دورية أكاديمية
Comparison of Intraaortic Balloon Pump and Impella 5.5 as Heart Transplant Bridging Strategies.
| العنوان: | Comparison of Intraaortic Balloon Pump and Impella 5.5 as Heart Transplant Bridging Strategies. |
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| المؤلفون: | Iyengar A; Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania., Rekhtman D; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Weingarten N; Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania., Song C; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Shin M; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Helmers MR; Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania., Kelly JJ; Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania., Cevasco M; Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania., Atluri P; Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: pavan.atluri@pennmedicine.upenn.edu. |
| المصدر: | The Annals of thoracic surgery [Ann Thorac Surg] 2023 Oct; Vol. 116 (4), pp. 811-817. Date of Electronic Publication: 2023 Jul 05. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 15030100R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-6259 (Electronic) Linking ISSN: 00034975 NLM ISO Abbreviation: Ann Thorac Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Boston. |
| مواضيع طبية MeSH: | Heart Transplantation* , Heart-Assist Devices*/adverse effects , Heart Failure*/surgery , Heart Failure*/etiology, Humans ; Treatment Outcome ; Intra-Aortic Balloon Pumping ; Retrospective Studies |
| مستخلص: | Background: Temporary mechanical circulatory support is increasingly utilized as a bridge to heart transplantation. The Impella 5.5 (Abiomed) has achieved anecdotal success as a bridge since receiving US Food and Drug Administration approval. The purpose of the current study was to compare waitlist and posttransplant outcomes of patients bridged with intraaortic balloon pumps (IABPs) to those receiving Impella 5.5 therapy. Methods: Patients listed for heart transplantation between October 2018 and December 2021 who received IABP or Impella 5.5 at any time during waitlist course were identified from the United Network for Organ Sharing database. Propensity-matched groups of recipients with each device were created. Competing-risks regression for mortality, transplantation, and removal from waitlist for illness was performed according to the method of Fine and Gray. Posttransplant survival was censored at 2 years. Results: Overall, 2936 patients were identified, of whom 2484 (85%) were supported with IABP and 452 (15%) received Impella 5.5. Patients with Impella 5.5 support had more functional impairment, higher wedge pressures, higher rates of preoperative diabetes and dialysis, and more ventilator support (all P < .05). Waitlist mortality was significantly worsened in the Impella group and transplantation was less frequent (P < .001). However, survival at 2 years after transplant was similar in both complete (90% vs 90%, P = .693) and propensity-matched cohorts (88% vs 83%, P = .874). Conclusions: Patients bridged with Impella 5.5 were sicker than IABP-bridged patients and less frequently transplanted; however, posttransplant outcomes were similar in propensity-matched cohorts. The role of these bridging strategies in patients listed for heart transplantation should be continually assessed with future allocation system changes. (Copyright © 2023 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.) |
| التعليقات: | Comment in: Ann Thorac Surg. 2023 Oct;116(4):817-818. (PMID: 37567374) |
| تواريخ الأحداث: | Date Created: 20230707 Date Completed: 20230925 Latest Revision: 20230928 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.athoracsur.2023.06.021 |
| PMID: | 37419173 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1552-6259 |
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| DOI: | 10.1016/j.athoracsur.2023.06.021 |