دورية أكاديمية
Chlamydia trachomatis seropositivity among women with tubal factor infertility and fertile controls: a comparative study.
| العنوان: | Chlamydia trachomatis seropositivity among women with tubal factor infertility and fertile controls: a comparative study. |
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| المؤلفون: | Odelola OI; Department of Obstetrics and Gynaecology, Olabisi Onabanjo University Teaching Hospital Sagamu, Ogun State, Nigeria., Akadri AA; Department of Obstetrics and Gynaecology, Babcock University, Ilishan-Remo, Ogun State, Nigeria. |
| المصدر: | The Pan African medical journal [Pan Afr Med J] 2023 Apr 14; Vol. 44, pp. 178. Date of Electronic Publication: 2023 Apr 14 (Print Publication: 2023). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: African Field Epidemiology Network Country of Publication: Uganda NLM ID: 101517926 Publication Model: eCollection Cited Medium: Internet ISSN: 1937-8688 (Electronic) NLM ISO Abbreviation: Pan Afr Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kampala, Uganda : African Field Epidemiology Network |
| مواضيع طبية MeSH: | Infertility, Female*/etiology , Chlamydia Infections*/complications , Chlamydia Infections*/epidemiology , Chlamydia Infections*/diagnosis, Pregnancy ; Humans ; Female ; Male ; Chlamydia trachomatis ; Cross-Sectional Studies ; Fertility ; Antibodies, Bacterial |
| مستخلص: | Introduction: Chlamydia trachomatis is the most reported bacterial sexually transmitted infection and if not properly treated may lead to tubal blockage. Tubal factor infertility is the most common form of infertility in Nigeria. This study was designed to determine the usefulness of chlamydia antibody testing in diagnosis of tubal factor infertility. Methods: this was a comparative cross-sectional study conducted in Olabisi Onabanjo University Teaching Hospital Sagamu. One hundred and forty-seven women with tubal blockage on hysterosalpingography and confirmed with laparoscopy, and pregnant control were recruited using convenience sampling method. Information obtained and chlamydia assay results were entered into a computer and analyzed using SPSS version 21. Chi-square was used to determine association between categorical variables. Logistic regression analysis was used to determine the risk factors associated with chlamydia infection. Results: ninety-four (63.9%) of the women with tubal factor infertility were positive for chlamydia IgG antibodies while 37(25.2%) women in the control group had positive results for IgG antibody. This was statistically significant (P=0.001). Analysis using multivariate logistic regression shows early age of coitarche, presence of multiple sexual partners and previous sexually transmitted infection were significantly associated with chlamydia infection (P=0.001). Conclusion: there was a strong association between chlamydia seropositivity and tubal blockage. Early age at coitarche, previous sexually transmitted infection and multiple sexual partners are significant risk factors for chlamydial infection. Chlamydia trachomatis antibody testing could be used as marker for tubal blockage when evaluating infertile patient. Competing Interests: The authors declare no competing interests. (Copyright: Oluwaseyi Isaiah Odelola et al.) |
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| فهرسة مساهمة: | Keywords: Chlamydia trachomatis; antibody titre; hysterosalpingography; laparoscopy; tubal factor infertility |
| المشرفين على المادة: | 0 (Antibodies, Bacterial) |
| تواريخ الأحداث: | Date Created: 20230717 Date Completed: 20230718 Latest Revision: 20230718 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC10349630 |
| DOI: | 10.11604/pamj.2023.44.178.29443 |
| PMID: | 37455888 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1937-8688 |
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| DOI: | 10.11604/pamj.2023.44.178.29443 |