دورية أكاديمية
Overtreatment and associated risk factors among multimorbid older patients with diabetes.
العنوان: | Overtreatment and associated risk factors among multimorbid older patients with diabetes. |
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المؤلفون: | Baretella O; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland., Alwan H; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Graduate School for Health Sciences, University of Bern, Bern, Switzerland., Feller M; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland., Aubert CE; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland., Del Giovane C; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland., Papazoglou D; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland., Christiaens A; Institut Pierre Louis d'Epidémiologie et de Santé Publique, Sorbonne Université, INSERM, Paris, France.; Clinical Pharmacy research group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium., Meinders AJ; Department of Internal Medicine, St Antonius Hospital, Nieuwegein, the Netherlands., Byrne S; School of Pharmacy, University College Cork - National University of Ireland, Cork, Republic of Ireland., Kearney PM; School of Public Health, University College Cork, Cork, Republic of Ireland.; Department of Medicine Cork, University College Cork - National University of Ireland, Cork, Republic of Ireland., O'Mahony D; Department of Medicine Cork, University College Cork - National University of Ireland, Cork, Republic of Ireland.; Department of Geriatric Medicine Cork, Cork University Hospital Group, Cork, Republic of Ireland., Knol W; Department of Geriatrics and Expertise Centre Pharmacotherapy in Old Persons (EPHOR), University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Boland B; Clinical Pharmacy research group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.; Department of Geriatric Medicine, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium., Gencer B; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Service de cardiologie, Hôpitaux Universitaires de Genève (HUG), Geneva, Switzerland., Aujesky D; Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland., Rodondi N; Institute of Primary Health Care (BIHAM), University of Bern, Bern, Switzerland.; Department of General Internal Medicine, Inselspital, Bern University Hospital, Bern, Switzerland. |
المصدر: | Journal of the American Geriatrics Society [J Am Geriatr Soc] 2023 Sep; Vol. 71 (9), pp. 2893-2901. Date of Electronic Publication: 2023 Jun 07. |
نوع المنشور: | Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Blackwell Science Country of Publication: United States NLM ID: 7503062 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-5415 (Electronic) Linking ISSN: 00028614 NLM ISO Abbreviation: J Am Geriatr Soc Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Malden, MA : Blackwell Science Original Publication: New York [etc.] |
مواضيع طبية MeSH: | Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/epidemiology , Metformin*/therapeutic use, Humans ; Female ; Aged ; Male ; Multimorbidity ; Risk Factors ; Polypharmacy ; Hypoglycemic Agents/therapeutic use |
مستخلص: | Background: In multimorbid older patients with type 2 diabetes mellitus (T2DM), the intensity of glucose-lowering medication (GLM) should be focused on attaining a suitable level of glycated hemoglobin (HbA Methods: In a secondary analysis of a multicenter study of multimorbid older patients, we evaluated HbA Results: Among the 564 patients with T2DM (median age 78 years, 39% women), mean ± standard deviation HbA Conclusions: In this multicountry study of multimorbid older patients with T2DM, more than one third were overtreated, highlighting the high prevalence of this problem. Careful balancing of benefits and risks in the choice of GLM may improve patient care, especially in the context of comorbidities such as severe renal impairment, and frequent non-GP healthcare contacts. (© 2023 The Authors. Journal of the American Geriatrics Society published by Wiley Periodicals LLC on behalf of The American Geriatrics Society.) |
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معلومات مُعتمدة: | 634238 International ERC_ European Research Council; SNSF 320030_188549 Switzerland SNSF_ Swiss National Science Foundation; SNSF 325130_204361/1 Switzerland SNSF_ Swiss National Science Foundation |
فهرسة مساهمة: | Keywords: HbA1c; glucose-lowering medication; multimorbidity; polypharmacy; type 2 diabetes mellitus |
المشرفين على المادة: | 9100L32L2N (Metformin) 0 (Hypoglycemic Agents) |
تواريخ الأحداث: | Date Created: 20230607 Date Completed: 20230915 Latest Revision: 20230918 |
رمز التحديث: | 20231215 |
DOI: | 10.1111/jgs.18465 |
PMID: | 37286338 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1532-5415 |
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DOI: | 10.1111/jgs.18465 |