مراجعة

Gingival metastasis of angiosarcoma of the breast as a first manifestation of spreading disease: Case report and review of the literature.

التفاصيل البيبلوغرافية
العنوان: Gingival metastasis of angiosarcoma of the breast as a first manifestation of spreading disease: Case report and review of the literature.
المؤلفون: Mota ME; Department of Stomatology, A.C.Camargo Cancer Center, São Paulo, Brazil., Tomo S; Department of Stomatology, A.C.Camargo Cancer Center, São Paulo, Brazil., Alves FA; Department of Stomatology, A.C.Camargo Cancer Center, São Paulo, Brazil., Pellissari GA; Department of Anatomic Pathology, A.C.Camargo Cancer Center, São Paulo, Brazil., do Nascimento AG; Department of Anatomic Pathology, A.C.Camargo Cancer Center, São Paulo, Brazil., Lopes RN; Department of Stomatology, A.C.Camargo Cancer Center, São Paulo, Brazil.
المصدر: Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry [Spec Care Dentist] 2024 Mar-Apr; Vol. 44 (2), pp. 458-464. Date of Electronic Publication: 2023 Jun 21.
نوع المنشور: Review; Case Reports
اللغة: English
بيانات الدورية: Publisher: American Dental Association Country of Publication: United States NLM ID: 8103755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1754-4505 (Electronic) Linking ISSN: 02751879 NLM ISO Abbreviation: Spec Care Dentist
أسماء مطبوعة: Original Publication: [Chicago : American Dental Association, c1981-
مواضيع طبية MeSH: Hemangiosarcoma*/diagnosis , Hemangiosarcoma*/therapy , Hemangiosarcoma*/pathology , Breast Neoplasms*, Female ; Humans ; Adult ; Gingiva/pathology
مستخلص: Background: Angiosarcoma is an aggressive malignant neoplasm of vascular origin. Oral metastases of angiosarcoma are rare and have a non-specific clinical presentation, thus the diagnosis may be challenging.
Case Report: Herein we report a case of a 34-year-old female patient after treatment of a high-grade angiosarcoma of the breast, who presented an asymptomatic bleeding purplish nodule in the maxillary interdental papilla between the first and second premolar. A biopsy was performed, and the histological examination revealed infiltration by malignant neoplasm of epithelioid and fusocellular pattern. Immunohistochemical analysis demonstrated that neoplastic cells were positive for ERG and CD31, and negative for cytokeratins AE1/AE3, confirming the diagnosis of metastatic angiosarcoma. After investigation, multiple metastases were discovered. The patient is under management with chemotherapy and palliative radiotherapy for the bone lesions.
Conclusion: Metastases should be considered in the differential diagnosis of oral lesions in patients with a previous history of cancer. Due to the morphology of angiosarcomas, the metastatic lesions may resemble benign vascular lesions, therefore, biopsy is mandatory to exclude malignancy.
(© 2023 Special Care Dentistry Association and Wiley Periodicals LLC.)
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فهرسة مساهمة: Keywords: angiosarcoma; metastasis; oral
SCR Disease Name: Angiosarcoma of the breast
تواريخ الأحداث: Date Created: 20230621 Date Completed: 20240315 Latest Revision: 20240315
رمز التحديث: 20240315
DOI: 10.1111/scd.12896
PMID: 37341541
قاعدة البيانات: MEDLINE
الوصف
تدمد:1754-4505
DOI:10.1111/scd.12896