دورية أكاديمية
Oocyte metabolic function, lipid composition, and developmental potential are altered by diet in older mares.
| العنوان: | Oocyte metabolic function, lipid composition, and developmental potential are altered by diet in older mares. |
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| المؤلفون: | Catandi GD; Equine Reproduction Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA., LiPuma L; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA., Obeidat YM; Electronic Engineering Department, Hijjawi Faculty for Engineering Technology, Yarmouk University, Irbid, Jordan., Maclellan LJ; Equine Reproduction Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA., Broeckling CD; Proteomics and Metabolomics Facility, Colorado State University, Fort Collins, Colorado, USA., Chen T; Department of Electrical and Computer Engineering, Colorado State University, Fort Collins, Colorado, USA.; School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, USA., Chicco AJ; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA., Carnevale EM; Equine Reproduction Laboratory, Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA.; Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA. |
| المصدر: | Reproduction (Cambridge, England) [Reproduction] 2022 Jan 28; Vol. 163 (4), pp. 183-198. Date of Electronic Publication: 2022 Jan 28 (Print Publication: 2022). |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Published for the Society for Reproduction and Fertility by BioScientifica Country of Publication: England NLM ID: 100966036 Publication Model: eCollection Cited Medium: Internet ISSN: 1741-7899 (Electronic) Linking ISSN: 14701626 NLM ISO Abbreviation: Reproduction Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2004->: Bristol, UK : Published for the Society for Reproduction and Fertility by BioScientifica Original Publication: Cambridge, UK : Journals of Reproduction and Fertility, Ltd. c2001- |
| مواضيع طبية MeSH: | Semen* , Oocytes*, Horses ; Animals ; Female ; Male ; Diet/veterinary ; Fatty Acids ; Antioxidants ; Fatty Acids, Omega-6 |
| مستخلص: | Dietary supplementation is the most feasible method to improve oocyte function and developmental potential in vivo . During three experiments, oocytes were collected from maturing, dominant follicles of older mares to determine whether short-term dietary supplements can alter oocyte metabolic function, lipid composition, and developmental potential. Over approximately 8 weeks, control mares were fed hay (CON) or hay and grain products (COB). Treated mares received supplements designed for equine wellness and gastrointestinal health, flaxseed oil, and a proprietary blend of fatty acid and antioxidant support (reproductive support supplement (RSS)) intended to increase antioxidant activity and lipid oxidation. RSS was modified for individual experiments with additional antioxidants or altered concentrations of n-3 to n-6 fatty acids. Oocytes from mares supplemented with RSS when compared to COB had higher basal oxygen consumption, indicative of higher aerobic metabolism, and proportionately more aerobic to anaerobic metabolism. In the second experiment, oocytes collected from the same mares prior to (CON) and after approximately 8 weeks of RSS supplementation had significantly reduced oocyte lipid abundance. In the final experiment, COB was compared to RSS supplementation, including RSS modified to proportionately reduce n-3 fatty acids and increase n-6 fatty acids. The ability of sperm-injected oocytes to develop into blastocysts was higher for RSS, regardless of fatty acid content, than for COB. We demonstrated that short-term diet supplementation can directly affect oocyte function in older mares, resulting in oocytes with increased metabolic activity, reduced lipid content, and increased developmental potential. (© The authors.) |
| References: | Theriogenology. 2008 May;69(8):940-5. (PMID: 18358523) Comp Biochem Physiol A Comp Physiol. 1988;91(4):827-35. (PMID: 2907450) Cells. 2020 Apr 17;9(4):. (PMID: 32316494) Biotechnol J. 2006 Apr;1(4):420-39. (PMID: 16892270) N Engl J Med. 2003 Jun 26;348(26):2656-68. (PMID: 12826641) Curr Opin Obstet Gynecol. 2015 Jun;27(3):175-81. (PMID: 25719756) Hum Reprod. 2000 Jul;15 Suppl 2:189-98. (PMID: 11041524) J Equine Vet Sci. 2020 Jun;89:103022. (PMID: 32563447) Biol Reprod. 2019 Apr 1;100(4):971-981. (PMID: 30476005) J Sci Med Sport. 2014 Jul;17(4):399-403. (PMID: 23809839) Mitochondrion. 2011 Sep;11(5):797-813. (PMID: 20933103) Fertil Steril. 2017 Apr;107(4):840-847. (PMID: 28292619) Theriogenology. 2014 Apr 15;81(7):966-73. (PMID: 24576708) Biofactors. 2018 Jan;44(1):69-82. (PMID: 29210129) Vet Clin North Am Equine Pract. 2016 Dec;32(3):379-399. (PMID: 27726987) Arch Tierernahr. 1999;52(2):115-38. (PMID: 10548966) Lipids. 1999 Sep;34(9):951-63. (PMID: 10574660) Clin Exp Pharmacol Physiol. 2013 Sep;40(9):671-81. (PMID: 23745944) Reprod Fertil Dev. 2015 May;27(4):572-82. (PMID: 25798589) Theriogenology. 2011 Apr 15;75(7):1319-26. (PMID: 21295825) J Equine Vet Sci. 2019 Sep;80:20-26. (PMID: 31443828) J Assist Reprod Genet. 2017 May;34(5):573-580. (PMID: 28190213) Hum Reprod Update. 2021 Jan 4;27(1):27-47. (PMID: 33020823) Am J Obstet Gynecol. 2018 Apr;218(4):379-389. (PMID: 28844822) Biol Reprod. 2007 Feb;76(2):327-35. (PMID: 17035641) BMC Bioinformatics. 2008 Nov 28;9:504. (PMID: 19040729) Anal Chem. 2006 Feb 1;78(3):779-87. (PMID: 16448051) Reproduction. 2014 Jul;148(1):R15-27. (PMID: 24760880) Syst Biol Reprod Med. 2013 Apr;59(2):91-8. (PMID: 23278116) Exp Biol Med (Maywood). 2003 Feb;228(2):160-6. (PMID: 12563022) Dev Biol. 2017 Jun 1;426(1):126-138. (PMID: 28438607) Biol Reprod. 2013 Jun 27;88(6):164. (PMID: 23616596) Front Med. 2018 Oct;12(5):518-524. (PMID: 29260383) Aging Cell. 2015 Oct;14(5):887-95. (PMID: 26111777) J Cell Physiol. 2019 Feb;234(2):1016-1029. (PMID: 30073662) Mol Reprod Dev. 2009 Sep;76(9):844-53. (PMID: 19455666) Sci Rep. 2020 Feb 26;10(1):3493. (PMID: 32103136) Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1198-206. (PMID: 17684106) Biol Reprod. 2016 Jan;94(1):15. (PMID: 26632608) Biol Reprod. 2012 Feb 09;86(2):27. (PMID: 22034525) Fertil Steril. 2020 Feb;113(2):260-269. (PMID: 31870562) Reprod Fertil Dev. 2019 Jan;31(12):1758-1770. (PMID: 31718765) Curr Top Dev Biol. 2007;77:51-83. (PMID: 17222700) Biol Reprod. 2015 Jan;92(1):16. (PMID: 25297544) Cell Mol Life Sci. 2015 Jan;72(2):251-71. (PMID: 25280482) Front Cell Dev Biol. 2020 Nov 19;8:593005. (PMID: 33330475) Biol Reprod. 2010 Jul;83(1):52-62. (PMID: 20130269) Maturitas. 2016 Oct;92:134-142. (PMID: 27621251) J Assist Reprod Genet. 2017 Dec;34(12):1595-1607. (PMID: 28900834) J Equine Vet Sci. 2021 Jan;96:103303. (PMID: 33349408) Theriogenology. 2018 Oct 1;119:114-120. (PMID: 30006126) Biochem J. 2011 Apr 15;435(2):297-312. (PMID: 21726199) Theriogenology. 2017 Nov;103:98-103. (PMID: 28779614) Reproduction. 2021 Apr;161(4):399-409. (PMID: 33539317) BMC Med. 2012 May 21;10:50. (PMID: 22613931) Theriogenology. 2008 Jan 1;69(1):23-30. (PMID: 17976712) Anim Reprod Sci. 2012 Sep;134(1-2):69-75. (PMID: 22917873) Reprod Biomed Online. 2018 Jun;36(6):686-697. (PMID: 29598846) J Physiol Biochem. 2013 Jun;69(2):165-75. (PMID: 22941749) Equine Vet J Suppl. 1997 Dec;(25):12-6. (PMID: 9593520) Aging Cell. 2012 Dec;11(6):1046-54. (PMID: 22978268) Lancet. 1991 Jun 8;337(8754):1375-7. (PMID: 1674764) J Dairy Sci. 2010 Feb;93(2):529-45. (PMID: 20105525) Animals (Basel). 2020 May 19;10(5):. (PMID: 32438699) Biosens Bioelectron. 2019 May 15;133:39-47. (PMID: 30909011) J Biol Chem. 2018 May 4;293(18):6659-6671. (PMID: 29540485) Adv Exp Med Biol. 2012;763:186-92. (PMID: 23397625) Int J Fertil Steril. 2019 Jan;12(4):316-323. (PMID: 30291693) Fertil Steril. 2016 Mar;105(3):548-559. (PMID: 26812244) Anim Reprod Sci. 2010 Jan;117(1-2):78-82. (PMID: 19473790) Reprod Fertil Dev. 2019 Mar;31(3):570-578. (PMID: 30423285) J Assist Reprod Genet. 2007 Feb-Mar;24(2-3):91-7. (PMID: 17216562) |
| معلومات مُعتمدة: | R21 HD097601 United States HD NICHD NIH HHS |
| المشرفين على المادة: | 0 (Fatty Acids) 0 (Antioxidants) 0 (Fatty Acids, Omega-6) |
| تواريخ الأحداث: | Date Created: 20230628 Date Completed: 20230630 Latest Revision: 20231104 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC8942336 |
| DOI: | 10.1530/REP-21-0351 |
| PMID: | 37379450 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1741-7899 |
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| DOI: | 10.1530/REP-21-0351 |