دورية أكاديمية
أعرض في EDS

Arterial Blood Gases and Acid-Base Regulation.

التفاصيل البيبلوغرافية
العنوان: Arterial Blood Gases and Acid-Base Regulation.
المؤلفون: Sanghavi SF; Division of Nephrology, Department of Medicine, University of Washington, Puget Sound Veterans Affairs Healthcare System, Seattle, Washington., Swenson ER; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Puget Sound Veterans Affairs Healthcare System, Seattle, Washington.
المصدر: Seminars in respiratory and critical care medicine [Semin Respir Crit Care Med] 2023 Oct; Vol. 44 (5), pp. 612-626. Date of Electronic Publication: 2023 Jun 27.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Thieme Medical Publishers Country of Publication: United States NLM ID: 9431858 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-9048 (Electronic) Linking ISSN: 10693424 NLM ISO Abbreviation: Semin Respir Crit Care Med Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York : Thieme Medical Publishers, c1994-
مواضيع طبية MeSH: Acid-Base Imbalance*/complications , Acid-Base Imbalance*/metabolism , Acidosis*/etiology , Alkalosis*/complications, Humans ; Hydrogen-Ion Concentration ; Acid-Base Equilibrium ; Carbon Dioxide
مستخلص: Disorders of acid-base status are common in the critically ill and prompt recognition is central to clinical decision making. The bicarbonate/carbon dioxide buffer system plays a pivotal role in maintaining acid-base homeostasis, and measurements of pH, PCO 2 , and HCO 3 - are routinely used in the estimation of metabolic and respiratory disturbance severity. Hypoventilation and hyperventilation cause primary respiratory acidosis and primary respiratory alkalosis, respectively. Metabolic acidosis and metabolic alkalosis have numerous origins, that include alterations in acid or base intake, body fluid losses, abnormalities of intermediary metabolism, and renal, hepatic, and gastrointestinal dysfunction. The concept of the anion gap is used to categorize metabolic acidoses, and urine chloride excretion helps define metabolic alkaloses. Both the lungs and kidneys employ compensatory mechanisms to minimize changes in pH caused by various physiologic and disease disturbances. Treatment of acid-base disorders should focus primarily on correcting the underlying cause and the hemodynamic and electrolyte derangements that ensue. Specific therapies under certain conditions include renal replacement therapy, mechanical ventilation, respiratory stimulants or depressants, and inhibition of specific enzymes in intermediary metabolism disorders.
Competing Interests: None declared.
(Thieme. All rights reserved.)
المشرفين على المادة: 142M471B3J (Carbon Dioxide)
تواريخ الأحداث: Date Created: 20230627 Date Completed: 20231012 Latest Revision: 20231018
رمز التحديث: 20240628
DOI: 10.1055/s-0043-1770341
PMID: 37369215
قاعدة البيانات: MEDLINE
الوصف
تدمد:1098-9048
DOI:10.1055/s-0043-1770341