دورية أكاديمية
Greater Improvement in Obesity Among Children With Prediabetes in a Clinical Weight Management Program.
| العنوان: | Greater Improvement in Obesity Among Children With Prediabetes in a Clinical Weight Management Program. |
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| المؤلفون: | Tester JM; Department of Pediatrics, UCSF Benioff Children's Hospital Oakland, Oakland, CA, USA.; Department of Pediatrics, University of California, San Francisco School of Medicine, San Francisco, CA, USA., Xiao L; Department of Epidemiology and Population Health, Stanford School of Medicine, Palo Alto, CA, USA., Chau CA; Department of Nutritional science, University of California, Berkeley, CA, USA., Tinajero-Deck L; Department of Pediatrics, UCSF Benioff Children's Hospital Oakland, Oakland, CA, USA.; Department of Pediatrics, University of California, San Francisco School of Medicine, San Francisco, CA, USA., Srinivasan S; Department of Pediatrics, University of California, San Francisco School of Medicine, San Francisco, CA, USA., Rosas LG; Department of Epidemiology and Population Health, Stanford School of Medicine, Palo Alto, CA, USA. |
| المصدر: | Childhood obesity (Print) [Child Obes] 2024 May; Vol. 20 (4), pp. 262-269. Date of Electronic Publication: 2023 Jun 21. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 101542497 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2153-2176 (Electronic) Linking ISSN: 21532168 NLM ISO Abbreviation: Child Obes Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New Rochelle, NY : Mary Ann Liebert |
| مواضيع طبية MeSH: | Prediabetic State*/therapy , Pediatric Obesity*/therapy , Weight Reduction Programs*/methods, Humans ; Male ; Female ; Child ; Adolescent ; Retrospective Studies ; Glycated Hemoglobin/analysis ; Body Mass Index ; Weight Loss/physiology ; Longitudinal Studies |
| مستخلص: | Background: There is a range of responses among individuals seen for medical management of their obesity. This retrospective analysis of longitudinal data considers the relationship between identified prediabetes and subsequent weight change among children (8-17 years) in a weight management clinic. Methods: Analysis included 733 patients (2687 visits in 2008-2016) with overweight and obesity (but not diabetes) whose referral laboratories included a hemoglobin A1c (HbA1c) within 90 days. Mixed-effects modeling examined the association between baseline prediabetes (serum HbA1c 5.7%-6.4%) and growth curve of percentage of the 95th percentile for BMI (%BMIp95). Random effects (individual growth curves) and fixed effects (prediabetes status, starting age and %BMIp95, sex, race/ethnicity, and linear slope and quadratic term of months since the initial visit) were modeled. Interactions between prediabetes and elapsed time estimated the influence of a recent prediabetic-range HbA1c on weight during the subsequent 12 months. Results: Mean %BMIp95 was 125.5% (SD 22.5), corresponding to severe obesity, and 35% had prediabetes. Adjusted monthly decrease in %BMIp95 was stronger for children with prediabetes compared with the peers in this clinic (slope: -0.62, standard error 0.10, p < 0.001). Conclusion: There was greater weight improvement among children with prediabetes compared with their peers with normal HbA1c. |
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| معلومات مُعتمدة: | R01 DK140186 United States DK NIDDK NIH HHS; R01 MD016738 United States MD NIMHD NIH HHS |
| فهرسة مساهمة: | Keywords: %BMIp95; clinical management; longitudinal; prediabetes |
| المشرفين على المادة: | 0 (Glycated Hemoglobin) |
| تواريخ الأحداث: | Date Created: 20230622 Date Completed: 20240610 Latest Revision: 20240714 |
| رمز التحديث: | 20240714 |
| مُعرف محوري في PubMed: | PMC11238840 |
| DOI: | 10.1089/chi.2022.0234 |
| PMID: | 37347933 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2153-2176 |
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| DOI: | 10.1089/chi.2022.0234 |