دورية أكاديمية
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Non-targeted Screening of Natural Products from 288 Fungal Endophytes from Canadian Fruit Crops.

التفاصيل البيبلوغرافية
العنوان: Non-targeted Screening of Natural Products from 288 Fungal Endophytes from Canadian Fruit Crops.
المؤلفون: DesRochers N; London Research and Development Centre, Agriculture and Agri-Food Canada, 1391 Sandford Street, London, Ontario N5V 4T3, Canada.; Department of Chemistry, University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7, Canada., Renaud JB; London Research and Development Centre, Agriculture and Agri-Food Canada, 1391 Sandford Street, London, Ontario N5V 4T3, Canada., Tanney JB; Pacific Forestry Centre, Canadian Forest Service, Natural Resources Canada, Victoria, British Columbia V8Z 1M5, Canada., Ibrahim A; McMaster University, 1290 Main St. W, Hamilton, Ontario L8S 4L8, Canada., Yeung KK; Department of Chemistry, University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7, Canada.; Department of Biochemistry, University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7, Canada., Sumarah MW; London Research and Development Centre, Agriculture and Agri-Food Canada, 1391 Sandford Street, London, Ontario N5V 4T3, Canada.; Department of Chemistry, University of Western Ontario, 1151 Richmond Street, London, Ontario N6A 3K7, Canada.
المصدر: ACS omega [ACS Omega] 2023 Jun 27; Vol. 8 (27), pp. 24561-24572. Date of Electronic Publication: 2023 Jun 27 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Washington, D.C. : American Chemical Society, [2016]-
مستخلص: Many diverse species of fungi naturally occur as endophytes in plants. The majority of these fungi produce secondary metabolites of diverse structures and biological activities. Culture extracts from 288 fungi isolated from surface-sterilized blueberries, cranberries, raspberries, and grapes were analyzed by LC-HRMS/MS. Global Natural Products Social (GNPS) Molecular Networking modeling was used to investigate the secondary metabolites in the extracts. This technique increased the speed and simplicity of dereplicating the extracts, targeting new compounds that are structurally related. In total, 60 known compounds were dereplicated from this collection and seven new compounds were identified. These previously unknown compounds are targets for purification, characterization, and bioactivity testing in future studies. The fungal endophytes characterized in this study are potential candidates for providing bio-protection to the host plant with a reduced reliance on chemical pesticides.
Competing Interests: The authors declare no competing financial interest.
(© 2023 The Authors. Published by American Chemical Society.)
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تواريخ الأحداث: Date Created: 20230717 Latest Revision: 20230718
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10339433
DOI: 10.1021/acsomega.3c02786
PMID: 37457466
قاعدة البيانات: MEDLINE
الوصف
تدمد:2470-1343
DOI:10.1021/acsomega.3c02786