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Clinicopathologic analysis of a case of small cell lung carcinoma metastatic to the retina.

التفاصيل البيبلوغرافية
العنوان: Clinicopathologic analysis of a case of small cell lung carcinoma metastatic to the retina.
المؤلفون: Alabi RO; Department of Ophthalmology, Wayne & Gladys Valley Center for Vision, University of California, San Francisco, San Francisco, CA, USA., Haq Z; Department of Ophthalmology, Wayne & Gladys Valley Center for Vision, University of California, San Francisco, San Francisco, CA, USA., Bloomer MM; Ophthalmic Pathology Service, Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA., Afshar AR; Ocular Oncology Service and Vitreoretinal Service, Department of Ophthalmology, Wayne & Gladys Valley Center for Vision, University of California, San Francisco, San Francisco, CA, USA.; Hellen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.
المصدر: American journal of ophthalmology case reports [Am J Ophthalmol Case Rep] 2023 Jun 05; Vol. 31, pp. 101863. Date of Electronic Publication: 2023 Jun 05 (Print Publication: 2023).
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 101679941 Publication Model: eCollection Cited Medium: Internet ISSN: 2451-9936 (Electronic) Linking ISSN: 24519936 NLM ISO Abbreviation: Am J Ophthalmol Case Rep Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: [Atlanta] : Elsevier, Inc. [2016]-
مستخلص: Purpose: Tumor metastases to the retina are a relatively rare occurrence. We report a unique case of retinal metastasis of a systemic malignancy with clinical and histopathologic correlations.
Observations: A 62-year-old female with a history of stage IV small cell carcinoma of the lung (SCC, status post chemotherapy and maintenance immunotherapy) presented with hand motions vision and vitreous hemorrhage, status post prior vitrectomy and biopsy that was non-diagnostic. She was found to have unilateral retinal metastatic tumor and underwent a repeat vitrector-assisted biopsy which confirmed the diagnosis. The eye became blind and painful due to recurrent non-clearing vitreous hemorrhage and ghost cell glaucoma and was enucleated. Detailed histopathologic analysis of the globe confirmed small cell carcinoma metastatic to the retina and vitreous cavity and sparing the choroid.
Conclusions and Importance: This case demonstrates the importance of maintaining a high index of suspicion for metastasis in patients with a known history of malignancy who present with new vitreoretinal lesions.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2023 The Authors.)
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فهرسة مساهمة: Keywords: Carcinoma; Clinicopathologic correlation; Masquerade syndrome; Retinal metastasis; Vitreous hemorrhage
تواريخ الأحداث: Date Created: 20230623 Latest Revision: 20230701
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10282170
DOI: 10.1016/j.ajoc.2023.101863
PMID: 37351340
قاعدة البيانات: MEDLINE
الوصف
تدمد:2451-9936
DOI:10.1016/j.ajoc.2023.101863