دورية أكاديمية
أعرض في EDS

Prefrontal cortex state representations shape human credit assignment.

التفاصيل البيبلوغرافية
العنوان: Prefrontal cortex state representations shape human credit assignment.
المؤلفون: Lamba A; Department of Cognitive Linguistic & Psychological Sciences, Brown University, Providence, United States., Nassar MR; Department of Neuroscience, Brown University, Providence, United States.; Carney Institute of Brain Sciences, Brown University, Providence, United States., FeldmanHall O; Department of Cognitive Linguistic & Psychological Sciences, Brown University, Providence, United States.; Carney Institute of Brain Sciences, Brown University, Providence, United States.
المصدر: ELife [Elife] 2023 Jul 03; Vol. 12. Date of Electronic Publication: 2023 Jul 03.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Cambridge, UK : eLife Sciences Publications, Ltd., 2012-
مواضيع طبية MeSH: Prefrontal Cortex*/diagnostic imaging , Learning*, Humans ; Reward ; Cues ; Decision Making
مستخلص: People learn adaptively from feedback, but the rate of such learning differs drastically across individuals and contexts. Here, we examine whether this variability reflects differences in what is learned. Leveraging a neurocomputational approach that merges fMRI and an iterative reward learning task, we link the specificity of credit assignment-how well people are able to appropriately attribute outcomes to their causes-to the precision of neural codes in the prefrontal cortex (PFC). Participants credit task-relevant cues more precisely in social compared vto nonsocial contexts, a process that is mediated by high-fidelity (i.e., distinct and consistent) state representations in the PFC. Specifically, the medial PFC and orbitofrontal cortex work in concert to match the neural codes from feedback to those at choice, and the strength of these common neural codes predicts credit assignment precision. Together this work provides a window into how neural representations drive adaptive learning.
Competing Interests: AL, MN, OF No competing interests declared
(© 2023, Lamba et al.)
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معلومات مُعتمدة: R01 MH126971 United States MH NIMH NIH HHS
فهرسة مساهمة: Keywords: RSA; credit assignment; fMRI; human; neuroscience; orbitofrontal cortex; prefrontal cortex; reinforcement learning
تواريخ الأحداث: Date Created: 20230703 Date Completed: 20230719 Latest Revision: 20240508
رمز التحديث: 20240508
مُعرف محوري في PubMed: PMC10351919
DOI: 10.7554/eLife.84888
PMID: 37399050
قاعدة البيانات: MEDLINE
الوصف
تدمد:2050-084X
DOI:10.7554/eLife.84888