دورية أكاديمية
Feasibility of physiological pacing rate in cardiac resynchronization therapy.
| العنوان: | Feasibility of physiological pacing rate in cardiac resynchronization therapy. |
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| المؤلفون: | Spaggiari CV; Department of Artificial Cardiac Pacemaker Stimulation and Cardiac Rehabilitation, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., de Siqueira SF; Department of Artificial Cardiac Pacemaker Stimulation and Cardiac Rehabilitation, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., de Oliveira CP; Department of Artificial Cardiac Pacemaker Stimulation and Cardiac Rehabilitation, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Guiarão Gomes CI; Department of Artificial Cardiac Pacemaker Stimulation and Cardiac Rehabilitation, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Alves MJNN; Department of Artificial Cardiac Pacemaker Stimulation and Cardiac Rehabilitation, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Filho MM; Department of Artificial Cardiac Pacemaker Stimulation and Cardiac Rehabilitation, Instituto do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. |
| المصدر: | ESC heart failure [ESC Heart Fail] 2023 Aug; Vol. 10 (4), pp. 2751-2753. Date of Electronic Publication: 2023 Jun 12. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley & Sons Ltd on behalf of the European Society of Cardiology Country of Publication: England NLM ID: 101669191 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2055-5822 (Electronic) Linking ISSN: 20555822 NLM ISO Abbreviation: ESC Heart Fail Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [Oxford] : John Wiley & Sons Ltd on behalf of the European Society of Cardiology, [2014]- |
| مواضيع طبية MeSH: | Cardiac Resynchronization Therapy* , Heart Failure*/therapy, Humans ; Feasibility Studies ; Treatment Outcome ; Walk Test |
| مستخلص: | Aims: Although cardiac resynchronization therapy (CRT) improves functional capacity in heart failure patients, a blunted heart rate (HR) response remains after treatment. So we aimed to evaluate the feasibility of the physiological pacing rate (PPR) in CRT patients. Methods: A cohort of 30 clinical mildly symptomatic CRT patients underwent the six-minute walk test (6MWT). During the 6MWT, HR, blood pressure, and maximum walking distance were assessed. The measurements were obtained in a pre to post manner, with CRT at nominal settings and with the physiological phase (CRT PPR), in which HR was increased by 10% above the maximum HR achieved previously. The CRT cohort also comprised a matched control group (CRT CG). In the CRT CG, the 6MWT was repeated after the standard evaluation with no PPR. The evaluations were blinded for patients and for the 6MWT evaluator. Results: During the 6MWT, CRT PPR led to an increase in walking distance of 40.5 m (9.2%; P < 0.0001) when compared with baseline trial. Additionally, CRT PPR increased the maximum walking distance compared with CRT CG 479.3 ± 68.9 m vs. 420.3 ± 44.8 m, respectively, P = 0.001. In the CRT CG, CRT PPR increased the variation in walking distance, compared with baseline trials, respectively 2.40 ± 3.8% vs. 9.25 ± 7.0%, P = 0.007. Conclusions: In mildly symptomatic CRT patients PPR is feasible, leading to improvements in functional capacity. In this regard, the efficacy of PPR must be confirmed by controlled randomized trials. (© 2023 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.) |
| References: | J Am Coll Cardiol. 2005 Dec 20;46(12):2292-7. (PMID: 16360061) Respir Care. 2003 Aug;48(8):783-5. (PMID: 12890299) ESC Heart Fail. 2023 Aug;10(4):2751-2753. (PMID: 37306670) Cardiopulm Phys Ther J. 2013 Sep;24(3):21-9. (PMID: 23997688) Eur J Heart Fail. 2008 Jan;10(1):96-101. (PMID: 18096432) J Cardiovasc Electrophysiol. 2019 Nov;30(11):2591-2598. (PMID: 31544272) |
| فهرسة مساهمة: | Keywords: Cardiac resynchronization therapy; Heart failure; Heart rate |
| تواريخ الأحداث: | Date Created: 20230612 Date Completed: 20230731 Latest Revision: 20230801 |
| رمز التحديث: | 20230801 |
| مُعرف محوري في PubMed: | PMC10375173 |
| DOI: | 10.1002/ehf2.14429 |
| PMID: | 37306670 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2055-5822 |
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| DOI: | 10.1002/ehf2.14429 |