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Case report: Injected corticosteroids for treating leprosy isolated neuritis.

التفاصيل البيبلوغرافية
العنوان: Case report: Injected corticosteroids for treating leprosy isolated neuritis.
المؤلفون: Spitz CN; Leprosy Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.; Post-Graduate Program in Neurology, Federal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.; Pedro Ernesto University Hospital, Rio de Janeiro State University, Rio de Janeiro, Brazil., Pitta IJR; Leprosy Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.; Department of Neurology, Antonio Pedro University Hospital, Fluminense Federal University, Niteroi, Brazil., Andrade LR; Leprosy Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.; Post-Graduate Program in Neurology, Federal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.; Pedro Ernesto University Hospital, Rio de Janeiro State University, Rio de Janeiro, Brazil., Sales AM; Leprosy Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Sarno EN; Leprosy Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Villela NR; Pedro Ernesto University Hospital, Rio de Janeiro State University, Rio de Janeiro, Brazil., Pinheiro RO; Leprosy Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.; National Institute of Science and Technology on Neuroimmunomodulation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Jardim MR; Leprosy Laboratory, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.; Post-Graduate Program in Neurology, Federal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.; Pedro Ernesto University Hospital, Rio de Janeiro State University, Rio de Janeiro, Brazil.; National Institute of Science and Technology on Neuroimmunomodulation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
المصدر: Frontiers in medicine [Front Med (Lausanne)] 2023 Jun 15; Vol. 10, pp. 1202108. Date of Electronic Publication: 2023 Jun 15 (Print Publication: 2023).
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Lausanne, Switzerland : Frontiers Media S.A., [2014]-
مستخلص: One of the main manifestations of leprosy is peripheral nerve impairment. Early diagnosis and treatment are important to reduce the impact of neurological impairment, which can cause deformities and physical disabilities. Leprosy neuropathy can be acute or chronic, and neural involvement can occur before, during, or after multidrug therapy, and especially during reactional episodes when neuritis occurs. Neuritis causes loss of function in the nerves and can be irreversible if left untreated. The recommended treatment is corticosteroids, usually through an oral regimen at an immunosuppressive dose. However, patients with clinical conditions that restrict corticosteroid use or that have focal neural involvement may benefit from the use of ultrasound-guided perineural injectable corticosteroids. In this study, we report two cases that demonstrate how the treatment and follow-up of patients with neuritis secondary to leprosy, using new techniques, can be provided in a more individualized way. Nerve conduction studies in association with neuromuscular ultrasound were used to monitor the response to treatment with injected steroids, focusing on neural inflammation. This study provides new perspectives and options for this profile of patients.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2023 Spitz, Pitta, Andrade, Sales, Sarno, Villela, Pinheiro and Jardim.)
References: Ann Rehabil Med. 2015 Apr;39(2):176-82. (PMID: 25932413)
Neurotherapeutics. 2021 Oct;18(4):2337-2350. (PMID: 34799845)
Front Microbiol. 2021 Sep 10;12:698588. (PMID: 34566911)
Clin Dermatol. 2016 Jan-Feb;34(1):51-8. (PMID: 26773623)
J Neuropathol Exp Neurol. 2016 Mar;75(3):272-83. (PMID: 26888306)
Int J Lepr Other Mycobact Dis. 1966 Jul-Sep;34(3):255-73. (PMID: 5950347)
Lepr Rev. 2000 Sep;71(3):285-308. (PMID: 11105488)
JAMA. 1999 Aug 18;282(7):671-6. (PMID: 10517721)
Lepr Rev. 1994 Sep;65(3):190-203. (PMID: 8942150)
Arq Neuropsiquiatr. 2007 Dec;65(4A):969-73. (PMID: 18094856)
Expert Rev Clin Immunol. 2015 Mar;11(3):391-407. (PMID: 25666357)
BMJ. 1999 Oct 2;319(7214):884-6. (PMID: 10506042)
Aust N Z J Surg. 1997 Sep;67(9):643-4. (PMID: 9322705)
Ann Rheum Dis. 2001 Aug;60(8):813-4. (PMID: 11482310)
Indian J Lepr. 2012 Jan-Mar;84(1):9-15. (PMID: 23077778)
Mem Inst Oswaldo Cruz. 2013 May;108(3):. (PMID: 23778664)
Acta Neurol Scand. 2021 Aug;144(2):155-160. (PMID: 33899225)
Curr Sports Med Rep. 2016 Jan-Feb;15(1):20-2. (PMID: 26745165)
PLoS Negl Trop Dis. 2016 Nov 16;10(11):e0005111. (PMID: 27851766)
PLoS Negl Trop Dis. 2009 Aug 11;3(8):e498. (PMID: 19668356)
Lepr Rev. 2003 Dec;74(4):328-36. (PMID: 14750578)
Acta Neuropathol. 2015 May;129(5):653-67. (PMID: 25772973)
PLoS Negl Trop Dis. 2011 Apr 12;5(4):e1041. (PMID: 21532737)
فهرسة مساهمة: Keywords: case report; corticosteroid; leprosy; neuritis; ultrasound
تواريخ الأحداث: Date Created: 20230703 Latest Revision: 20230704
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10313350
DOI: 10.3389/fmed.2023.1202108
PMID: 37396908
قاعدة البيانات: MEDLINE
الوصف
تدمد:2296-858X
DOI:10.3389/fmed.2023.1202108