دورية أكاديمية

[Translated article] The efficacy of topical tranexamic acid in reverse shoulder arthroplasty.

التفاصيل البيبلوغرافية
العنوان: [Translated article] The efficacy of topical tranexamic acid in reverse shoulder arthroplasty.
المؤلفون: Garcia-Maya B; Hospital Universitario Infanta Elena, Madrid, Spain. Electronic address: beatriz.garcia.maya@gmail.com., Morais S; Araba University Hospital Txagorritxu Campus, Araba, Spain., Diez-Sebastian J; Hospital La Paz Institute for Health Research, Madrid, Spain., Antuña S; La Paz University Hospital, Madrid, Spain., Barco R; La Paz University Hospital, Madrid, Spain.
المصدر: Revista espanola de cirugia ortopedica y traumatologia [Rev Esp Cir Ortop Traumatol] 2023 Sep-Oct; Vol. 67 (5), pp. T387-T393. Date of Electronic Publication: 2023 Jun 11.
نوع المنشور: Journal Article
اللغة: English; Spanish; Castilian
بيانات الدورية: Publisher: Elsevier Doyma Country of Publication: Spain NLM ID: 101477399 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1988-8856 (Electronic) Linking ISSN: 18884415 NLM ISO Abbreviation: Rev Esp Cir Ortop Traumatol Subsets: PubMed not MEDLINE; MEDLINE
أسماء مطبوعة: Original Publication: Barcelona : Elsevier Doyma
مستخلص: Introduction: Topical tranexamic acid (TXA) has been shown to decrease blood loss in knee and hip arthroplasty. Despite there is evidence about its effectiveness when administered intravenous, its effectiveness and optimal dose when used topically have not been established. We hypothesised that the use of 1.5g (30mL) of topical TXA could decrease the amount of blood loss in patients after reverse total shoulder arthroplasty (RTSA).
Material and Methods: One hundred and seventy-seven patients receiving a RSTA for arthropathy or fracture were retrospectively reviewed. Preoperative-to-postoperative change in haemoglobin (ΔHb) and hematocrit (ΔHct) level drain volume output, length of stay and complications were evaluated for each patient.
Results: Patients receiving TXA has significant less drain output in both for arthropathy (ARSA) (104 vs. 195mL, p=0.004) and fracture (FRSA) (47 vs. 79mL, p=0.01). Systemic blood loss was slightly lower in TXA group, but this was not statistically significant (ARSA, ΔHb 1.67 vs. 1.90mg/dL, FRSA 2.61 vs. 2.7mg/dL, p=0.79). This was also observed in hospital length of stay (ARSA 2.0 vs. 2.3 days, p=0.34; 2.3 vs. 2.5, p=0.56) and need of transfusion (0% AIHE; AIHF 5% vs. 7%, p=0.66). Patients operated for a fracture had a higher rate of complications (7% vs. 15.6%, p=0.04). There were no adverse events related to TXA administration.
Conclusion: Topical use of 1.5g of TXA decreases blood loss, especially on the surgical site without associated complications. Thus, haematoma decrease could avoid the systematic use of postoperative drains after reverse shoulder arthroplasty.
(Copyright © 2023 SECOT. Publicado por Elsevier España, S.L.U. All rights reserved.)
فهرسة مساهمة: Keywords: Artropatía de hombro; Artroplastia de hombro; Blood; Fractura de húmero proximal; Proximal humeral fracture; Sangre; Shoulder arthropathy; Shoulder arthroplasty; Tranexamic acid; Ácido tranexámico
تواريخ الأحداث: Date Created: 20230613 Latest Revision: 20231031
رمز التحديث: 20231215
DOI: 10.1016/j.recot.2023.06.010
PMID: 37311478
قاعدة البيانات: MEDLINE
الوصف
تدمد:1988-8856
DOI:10.1016/j.recot.2023.06.010