دورية أكاديمية
Pregabalin Qualitative Detection in Turkish Forensic Cases Between 2017 to 2018.
| العنوان: | Pregabalin Qualitative Detection in Turkish Forensic Cases Between 2017 to 2018. |
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| المؤلفون: | Teker C; The Ministry of Justice, Council of Forensic Medicine, İ̇zmir, Turkey., Aslan R; Ege University, Institute on Drug Abuse, Toxicology and Pharmaceutical Science, Izmir, Turkey., İpekçi C; The Ministry of Justice, Council of Forensic Medicine, İ̇zmir, Turkey., Tokdemir M; The Ministry of Justice, Council of Forensic Medicine, İ̇zmir, Turkey.; Department of Forensic Medicine, Izmir Katip Çelebi University, Izmir, Turkey., Akgür SA; Ege University, Institute on Drug Abuse, Toxicology and Pharmaceutical Science, Izmir, Turkey. |
| المصدر: | Journal of psychoactive drugs [J Psychoactive Drugs] 2024 Jul-Aug; Vol. 56 (3), pp. 380-386. Date of Electronic Publication: 2023 Jun 21. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: United States NLM ID: 8113536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-9777 (Electronic) Linking ISSN: 02791072 NLM ISO Abbreviation: J Psychoactive Drugs Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <1997- > : Boca Raton : Taylor & Francis Original Publication: San Francisco, Calif. : Published by Haight-Ashbury Publications in association with the Haight-Ashbury Free Medical Clinic, c1981- |
| مواضيع طبية MeSH: | Pregabalin* , Substance Abuse Detection*/methods, Humans ; Turkey ; Male ; Adult ; Female ; Young Adult ; Middle Aged ; Adolescent ; Aged ; Substance-Related Disorders/epidemiology ; Illicit Drugs ; Aged, 80 and over |
| مستخلص: | Pregabalin (PGB) has been commonly subjected to diversion, from being a prescription drug to a recreational drug. In this study, pregabalin use (which is one of the substances subject to control in Turkey) and the concomitant use of other substances in cases admitted to the Izmir Forensic Medicine Institute was evaluated. Samples from 15,259 cases were screened, between June 2017 and December 2018, for the presence of PGB, and PGB positive cases were further analyzed. Of all cases screened, PGB was detected in 3.2% ( n = 487). The mean age of PGB positive cases was 29.24 ± 10.34 years old (min: 14, max: 84), and 94% of them were male. Cannabis metabolite THC-COOH was the most common substance detected in the blood samples following PGB. Overall, 8 other substances were commonly used along with PGB. These substances were cannabis, morphine, hydromorphone, codeine, hydrocodone, heroin, paracetamol, and naproxen. Finally, we observed similar results in urine analysis. This research provides systematic data for PGB use in forensic cases in Turkey. The study findings indicate that PGB and multiple drug use increased over time, and providers should be particularly careful when prescribing PGB. |
| فهرسة مساهمة: | Keywords: LC-MS/MS; Pregabalin; forensic toxicology; prescription drug abuse |
| المشرفين على المادة: | 55JG375S6M (Pregabalin) 0 (Illicit Drugs) |
| تواريخ الأحداث: | Date Created: 20230621 Date Completed: 20240701 Latest Revision: 20240701 |
| رمز التحديث: | 20240702 |
| DOI: | 10.1080/02791072.2023.2226138 |
| PMID: | 37343948 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 2159-9777 |
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| DOI: | 10.1080/02791072.2023.2226138 |