دورية أكاديمية

Mpox: Rapid Evidence Review.

التفاصيل البيبلوغرافية
العنوان: Mpox: Rapid Evidence Review.
المؤلفون: Saguil A; University of Florida College of Medicine, Gainesville, Florida., Krebs L; University of Florida College of Medicine, Gainesville, Florida., Choe U; Florida Department of Health in Pinellas County, St. Petersburg, Florida.
المصدر: American family physician [Am Fam Physician] 2023 Jul; Vol. 108 (1), pp. 78-83.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: American Academy of General Practice Country of Publication: United States NLM ID: 1272646 Publication Model: Print Cited Medium: Internet ISSN: 1532-0650 (Electronic) Linking ISSN: 0002838X NLM ISO Abbreviation: Am Fam Physician Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Kansas City, Mo., American Academy of General Practice.
مواضيع طبية MeSH: Exanthema* , Mpox (monkeypox)* , Sexual and Gender Minorities* , Smallpox*, Humans ; Male ; Homosexuality, Male
مستخلص: Mpox (formerly monkeypox) is a DNA virus of the Orthopoxvirus genus, similar to smallpox. Although mpox was endemic to the Democratic Republic of the Congo and parts of Africa, increasing numbers of cases were reported worldwide in 2022. More than 30,000 cases have been reported in the United States, and worldwide 98% of cases are found in men who have sex with men. Transmission is primarily through contact with skin lesions. The rash of mpox is often vesiculopustular and may be localized to the anogenital region or distributed on the face, trunk, limbs, palms, and soles. Two vaccines are available for pre- or postexposure prophylaxis. Jynneos (smallpox and mpox vaccine, live, nonreplicating) is a live, attenuated vaccine that is safe for patients who are immunocompromised. ACAM2000 (smallpox [vaccinia] vaccine, live) is a live vaccinia virus vaccine that should be given only to immunocompetent, nonpregnant people and should be avoided in those with skin conditions such as atopic dermatitis. For most people infected with mpox, the disease is mild and self-limiting. Antiviral treatments such as tecovirimat, cidofovir, or brincidofovir may be considered for use in individuals who have or are at high risk of severe disease. Possible complications of mpox include anogenital pain, bacterial superinfections of skin lesions, dehydration secondary to oral lesions, encephalitis, keratitis, and respiratory distress. To date, 38 deaths have been reported in the United States.
تواريخ الأحداث: Date Created: 20230713 Date Completed: 20230807 Latest Revision: 20231213
رمز التحديث: 20231215
PMID: 37440743
قاعدة البيانات: MEDLINE