تقرير
Rare Presentation of Disseminated Gout Nodulosis and Chronic Inflammatory Arthritis.
| العنوان: | Rare Presentation of Disseminated Gout Nodulosis and Chronic Inflammatory Arthritis. |
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| المؤلفون: | Sami F; John H. Stroger Jr. Hospital of Cook County, 1969 W Ogden Ave, Chicago, IL 60612, USA., Sami SA; Trinity Health Oakland Campus, 44405 Woodward Ave, Pontiac, MI 48341, USA., Arora S; John H. Stroger Jr. Hospital of Cook County, 1969 W Ogden Ave, Chicago, IL 60612, USA. |
| المصدر: | Case reports in rheumatology [Case Rep Rheumatol] 2023 Jun 14; Vol. 2023, pp. 8083212. Date of Electronic Publication: 2023 Jun 14 (Print Publication: 2023). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 101585353 Publication Model: eCollection Cited Medium: Print ISSN: 2090-6889 (Print) Linking ISSN: 20906897 NLM ISO Abbreviation: Case Rep Rheumatol Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, NY : Hindawi Pub. Corp., [2011]- |
| مستخلص: | Background: Gout is an inflammatory arthritis caused by monosodium urate (MSU) deposition. Acute gout is a dramatic painful swelling of the joint; however, MSU can deposit in other tissues as well, including skin, gastrointestinal tract, and bones over time. Disseminated tophi in the skin are a rare presentation of gout known as gout nodulosis. We present a case of gout nodulosis with subcutaneous diffuse miliary nodules in nonarticular areas with concurrent findings suggestive of chronic inflammatory arthritis. Case Presentation . A 39-year-old patient presented with intermittent painful swelling in multiple joints with prolonged morning stiffness. On exam, synovitis was present in multiple proximal interphalangeal joints, wrists, elbows, and knees. Chronic raised pearly nodular rash and swellings on extensor aspects of arms, legs, and anterior abdomen were noticeable. He had negative rheumatoid factor and anti-CCP antibody, C-reactive protein of 0.23 mg/dL, erythrocyte sedimentation rate of 37 mm/hr, and uric acid of 10.6 mg/dL. Hand X-rays revealed severe periarticular osteopenia and joint space narrowing in several joints. Musculoskeletal ultrasound showed a double contour sign at multiple joints and a tophaceous deposit over the olecranon fossa. The biopsy of the nodular rash was consistent with tophi. He was diagnosed with chronic tophaceous gout with skin nodulosis and possible overlap of seronegative rheumatoid arthritis given his X-ray findings. Conclusion: This case discusses one of the rare presentations of gout with disseminated gouty tophi in the skin to raise clinical awareness. The clinical dilemma of the overlap of gout and rheumatoid arthritis posing a diagnostic challenge for clinicians is also highlighted. Competing Interests: The authors declare that they have no conflicts of interest. (Copyright © 2023 Faria Sami et al.) |
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| تواريخ الأحداث: | Date Created: 20230623 Latest Revision: 20230701 |
| رمز التحديث: | 20230701 |
| مُعرف محوري في PubMed: | PMC10284652 |
| DOI: | 10.1155/2023/8083212 |
| PMID: | 37350776 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2090-6889 |
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| DOI: | 10.1155/2023/8083212 |