دورية أكاديمية

Targeting long noncoding RNAs in neuroblastoma: Progress and prospects.

التفاصيل البيبلوغرافية
العنوان: Targeting long noncoding RNAs in neuroblastoma: Progress and prospects.
المؤلفون: Ataei A; School of Medicine, Bam University of Medical Sciences, Bam, Iran., Tahsili M; Payam Nour University of Taft, Yazd, Iran., Hayadokht G; School of Medicine, Guilan University of Medical Sciences, Rasht, Iran., Daneshvar M; Tehran University of Medical Sciences, Tehran, Iran., Mohammadi Nour S; School of Pharmacy, Ardabil University of Medical Sciences, Ardabil, Iran., Soofi A; Department of Physical Chemistry, School of Chemistry, College of Sciences, University of Tehran, Tehran, Iran., Masoudi A; Department of Laboratory Sciences, Faculty of Alied Medical Sciences, Qom University of Medical Sciences, Qom, Iran., Kabiri M; Faculty of Medicine, Islamic Azad University of Medical Sciences, Tehran, Iran., Natami M; Department of Urology, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
المصدر: Chemical biology & drug design [Chem Biol Drug Des] 2023 Sep; Vol. 102 (3), pp. 640-652. Date of Electronic Publication: 2023 Jun 08.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Oxford : Wiley-Blackwell, 2006-
مواضيع طبية MeSH: RNA, Long Noncoding*/genetics , Neuroblastoma*, Child ; Humans ; Child, Preschool ; Prognosis ; Gene Expression Regulation, Neoplastic ; Biomarkers, Tumor/genetics
مستخلص: Neuroblastoma (NB) is the third most prevalent tumor that mostly influences infants and young children. Although different treatments have been developed for the treatment of NB, high-risk patients have been reported to have low survival rates. Currently, long noncoding RNAs (lncRNAs) have shown an attractive potential in cancer research and a party of investigations have been performed to understand mechanisms underlying tumor development through lncRNA dysregulation. Researchers have just newly initiated to exhibit the involvement of lncRNAs in NB pathogenesis. In this review article, we tried to clarify the point we stand with respect to the involvement of lncRNAs in NB. Moreover, implications for the pathologic roles of lncRNAs in the development of NB have been discussed. It seems that some of these lncRNAs have promising potential to be applied as biomarkers for NB prognosis and treatment.
(© 2023 John Wiley & Sons Ltd.)
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فهرسة مساهمة: Keywords: biomarkers; lncRNA; neuroblastoma; prognosis
المشرفين على المادة: 0 (RNA, Long Noncoding)
0 (Biomarkers, Tumor)
تواريخ الأحداث: Date Created: 20230609 Date Completed: 20230814 Latest Revision: 20230820
رمز التحديث: 20230820
DOI: 10.1111/cbdd.14263
PMID: 37291742
قاعدة البيانات: MEDLINE
الوصف
تدمد:1747-0285
DOI:10.1111/cbdd.14263