دورية أكاديمية
Phytobioactive compounds as therapeutic agents for human diseases: A review.
| العنوان: | Phytobioactive compounds as therapeutic agents for human diseases: A review. |
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| المؤلفون: | Riaz M; Department of Allied Health Sciences University of Sargodha Sargodha Pakistan., Khalid R; Department of Biochemistry University of Agriculture Faisalabad Pakistan., Afzal M; Hill Fruit Research Station Sunny Bank Murree Pakistan., Anjum F; Department of Chemistry Government College University Faisalabad Pakistan., Fatima H; Department of Biochemistry University of Agriculture Faisalabad Pakistan.; Department of Basic and Applied Chemistry, Faculty of Science and Technology University of Central Punjab Lahore Pakistan., Zia S; Department of Biochemistry University of Agriculture Faisalabad Pakistan., Rasool G; Department of Allied Health Sciences University of Sargodha Sargodha Pakistan., Egbuna C; Africa Centre of Excellence in Public Health and Toxicological Research (ACE-PUTOR), Nutritional Biochemistry and Toxicology Unit University of Port-Harcourt Port Harcourt Nigeria., Mtewa AG; Chemistry Section, Malawi Institute of Technology Malawi University of Science and Technology Limbe Malawi., Uche CZ; Department of Medical Biochemistry and Molecular Biology, Faculty of Basic Medical Sciences University of Nigeria Enugu Nigeria., Aslam MA; Insitute of Microbiology University of Agriculture Faisalabad Pakistan. |
| المصدر: | Food science & nutrition [Food Sci Nutr] 2023 Apr 17; Vol. 11 (6), pp. 2500-2529. Date of Electronic Publication: 2023 Apr 17 (Print Publication: 2023). |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101605473 Publication Model: eCollection Cited Medium: Print ISSN: 2048-7177 (Print) Linking ISSN: 20487177 NLM ISO Abbreviation: Food Sci Nutr Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Malden, MA : John Wiley & Sons, [2012]- |
| مستخلص: | Phytobioactive compounds are plant secondary metabolites and bioactive compounds abundantly present in medicinal plants and have remarkable therapeutic potential. Oxidative stress and antibiotic resistance are major causes of present-day ailments such as diabetes, atherosclerosis, cardiovascular disorders, cancer, and inflammation. The data for this review were collected from Google Scholar, PubMed, Directory of Open Access Journals (DOAJ), and Science Direct by using keywords: "Medicinal plants, Phytobioactive compounds, Polyphenols, Alkaloids, Carotenoids etc." Several studies have reported the pharmacological and therapeutic potential of the phytobioactives. Polyphenols, alkaloids, terpenes, and polysaccharides isolated from medicinal plants showed remarkable antioxidant, anticancer, cytotoxic, anti-inflammatory, cardioprotective, hepatoprotective, immunomodulatory, neuroprotective, and antidiabetic activities. This literature review was planned to provide comprehensive insight into the biopharmacological and therapeutic potential of phytobioactive compounds. The techniques used for the extraction and isolation of phytobioactive compounds, and bioassays required for their biological activities such as antioxidant, antimicrobial, anti-inflammatory, and cytotoxic activities, have been discussed. Characterization techniques for the structural elucidation of phytobioactive compounds such as HPLC, TLC, FTIR, GC-MS/MS, and NMR have also been discussed. This review concludes that phytobioactive compounds may be used as potential alternative to synthetic compounds as therapeutic agents for the treatment of various diseases. Competing Interests: The authors declared no conflict of interest. (© 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.) |
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| فهرسة مساهمة: | Keywords: alkaloids; medicinal plants; phytobioactive compounds; polyphenols; terpenoids |
| تواريخ الأحداث: | Date Created: 20230616 Latest Revision: 20231101 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC10261751 |
| DOI: | 10.1002/fsn3.3308 |
| PMID: | 37324906 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2048-7177 |
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| DOI: | 10.1002/fsn3.3308 |