 Feb;5(2):232-3. (PMID: 22340834) J Am Soc Echocardiogr. 2018 Feb;31(2):117-147. (PMID: 29254695) JACC Cardiovasc Interv. 2015 Oct;8(12):1586-94. (PMID: 26386758) Circ J. 2009 Nov;73(11):2036-41. (PMID: 19713648) EuroIntervention. 2014 Mar 20;9(11):1301-8. (PMID: 24650772) J Invasive Cardiol. 2011 Aug;23(8):322-6. (PMID: 21828393) J Am Coll Cardiol. 2009 Nov 17;54(21):1924-31. (PMID: 19909872) Coron Artery Dis. 2004 Feb;15(1):39-44. (PMID: 15201619) Int J Cardiol. 2022 Oct 15;365:106-111. (PMID: 35870637) Lancet. 2019 Jun 22;393(10190):2503-2510. (PMID: 31056295) J Am Coll Cardiol. 2010 May 4;55(18):1936-42. (PMID: 20430265) |
تواريخ الأحداث: | Date Created: 20230607 Date Completed: 20230808 Latest Revision: 20240808 |
رمز التحديث: | 20240808 |
مُعرف محوري في PubMed: | PMC10397676 |
DOI: | 10.4244/EIJ-D-23-00107 |
PMID: | 37283548 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1969-6213 |
---|---|
DOI: | 10.4244/EIJ-D-23-00107 |