دورية أكاديمية
Evaluating Disparities in Colon Cancer Survival in American Indian/Alaskan Native Patients Using the National Cancer Database.
العنوان: | Evaluating Disparities in Colon Cancer Survival in American Indian/Alaskan Native Patients Using the National Cancer Database. |
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المؤلفون: | Nalluri H; Department of Surgery, University of Minnesota, Minneapolis, MN, USA., Marmor S; Department of Surgery, University of Minnesota, Minneapolis, MN, USA., Prathibha S; Department of Surgery, University of Minnesota, Minneapolis, MN, USA., Jenkins A; Department of Surgery, University of Minnesota, Minneapolis, MN, USA., Dindinger-Hill K; Department of Surgery, University of Minnesota, Minneapolis, MN, USA., Kihara M; Department of Surgery, University of Minnesota, Minneapolis, MN, USA., Sundberg MA; Department of Medicine, University of Minnesota, Minneapolis, MN, USA.; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Day LW; Division of Gastroenterology and Hepatology, University of California San Francisco, San Francisco, CA, USA., Owen MJ; Department of Family Medicine and BioBehavioral Health, University of Minnesota, Duluth, MN, USA.; Center for American Indian and Minority Health, University of Minnesota, Duluth, MN, USA., Lowry AC; Department of Surgery, University of Minnesota, Minneapolis, MN, USA., Tuttle TM; Department of Surgery, University of Minnesota, Minneapolis, MN, USA. tuttl006@umn.edu. |
المصدر: | Journal of racial and ethnic health disparities [J Racial Ethn Health Disparities] 2024 Aug; Vol. 11 (4), pp. 2407-2415. Date of Electronic Publication: 2023 Jul 11. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101628476 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2196-8837 (Electronic) Linking ISSN: 21968837 NLM ISO Abbreviation: J Racial Ethn Health Disparities Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: [Cham] : Springer International Publishing |
مواضيع طبية MeSH: | Colonic Neoplasms*/mortality , Colonic Neoplasms*/ethnology , Colonic Neoplasms*/therapy , Alaska Natives*/statistics & numerical data , Databases, Factual*, Humans ; Male ; Female ; Middle Aged ; Aged ; United States/epidemiology ; Indians, North American/statistics & numerical data ; Adult ; Health Status Disparities ; Aged, 80 and over ; Neoplasm Staging ; White People/statistics & numerical data ; Kaplan-Meier Estimate |
مستخلص: | Background: Studies demonstrate higher mortality rates from colon cancer in American Indian/Alaskan Native (AI/AN) patients compared to non-Hispanic White (nHW). We aim to identify factors that contribute to survival disparities. Methods: We used the National Cancer Database to identify AI/AN (n = 2127) and nHW (n = 527,045) patients with stage I-IV colon cancer from 2004 to 2016. Overall survival among stage I-IV colon cancer patients was estimated by Kaplan-Meier analysis; Cox proportional hazard ratios were used to identify independent predictors of survival. Results: AI/AN patients with stage I-III disease had significantly shorter median survival than nHW (73 vs 77 months, respectively; p < 0.001); there were no differences in survival for stage IV. Adjusted analyses demonstrated that AI/AN race was an independent predictor of higher overall mortality compared to nHW (HR 1.19, 95% CI 1.01-1.33, p = 0.002). Importantly, compared to nHW, AI/AN were younger, had more comorbidities, had greater rurality, had more left-sided colon cancers, had higher stage but lower grade tumors, were less frequently treated at an academic facility, were more likely to experience a delay in initiation of chemotherapy, and were less likely to receive adjuvant chemotherapy for stage III disease. We found no differences in sex, receipt of surgery, or adequacy of lymph node dissection. Conclusion: We found patient, tumor, and treatment factors that potentially contribute to worse survival rates observed in AI/AN colon cancer patients. Limitations include the heterogeneity of AI/AN patients and the use of overall survival as an endpoint. Additional studies are needed to implement strategies to eliminate disparities. (© 2023. W. Montague Cobb-NMA Health Institute.) |
References: | American Cancer Society. Cancer facts & figures 2020. American Cancer Society. Accessed February 12, 2021. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2020/cancer-facts-and-figures-2020.pdf. White MC, Espey DK, Swan J, et al. Disparities in cancer mortality and incidence among American Indians and Alaska natives in the United States. Am J Public Health. 2014;104:377–87. https://doi.org/10.2105/AJPH.2013.301673 . (PMID: 10.2105/AJPH.2013.301673) Espey DK, Wu XC, Swan J, et al. Annual report to the nation on the status of cancer, 1975–2004, featuring cancer in American Indians and Alaska Natives. Cancer. 2007;110:2119–52. (PMID: 10.1002/cncr.2304417939129) Siegel RL, Miller KD, Goding Sauer A, et al. Colorectal cancer statistics, 2020. CA Cancer J Clin. 2020;70:145–64. https://doi.org/10.1002/cncr.23044 . (PMID: 10.1002/cncr.2304432133645) Haverkamp D, Redwood D, Roik E, Vindigni S, Thomas T. Elevated colorectal cancer incidence among American Indian/Alaska Native persons in Alaska compared to other populations worldwide. Int J Circumpolar Health. 2023;82(1):2184749. https://doi.org/10.1080/22423982.2023.2184749 . (PMID: 10.1080/22423982.2023.2184749368671069987760) Zavala VA, Bracci PM, Carethers JM, et al. Cancer health disparities in racial/ethnic minorities in the United States. Br J Cancer. 2021;124(2):315–32. https://doi.org/10.1038/s41416-020-01038-6 . (PMID: 10.1038/s41416-020-01038-632901135) Jackson CS, Oman M, Patel AM, Vega KJ. Health disparities in colorectal cancer among racial and ethnic minorities in the United States. J Gastrointest Oncol. 2016;7:S32–43. https://doi.org/10.3978/j.issn.2078-6891.2015.039 . (PMID: 10.3978/j.issn.2078-6891.2015.039270348114783613) Cueto CV, Szeja S, Wertheim BC, et al. Disparities in treatment and survival of white and native American patients with colorectal cancer: a SEER analysis. J Am Coll Surg. 2011;213:469–74. https://doi.org/10.1016/j.jamcollsurg.2011.05.026 . (PMID: 10.1016/j.jamcollsurg.2011.05.02621723155) Javid SH, Varghese TK, Morris AM, et al. Guideline-concordant cancer care and survival among American Indian/Alaskan Native patients. Cancer. 2014;120:2183–90. https://doi.org/10.1002/cncr.28683 . (PMID: 10.1002/cncr.2868324711210) Simianu VV, Morris AM, Varghese TK Jr, et al. Evaluating disparities in inpatient surgical cancer care among American Indian/Alaska Native patients. Am J Surg. 2016;212:297–304. https://doi.org/10.1016/j.amjsurg.2015.10.030 . (PMID: 10.1016/j.amjsurg.2015.10.030268461764939142) Longacre CF, Marmor S, Altman AM, et al. Patterns of treatment and survival among American Indian and Alaska Native Women with Breast Cancer, 2000–2015. J Health Care Poor Underserved. 2020;31:1308–22. https://doi.org/10.1353/hpu.2020.0096 . (PMID: 10.1353/hpu.2020.009633416696) Watson M, Benard V, Thomas C, et al. Cervical cancer incidence and mortality among American Indian and Alaska Native women, 1999–2009. Am J Public Health. 2014;104:S415–22. https://doi.org/10.2105/AJPH.2013.301681 . (PMID: 10.2105/AJPH.2013.301681247546504035877) Plescia M, Henley SJ, Pate A, et al. Lung cancer deaths among American Indians and Alaska Natives, 1990–2009. Am J Public Health. 2014;104:S388–95. https://doi.org/10.2105/AJPH.2013.301609 . (PMID: 10.2105/AJPH.2013.301609247546134035876) Li J, Weir HK, Jim MA, et al. Kidney cancer incidence and mortality among American Indians and Alaska Natives in the United States, 1990–2009. Am J Public Health. 2014;104:S396–403. https://doi.org/10.2105/AJPH.2013.301616 . (PMID: 10.2105/AJPH.2013.301616247546554035892) Islami F, Miller KD, Siegel RL, et al. Disparities in liver cancer occurrence in the United States by race/ethnicity and state. CA Cancer J Clin. 2017;67:273–89. https://doi.org/10.3322/caac.21402 . (PMID: 10.3322/caac.2140228586094) Henley SJ, Weir HK, Jim MA, et al. Gallbladder cancer incidence and mortality, United States 1999–2011. Cancer Epidemiol Biomarkers Prev. 2015;24:1319–26. https://doi.org/10.1158/1055-9965.EPI-15-0199 . (PMID: 10.1158/1055-9965.EPI-15-019926070529) Thuraisingam R, Jandova J, Pandit V, et al. Assessing the national trends in colon cancer among Native Americans: a 12 year SEER database study. Am J Surg. 2017;214:228–31. https://doi.org/10.1016/j.amjsurg.2016.11.033 . (PMID: 10.1016/j.amjsurg.2016.11.03328010880) Perdue DG, Haverkamp D, Perkins C, et al. Geographic variation in colorectal cancer incidence and mortality, age of onset, and stage at diagnosis among American Indian and Alaska Native people, 1990–2009. Am J Public Health. 2014;104:S404–14. https://doi.org/10.2105/AJPH.2013.301654 . (PMID: 10.2105/AJPH.2013.301654247546574035875) Wolf AMD, Fontham ETH, Church TR, et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA Cancer J Clin. 2018;68:250–81. https://doi.org/10.3322/caac.21457 . (PMID: 10.3322/caac.2145729846947) Rahman R, Schmaltz C, Jackson CS, et al. Increased risk for colorectal cancer under age 50 in racial and ethnic minorities living in the United States. Cancer Med. 2015;4:1863–70. https://doi.org/10.1002/cam4.560 . (PMID: 10.1002/cam4.560264719635123715) Boardman LA, Lanier AP, French AJ, et al. Frequency of defective DNA mismatch repair in colorectal cancer among the Alaska Native people. Cancer Epidemiol Biomarkers Prev. 2007;16:2344–50. https://doi.org/10.1158/1055-9965.EPI-07-0577 . (PMID: 10.1158/1055-9965.EPI-07-057718006922) Holm JE, Vogeltanz-Holm N, Poltavski D, McDonald L. Assessing health status, behavioral risks, and health disparities in American Indians living on the northern plains of the U.S. Public Health Rep. 2010;125:68–78. https://doi.org/10.1177/003335491012500110 . (PMID: 10.1177/003335491012500110204021982789818) Steele CB, Cardinez CJ, Richardson LC, et al. Surveillance for health behaviors of American Indians and Alaska natives - findings from the behavioral risk factor surveillance system, 2000–2006. Cancer. 2008;113:1131–41. https://doi.org/10.1002/cncr.23727 . (PMID: 10.1002/cncr.2372718720374) Schumacher MC, Slattery ML, Lanier AP, et al. Prevalence and predictors of cancer screening among American Indian and Alaska Native people: the EARTH study. Cancer Causes Control. 2008;19:725–37. https://doi.org/10.1007/s10552-008-9135-8 . (PMID: 10.1007/s10552-008-9135-8183070482574651) Day LW, Espey DK, Madden E, et al. Screening prevalence and incidence of colorectal cancer among American Indian/Alaskan natives in the Indian Health Service. Dig Dis Sci. 2011;56:2104–13. https://doi.org/10.1007/s10620-010-1528-3 . (PMID: 10.1007/s10620-010-1528-3212346883112488) Filippi MK, Braiuca S, Cully L, et al. American Indian perceptions of colorectal cancer screening: viewpoints from adults under age 50. J Cancer Educ. 2013;28:100–8. https://doi.org/10.1007/s13187-012-0428-y . (PMID: 10.1007/s13187-012-0428-y230865363580281) Sunny A, Rustveld L. The role of patient navigation on colorectal cancer screening completion and education: a review of the literature. J Cancer Educ. 2018;33:251–9. https://doi.org/10.1007/s13187-016-1140-0 . (PMID: 10.1007/s13187-016-1140-027878766) Sanford NN, Dharwadkar P, Murphy CC. Early-onset colorectal cancer: more than one side to the story. Color Cancer. 2020;9:CRC28. (PMID: 10.2217/crc-2020-0016) Gao P, Huang XZ, Song YX, et al. Impact of timing of adjuvant chemotherapy on survival in stage III colon cancer: a population-based study. BMC Cancer. 2018;18:1–15. (PMID: 10.1186/s12885-018-4138-7) Cabo J, Shu X, Shu XO, et al. Treatment at academic centers decreases insurance-based survival disparities in colon cancer. J Surg Res. 2020;245:265–72. https://doi.org/10.1016/j.jss.2019.07.059 . (PMID: 10.1016/j.jss.2019.07.05931421372) Bilimoria KY, Bentrem DJ, Stewart AK, et al. Comparison of commission on cancer-approved and -nonapproved hospitals in the United States: implications for studies that use the National Cancer Data Base. J Clin Oncol. 2009;27:4177–81. https://doi.org/10.1200/JCO.2008.21.7018 . (PMID: 10.1200/JCO.2008.21.701819636004) Winchester DP, Stewart AK, Bura C, Jones RS. The national cancer data base: a clinical surveillance and quality improvement tool. J Surg Oncol. 2004;85:1–3. https://doi.org/10.1002/jso.10320 . (PMID: 10.1002/jso.1032014696080) Vogel JD, Eskicioglu C, Weiser MR, et al. The American society of colon and rectal surgeons clinical practice guidelines for the treatment of colon cancer. Dis Colon Rectum. 2017;60:999–1017. https://doi.org/10.1097/DCR.0000000000000926 . (PMID: 10.1097/DCR.000000000000092628891842) |
فهرسة مساهمة: | Keywords: American Indian/Alaskan Native; Colorectal cancer; Health equity; Racial disparities |
تواريخ الأحداث: | Date Created: 20230711 Date Completed: 20240710 Latest Revision: 20240710 |
رمز التحديث: | 20240711 |
DOI: | 10.1007/s40615-023-01706-2 |
PMID: | 37432562 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2196-8837 |
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DOI: | 10.1007/s40615-023-01706-2 |