دورية أكاديمية
Biotech Application of Exopolysaccharides from Curvularia brachyspora : Optimization of Production, Structural Characterization, and Biological Activity.
العنوان: | Biotech Application of Exopolysaccharides from Curvularia brachyspora : Optimization of Production, Structural Characterization, and Biological Activity. |
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المؤلفون: | Menolli RA; Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel 85819-110, PR, Brazil.; Faculdades Pequeno Príncipe, Curitiba 80230-020, PR, Brazil.; Instituto de Pesquisa Pelé Pequeno Príncipe, Curitiba 80240-020, PR, Brazil., Tessaro FHG; Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo 05508-000, SP, Brazil., do Amaral AE; Unidade de Laboratório de Análises Clínicas, Universidade Federal de Santa Catarina, Florianópolis 88036-800, SC, Brazil., de Melo RH; Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel 85819-110, PR, Brazil., Dos Santos JF; Faculdades Pequeno Príncipe, Curitiba 80230-020, PR, Brazil.; Instituto de Pesquisa Pelé Pequeno Príncipe, Curitiba 80240-020, PR, Brazil., Iacomini M; Department of Biochemistry and Molecular Biology, Federal University of Paraná, Curitiba 81531-980, PR, Brazil., Smiderle FR; Faculdades Pequeno Príncipe, Curitiba 80230-020, PR, Brazil.; Instituto de Pesquisa Pelé Pequeno Príncipe, Curitiba 80240-020, PR, Brazil., Mello RG; Faculdades Pequeno Príncipe, Curitiba 80230-020, PR, Brazil.; Instituto de Pesquisa Pelé Pequeno Príncipe, Curitiba 80240-020, PR, Brazil. |
المصدر: | Molecules (Basel, Switzerland) [Molecules] 2023 May 26; Vol. 28 (11). Date of Electronic Publication: 2023 May 26. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI, c1995- |
مواضيع طبية MeSH: | Polysaccharides*/pharmacology , Macrophages*, Animals ; Mice ; Spectroscopy, Fourier Transform Infrared ; Biotechnology |
مستخلص: | C. brachyspora , a widespread dematiaceous fungus, was evaluated in this study to optimize the production of exopolysaccharides (CB-EPS). Optimization was performed using response surface methodology, and the best production yielded 75.05% of total sugar at pH 7.4, with 0.1% urea, after 197 h. The obtained CB-EPS showed typical signals of polysaccharides, which was confirmed by FT-IR and NMR. The HPSEC analysis indicated a polydisperse polymer, showing a non-uniform peak, with an average molar mass (M |
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معلومات مُعتمدة: | 001 Fundação Araucária; CP 08/2009 - PP-SUS Ministry of Health |
فهرسة مساهمة: | Keywords: biological activity; dematiaceous fungi; fungal production; polysaccharide; response surface methodology |
المشرفين على المادة: | 0 (Polysaccharides) |
SCR Organism: | Curvularia brachyspora |
تواريخ الأحداث: | Date Created: 20230610 Date Completed: 20230612 Latest Revision: 20230612 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC10254318 |
DOI: | 10.3390/molecules28114356 |
PMID: | 37298832 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1420-3049 |
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DOI: | 10.3390/molecules28114356 |