دورية أكاديمية
ZnO and Au nanoparticles supported highly sensitive and selective electrochemical sensor based on molecularly imprinted polymer for sulfaguanidine and sulfamerazine detection.
| العنوان: | ZnO and Au nanoparticles supported highly sensitive and selective electrochemical sensor based on molecularly imprinted polymer for sulfaguanidine and sulfamerazine detection. |
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| المؤلفون: | Koçak İ; Zonguldak Bülent Ecevit University Faculty of Pharmacy, Zonguldak, Turkey. Electronic address: izzetkocak@beun.edu.tr. |
| المصدر: | Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2023 Sep 20; Vol. 234, pp. 115518. Date of Electronic Publication: 2023 Jun 08. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2006->: London : Elsevier Science Original Publication: Oxford ; New York : Pergamon Press, c1983- |
| مواضيع طبية MeSH: | Zinc Oxide* , Metal Nanoparticles*/chemistry , Molecular Imprinting*/methods, Humans ; Molecularly Imprinted Polymers ; Sulfamerazine ; Sulfaguanidine ; Gold/chemistry ; Reproducibility of Results ; Electrochemical Techniques/methods ; Electrodes ; Limit of Detection |
| مستخلص: | This study aimed to develop a molecularly imprinted polymer (MIP) sensor using electropolymerization of thiophene acetic acid monomer around template molecules, sulfaguanidine (SGN) and sulfamerazine (SMR), for selective and sensitive detection of both antibiotics. Au nanoparticles were then deposited on the modified electrode surface, and SGN and SMR were extracted from the resulting layer. Surface characterization, changes in the oxidation peak current of both analytes, and investigation of the electrochemical properties of the MIP sensor were examined using scanning electron microscopy, cyclic voltammetry, and differential pulse voltammetry. The developed MIP sensor with Au nanoparticles showed a detection limit of 0.030 µmol L -1 and 0.046 µmol L -1 for SGN and SMR, respectively, with excellent selectivity in the presence of interferents. The sensor was successfully used for SGN and SMR analysis in human fluids, including blood serum and urine, with excellent stability and reproducibility. Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2023 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: AuNP; MIP; Sulfaguanidine; Sulfamerazine; ZnO |
| المشرفين على المادة: | 0 (Molecularly Imprinted Polymers) UR1SAB295F (Sulfamerazine) 15XQ8043FN (Sulfaguanidine) 7440-57-5 (Gold) SOI2LOH54Z (Zinc Oxide) |
| تواريخ الأحداث: | Date Created: 20230619 Date Completed: 20230828 Latest Revision: 20230828 |
| رمز التحديث: | 20230828 |
| DOI: | 10.1016/j.jpba.2023.115518 |
| PMID: | 37336038 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-264X |
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| DOI: | 10.1016/j.jpba.2023.115518 |